Personalized data analytics for internet-of-things-based health monitoring

The Internet-of-Things (IoT) has great potential to fundamentally alter the delivery of modern healthcare, enabling healthcare solutions outside the limits of conventional clinical settings. It can offer ubiquitous monitoring to at-risk population groups and allow diagnostic care, preventive care, and early intervention in everyday life. These services can have profound impacts on many aspects of health and well-being. However, this field is still at an infancy stage, and the use of IoT-based systems in real-world healthcare applications introduces new challenges. Healthcare applications necessitate satisfactory quality attributes such as reliability and accuracy due to their mission-critical nature, while at the same time, IoT-based systems mostly operate over constrained shared sensing, communication, and computing resources. There is a need to investigate this synergy between the IoT technologies and healthcare applications from a user-centered perspective. Such a study should examine the role and requirements of IoT-based systems in real-world health monitoring applications. Moreover, conventional computing architecture and data analytic approaches introduced for IoT systems are insufficient when used to target health and well-being purposes, as they are unable to overcome the limitations of IoT systems while fulfilling the needs of healthcare applications. This thesis aims to address these issues by proposing an intelligent use of data and computing resources in IoT-based systems, which can lead to a high-level performance and satisfy the stringent requirements. For this purpose, this thesis first delves into the state-of-the-art IoT-enabled healthcare systems proposed for in-home and in-hospital monitoring. The findings are analyzed and categorized into different domains from a user-centered perspective. The selection of home-based applications is focused on the monitoring of the elderly who require more remote care and support compared to other groups of people. In contrast, the hospital-based applications include the role of existing IoT in patient monitoring and hospital management systems. Then, the objectives and requirements of each domain are investigated and discussed. This thesis proposes personalized data analytic approaches to fulfill the requirements and meet the objectives of IoT-based healthcare systems. In this regard, a new computing architecture is introduced, using computing resources in different layers of IoT to provide a high level of availability and accuracy for healthcare services. This architecture allows the hierarchical partitioning of machine learning algorithms in these systems and enables an adaptive system behavior with respect to the user's condition. In addition, personalized data fusion and modeling techniques are presented, exploiting multivariate and longitudinal data in IoT systems to improve the quality attributes of healthcare applications. First, a real-time missing data resilient decision-making technique is proposed for health monitoring systems. The technique tailors various data resources in IoT systems to accurately estimate health decisions despite missing data in the monitoring. Second, a personalized model is presented, enabling variations and event detection in long-term monitoring systems. The model evaluates the sleep quality of users according to their own historical data. Finally, the performance of the computing architecture and the techniques are evaluated in this thesis using two case studies. The first case study consists of real-time arrhythmia detection in electrocardiography signals collected from patients suffering from cardiovascular diseases. The second case study is continuous maternal health monitoring during pregnancy and postpartum. It includes a real human subject trial carried out with twenty pregnant women for seven months

Two Sides of the Same Pillow: Unfolding the Relationship between Objective and Subjective Sleep Quality with Unsupervised Learning

Advances in digital health allow us to take an active part in monitoring and improving our sleep quality. Both, objectively recorded and subjectively perceived sleep quality impacts our general health and well-being. This research shows how these two dimensions of sleep quality can be captured with smartwatches and digital symptom trackers. We contribute to the gap in the literature on how recorded values from wearables and user-generated content from mobile applications can elevate each other. Analysing the recorded and re- ported sleep quality in a longitudinal sleep study (n=45) shows differences in how partic- ipants perceive their sleep. We address this need for personalization, by creating clusters of participants with a similar perception of sleep using unsupervised machine learning. Analysing these clusters provides us with a more wholesome understanding of their sleep quality and raises awareness for the uniqueness of individuals in digital health

Distributed Computing and Monitoring Technologies for Older Patients

This book summarizes various approaches for the automatic detection of health threats to older patients at home living alone. The text begins by briefly describing those who would most benefit from healthcare supervision. The book then summarizes possible scenarios for monitoring an older patient at home, deriving the common functional requirements for monitoring technology. Next, the work identifies the state of the art of technological monitoring approaches that are practically applicable to geriatric patients. A survey is presented on a range of such interdisciplinary fields as smart homes, telemonitoring, ambient intelligence, ambient assisted living, gerontechnology, and aging-in-place technology. The book discusses relevant experimental studies, highlighting the application of sensor fusion, signal processing and machine learning techniques. Finally, the text discusses future challenges, offering a number of suggestions for further research directions

EDMON - Electronic Disease Surveillance and Monitoring Network: A Personalized Health Model-based Digital Infectious Disease Detection Mechanism using Self-Recorded Data from People with Type 1 Diabetes

Through time, we as a society have been tested with infectious disease outbreaks of different magnitude, which often pose major public health challenges. To mitigate the challenges, research endeavors have been focused on early detection mechanisms through identifying potential data sources, mode of data collection and transmission, case and outbreak detection methods. Driven by the ubiquitous nature of smartphones and wearables, the current endeavor is targeted towards individualizing the surveillance effort through a personalized health model, where the case detection is realized by exploiting self-collected physiological data from wearables and smartphones. This dissertation aims to demonstrate the concept of a personalized health model as a case detector for outbreak detection by utilizing self-recorded data from people with type 1 diabetes. The results have shown that infection onset triggers substantial deviations, i.e. prolonged hyperglycemia regardless of higher insulin injections and fewer carbohydrate consumptions. Per the findings, key parameters such as blood glucose level, insulin, carbohydrate, and insulin-to-carbohydrate ratio are found to carry high discriminative power. A personalized health model devised based on a one-class classifier and unsupervised method using selected parameters achieved promising detection performance. Experimental results show the superior performance of the one-class classifier and, models such as one-class support vector machine, k-nearest neighbor and, k-means achieved better performance. Further, the result also revealed the effect of input parameters, data granularity, and sample sizes on model performances. The presented results have practical significance for understanding the effect of infection episodes amongst people with type 1 diabetes, and the potential of a personalized health model in outbreak detection settings. The added benefit of the personalized health model concept introduced in this dissertation lies in its usefulness beyond the surveillance purpose, i.e. to devise decision support tools and learning platforms for the patient to manage infection-induced crises

CrossCheck:toward passive sensing and detection of mental health changes in people with schizophrenia

Early detection of mental health changes in individuals with serious mental illness is critical for effective intervention. CrossCheck is the first step towards the passive monitoring of mental health indicators in patients with schizophrenia and paves the way towards relapse prediction and early intervention. In this paper, we present initial results from an ongoing randomized control trial, where passive smartphone sensor data is collected from 21 outpatients with schizophrenia recently discharged from hospital over a period ranging from 2-8.5 months. Our results indicate that there are statistically significant associations between automatically tracked behavioral features related to sleep, mobility, conversations, smartphone usage and self-reported indicators of mental health in schizophrenia. Using these features we build inference models capable of accurately predicting aggregated scores of mental health indicators in schizophrenia with a mean error of 7.6% of the score range. Finally, we discuss results on the level of personalization that is needed to account for the known variations within people. We show that by leveraging knowledge from a population with schizophrenia, it is possible to train accurate personalized models that require fewer individual-specific data to quickly adapt to new user

Detecting Steps Walking at very Low Speeds Combining Outlier Detection, Transition Matrices and Autoencoders from Acceleration Patterns

In this paper, we develop and validate a new algorithm to detect steps while walking at speeds between 30 and 40 steps per minute based on the data sensed from a single tri-axial accelerometer. The algorithm concatenates three consecutive phases. First, an outlier detection is performed on the sensed data based on the Mahalanobis distance to pre-detect candidate points in the acceleration time series that may contain a ground contact segment of data while walking. Second, the acceleration segment around the pre-detected point is used to calculate the transition matrix in order to capture the time dependencies. Finally, autoencoders, trained with data segments containing ground contact transition matrices from acceleration series from labeled steps are used to reconstruct the computed transition matrices at each pre-detected point. A similarity index is used to assess if the pre-selected point contains a true step in the 30-40 steps per minute speed range. Our experimental results, based on a database from three different participants performing similar activities to the target one, are able to achieve a recall = 0.88 with precision = 0.50 improving the results when directly applying the autoencoders to acceleration patterns (recall = 0.77 with precision = 0.50)

Discovering behavioural patterns using conversational technology for in-home health and well-being monitoring

Advancements in conversational AI have created unparalleled opportunities to promote the independence and well-being of older adults, including people living with dementia (PLWD). However, conversational agents have yet to demonstrate a direct impact in supporting target populations at home, particularly with long-term user benefits and clinical utility. We introduce an infrastructure fusing in-home activity data captured by Internet of Things (IoT) technologies with voice interactions using conversational technology (Amazon Alexa). We collect 3103 person-days of voice and environmental data across 14 households with PLWD to identify behavioural patterns. Interactions include an automated well-being questionnaire and 10 topics of interest, identified using topic modelling. Although a significant decrease in conversational technology usage was observed after the novelty phase across the cohort, steady state data acquisition for modelling was sustained. We analyse household activity sequences preceding or following Alexa interactions through pairwise similarity and clustering methods. Our analysis demonstrates the capability to identify individual behavioural patterns, changes in those patterns and the corresponding time periods. We further report that households with PLWD continued using Alexa following clinical events (e.g., hospitalisations), which offers a compelling opportunity for proactive health and well-being data gathering related to medical changes. Results demonstrate the promise of conversational AI in digital health monitoring for ageing and dementia support and offer a basis for tracking health and deterioration as indicated by household activity, which can inform healthcare professionals and relevant stakeholders for timely interventions. Future work will use the bespoke behavioural patterns extracted to create more personalised AI conversations

Machine Learning for Fatigue Detection using Fitbit Fitness Trackers

Fatigue can be a pre-cursor to many illnesses and injuries, and cause fatal work-related incidents. Fatigue detection has been traditionally performed in lab conditions with stationary medical-grade diagnostics equipment for electroencephalography making it impractical for many in-field scenarios. More recently, the ubiquitous use of wearable sensor-enabled technologies in sports, everyday life or fieldwork has enabled collecting large amounts of physiological information. According to recent studies, the collected biomarkers related to sleep, physical activity or heart rate have proven to be in correlation with fatigue, making it a natural fit for applying automated data analysis using Machine Learning. Accordingly, this paper presents our novel Machine Learning-driven approach to fatigue detection using biomarkers collected by general-purpose wearable fitness trackers. The developed method can successfully predict fatigue symptoms among target users, and the overall methodology can be further extended to other diagnostics scenarios which rely on collected wearable data.acceptedVersio

NILM techniques for intelligent home energy management and ambient assisted living: a review

The ongoing deployment of smart meters and different commercial devices has made electricity disaggregation feasible in buildings and households, based on a single measure of the current and, sometimes, of the voltage. Energy disaggregation is intended to separate the total power consumption into specific appliance loads, which can be achieved by applying Non-Intrusive Load Monitoring (NILM) techniques with a minimum invasion of privacy. NILM techniques are becoming more and more widespread in recent years, as a consequence of the interest companies and consumers have in efficient energy consumption and management. This work presents a detailed review of NILM methods, focusing particularly on recent proposals and their applications, particularly in the areas of Home Energy Management Systems (HEMS) and Ambient Assisted Living (AAL), where the ability to determine the on/off status of certain devices can provide key information for making further decisions. As well as complementing previous reviews on the NILM field and providing a discussion of the applications of NILM in HEMS and AAL, this paper provides guidelines for future research in these topics.Agência financiadora: Programa Operacional Portugal 2020 and Programa Operacional Regional do Algarve 01/SAICT/2018/39578 Fundação para a Ciência e Tecnologia through IDMEC, under LAETA: SFRH/BSAB/142998/2018 SFRH/BSAB/142997/2018 UID/EMS/50022/2019 Junta de Comunidades de Castilla-La-Mancha, Spain: SBPLY/17/180501/000392 Spanish Ministry of Economy, Industry and Competitiveness (SOC-PLC project): TEC2015-64835-C3-2-R MINECO/FEDERinfo:eu-repo/semantics/publishedVersio