3,059 research outputs found
Towards Exascale Scientific Metadata Management
Advances in technology and computing hardware are enabling scientists from
all areas of science to produce massive amounts of data using large-scale
simulations or observational facilities. In this era of data deluge, effective
coordination between the data production and the analysis phases hinges on the
availability of metadata that describe the scientific datasets. Existing
workflow engines have been capturing a limited form of metadata to provide
provenance information about the identity and lineage of the data. However,
much of the data produced by simulations, experiments, and analyses still need
to be annotated manually in an ad hoc manner by domain scientists. Systematic
and transparent acquisition of rich metadata becomes a crucial prerequisite to
sustain and accelerate the pace of scientific innovation. Yet, ubiquitous and
domain-agnostic metadata management infrastructure that can meet the demands of
extreme-scale science is notable by its absence.
To address this gap in scientific data management research and practice, we
present our vision for an integrated approach that (1) automatically captures
and manipulates information-rich metadata while the data is being produced or
analyzed and (2) stores metadata within each dataset to permeate
metadata-oblivious processes and to query metadata through established and
standardized data access interfaces. We motivate the need for the proposed
integrated approach using applications from plasma physics, climate modeling
and neuroscience, and then discuss research challenges and possible solutions
RegenBase: a knowledge base of spinal cord injury biology for translational research.
Spinal cord injury (SCI) research is a data-rich field that aims to identify the biological mechanisms resulting in loss of function and mobility after SCI, as well as develop therapies that promote recovery after injury. SCI experimental methods, data and domain knowledge are locked in the largely unstructured text of scientific publications, making large scale integration with existing bioinformatics resources and subsequent analysis infeasible. The lack of standard reporting for experiment variables and results also makes experiment replicability a significant challenge. To address these challenges, we have developed RegenBase, a knowledge base of SCI biology. RegenBase integrates curated literature-sourced facts and experimental details, raw assay data profiling the effect of compounds on enzyme activity and cell growth, and structured SCI domain knowledge in the form of the first ontology for SCI, using Semantic Web representation languages and frameworks. RegenBase uses consistent identifier schemes and data representations that enable automated linking among RegenBase statements and also to other biological databases and electronic resources. By querying RegenBase, we have identified novel biological hypotheses linking the effects of perturbagens to observed behavioral outcomes after SCI. RegenBase is publicly available for browsing, querying and download.Database URL:http://regenbase.org
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FAIR principles and the IEDB: short-term improvements and a long-term vision of OBO-foundry mediated machine-actionable interoperability.
The Immune Epitope Database (IEDB), at www.iedb.org, has the mission to make published experimental data relating to the recognition of immune epitopes easily available to the scientific public. By presenting curated data in a searchable database, we have liberated it from the tables and figures of journal articles, making it more accessible and usable by immunologists. Recently, the principles of Findability, Accessibility, Interoperability and Reusability have been formulated as goals that data repositories should meet to enhance the usefulness of their data holdings. We here examine how the IEDB complies with these principles and identify broad areas of success, but also areas for improvement. We describe short-term improvements to the IEDB that are being implemented now, as well as a long-term vision of true 'machine-actionable interoperability', which we believe will require community agreement on standardization of knowledge representation that can be built on top of the shared use of ontologies
The Revised TESS Input Catalog and Candidate Target List
We describe the catalogs assembled and the algorithms used to populate the
revised TESS Input Catalog (TIC), based on the incorporation of the Gaia second
data release. We also describe a revised ranking system for prioritizing stars
for 2-minute cadence observations, and assemble a revised Candidate Target List
(CTL) using that ranking. The TIC is available on the Mikulski Archive for
Space Telescopes (MAST) server, and an enhanced CTL is available through the
Filtergraph data visualization portal system at the URL
http://filtergraph.vanderbilt.edu/tess_ctl.Comment: 30 pages, 16 figures, submitted to AAS Journals; provided to the
community in advance of publication in conjunction with public release of the
TIC/CTL on 28 May 201
Theory and Practice of Data Citation
Citations are the cornerstone of knowledge propagation and the primary means
of assessing the quality of research, as well as directing investments in
science. Science is increasingly becoming "data-intensive", where large volumes
of data are collected and analyzed to discover complex patterns through
simulations and experiments, and most scientific reference works have been
replaced by online curated datasets. Yet, given a dataset, there is no
quantitative, consistent and established way of knowing how it has been used
over time, who contributed to its curation, what results have been yielded or
what value it has.
The development of a theory and practice of data citation is fundamental for
considering data as first-class research objects with the same relevance and
centrality of traditional scientific products. Many works in recent years have
discussed data citation from different viewpoints: illustrating why data
citation is needed, defining the principles and outlining recommendations for
data citation systems, and providing computational methods for addressing
specific issues of data citation.
The current panorama is many-faceted and an overall view that brings together
diverse aspects of this topic is still missing. Therefore, this paper aims to
describe the lay of the land for data citation, both from the theoretical (the
why and what) and the practical (the how) angle.Comment: 24 pages, 2 tables, pre-print accepted in Journal of the Association
for Information Science and Technology (JASIST), 201
Enhanced Search for Educational Resources - A Perspective and a Prototype from ccLearn
Users of search tools who seek educational materials on the Internet are typically presented with either a web-scale search (e.g., Google or Yahoo) or a specialized, site-specific tool. The specialized search tools often rely upon custom data fields, such as user-entered ratings, to provide additional value. As currently designed, these systems are generally too labor intensive to manage and scale up beyond a single site or set of resources.However, custom (or structured) data of some form is necessary if search outcomes foreducational materials are to be improved. For example, design criteria and evaluative metrics are crucial attributes for educational resources, and these currently require human labeling and verification. Thus, one challenge is to design a search tool that capitalizes on available structured data (also called metadata) but is not crippled if the data are missing. This information should be amenable to repurposing by anyone, which means that it must be archived in a manner that can be discovered and leveraged easily.In this paper, we describe the extent to which DiscoverEd, a prototype developed by ccLearn, meets the design challenge of a scalable, enhanced search platform for educational resources. We then explore some of the key challenges regarding enhanced search for topic-specific Internet resources generally. We conclude by illustrating some possible future developments and third-party enhancements to the DiscoverEd prototype
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