223 research outputs found
Lumen-intima and media-adventitia segmentation in IVUS images using supervised classifications of arterial layers and morphological structures
Background: Intravascular ultrasound (IVUS) provides axial grey-scale images of blood vessels. The large number of images require automatic analysis, specifically to identify the lumen and outer vessel wall. However, the high amount of noise, the presence of artifacts and anatomical structures, such as bifurcations, calcifications and fibrotic plaques, usually hinder the proper automatic segmentation of the vessel wall. Methods: Lumen, media, adventitia and surrounding tissues are automatically detected using Support Vector Machines (SVMs). The classification performance of the SVMs vary according to the kind of structure present within each region of the image. Random Forest (RF) is used to detect different morphological structures and to modify the initial layer classification depending on the detected structure. The resulting classification maps are fed into a segmentation method based on deformable contours to detect lumen-intima (LI) and media-adventitia (MA) interfaces. Results: The modifications in the layer classifications according to the presence of structures proved to be effective improving LI and MA segmentations. The proposed method reaches a Jaccard Measure (JM) of 0.88 ± 0.08 for LI segmentation, compared with 0.88 ± 0.05 of a semiautomatic method. When looking at MA, our method reaches a JM of 0.84 ± 0.09, and outperforms previous automatic methods in terms of HD, with 0.51mm ± 0.30. Conclusions: A simple modification to the arterial layer classification produces results that match and improve state-of-the-art fully-automatic segmentation methods for LI and MA in 20MHz IVUS images. For LI segmentation, the proposed automatic method performs accurately as semi-automatic methods. For MA segmentation, our method matched the quality of state-of-the-art automatic methods described in the literature. Furthermore, our implementation is modular and open-source, allowing for future extensions and improvements.Fil: Lo Vercio, Lucas. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Exactas. Grupo de Plasmas Densos Magnetizados. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Grupo de Plasmas Densos Magnetizados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; ArgentinaFil: del Fresno, Mirta Mariana. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Exactas. Grupo de Plasmas Densos Magnetizados. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Grupo de Plasmas Densos Magnetizados; ArgentinaFil: Larrabide, Ignacio. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Exactas. Grupo de Plasmas Densos Magnetizados. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Grupo de Plasmas Densos Magnetizados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentin
Advanced deep learning methodology for accurate, real-time segmentation of high-resolution intravascular ultrasound images
AIMS: The aim of this study is to develop and validate a deep learning (DL) methodology capable of automated and accurate segmentation of intravascular ultrasound (IVUS) image sequences in real-time. METHODS AND RESULTS: IVUS segmentation was performed by two experts who manually annotated the external elastic membrane (EEM) and lumen borders in the end-diastolic frames of 197 IVUS sequences portraying the native coronary arteries of 65 patients. The IVUS sequences of 177 randomly-selected vessels were used to train and optimise a novel DL model for the segmentation of IVUS images. Validation of the developed methodology was performed in 20 vessels using the estimations of two expert analysts as the reference standard. The mean difference for the EEM, lumen and plaque area between the DL-methodology and the analysts was ≤0.23mm2 (standard deviation ≤0.85mm2), while the Hausdorff and mean distance differences for the EEM and lumen borders was ≤0.19 mm (standard deviation≤0.17 mm). The agreement between DL and experts was similar to experts' agreement (Williams Index ranges: 0.754-1.061) with similar results in frames portraying calcific plaques or side branches. CONCLUSIONS: The developed DL-methodology appears accurate and capable of segmenting high-resolution real-world IVUS datasets. These features are expected to facilitate its broad adoption and enhance the applications of IVUS in clinical practice and research
Thin Cap Fibroatheroma Detection in Virtual Histology Images Using Geometric and Texture Features
Atherosclerotic plaque rupture is the most common mechanism responsible for a majority
of sudden coronary deaths. The precursor lesion of plaque rupture is thought to be a thin
cap fibroatheroma (TCFA), or “vulnerable plaque”. Virtual Histology-Intravascular Ultrasound
(VH-IVUS) images are clinically available for visualising colour-coded coronary artery tissue.
However, it has limitations in terms of providing clinically relevant information for identifying
vulnerable plaque. The aim of this research is to improve the identification of TCFA using VH-IVUS
images. To more accurately segment VH-IVUS images, a semi-supervised model is developed by
means of hybrid K-means with Particle Swarm Optimisation (PSO) and a minimum Euclidean
distance algorithm (KMPSO-mED). Another novelty of the proposed method is fusion of different
geometric and informative texture features to capture the varying heterogeneity of plaque components
and compute a discriminative index for TCFA plaque, while the existing research on TCFA detection
has only focused on the geometric features. Three commonly used statistical texture features are
extracted from VH-IVUS images: Local Binary Patterns (LBP), Grey Level Co-occurrence Matrix
(GLCM), and Modified Run Length (MRL). Geometric and texture features are concatenated in
order to generate complex descriptors. Finally, Back Propagation Neural Network (BPNN), kNN
(K-Nearest Neighbour), and Support Vector Machine (SVM) classifiers are applied to select the best
classifier for classifying plaque into TCFA and Non-TCFA. The present study proposes a fast and
accurate computer-aided method for plaque type classification. The proposed method is applied to 588 VH-IVUS images obtained from 10 patients. The results prove the superiority of the proposed
method, with accuracy rates of 98.61% for TCFA plaque.This research was funded by Universiti Teknologi Malaysia (UTM) under Research University
Grant Vot-02G31, and the Ministry of Higher Education Malaysia (MOHE) under the Fundamental Research Grant
Scheme (FRGS Vot-4F551) for the completion of the research. The work and the contribution were also supported
by the project Smart Solutions in Ubiquitous Computing Environments, Grant Agency of Excellence, University
of Hradec Kralove, Faculty of Informatics and Management, Czech Republic (under ID: UHK-FIM-GE-2018).
Furthermore, the research is also partially supported by the Spanish Ministry of Science, Innovation and
Universities with FEDER funds in the project TIN2016-75850-R
Recent Advances in Machine Learning Applied to Ultrasound Imaging
Machine learning (ML) methods are pervading an increasing number of fields of application because of their capacity to effectively solve a wide variety of challenging problems. The employment of ML techniques in ultrasound imaging applications started several years ago but the scientific interest in this issue has increased exponentially in the last few years. The present work reviews the most recent (2019 onwards) implementations of machine learning techniques for two of the most popular ultrasound imaging fields, medical diagnostics and non-destructive evaluation. The former, which covers the major part of the review, was analyzed by classifying studies according to the human organ investigated and the methodology (e.g., detection, segmentation, and/or classification) adopted, while for the latter, some solutions to the detection/classification of material defects or particular patterns are reported. Finally, the main merits of machine learning that emerged from the study analysis are summarized and discussed. © 2022 by the authors. Licensee MDPI, Basel, Switzerland
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