14,558 research outputs found
Automated Classification of Periodic Variable Stars detected by the Wide-field Infrared Survey Explorer
We describe a methodology to classify periodic variable stars identified
using photometric time-series measurements constructed from the Wide-field
Infrared Survey Explorer (WISE) full-mission single-exposure Source Databases.
This will assist in the future construction of a WISE Variable Source Database
that assigns variables to specific science classes as constrained by the WISE
observing cadence with statistically meaningful classification probabilities.
We have analyzed the WISE light curves of 8273 variable stars identified in
previous optical variability surveys (MACHO, GCVS, and ASAS) and show that
Fourier decomposition techniques can be extended into the mid-IR to assist with
their classification. Combined with other periodic light-curve features, this
sample is then used to train a machine-learned classifier based on the random
forest (RF) method. Consistent with previous classification studies of variable
stars in general, the RF machine-learned classifier is superior to other
methods in terms of accuracy, robustness against outliers, and relative
immunity to features that carry little or redundant class information. For the
three most common classes identified by WISE: Algols, RR Lyrae, and W Ursae
Majoris type variables, we obtain classification efficiencies of 80.7%, 82.7%,
and 84.5% respectively using cross-validation analyses, with 95% confidence
intervals of approximately +/-2%. These accuracies are achieved at purity (or
reliability) levels of 88.5%, 96.2%, and 87.8% respectively, similar to that
achieved in previous automated classification studies of periodic variable
stars.Comment: 48 pages, 17 figures, 1 table, accepted by A
Julian Ernst Besag, 26 March 1945 -- 6 August 2010, a biographical memoir
Julian Besag was an outstanding statistical scientist, distinguished for his
pioneering work on the statistical theory and analysis of spatial processes,
especially conditional lattice systems. His work has been seminal in
statistical developments over the last several decades ranging from image
analysis to Markov chain Monte Carlo methods. He clarified the role of
auto-logistic and auto-normal models as instances of Markov random fields and
paved the way for their use in diverse applications. Later work included
investigations into the efficacy of nearest neighbour models to accommodate
spatial dependence in the analysis of data from agricultural field trials,
image restoration from noisy data, and texture generation using lattice models.Comment: 26 pages, 14 figures; minor revisions, omission of full bibliograph
One Problem, Many Solutions: Simple Statistical Approaches Help Unravel the Complexity of the Immune System in an Ecological Context
The immune system is a complex collection of interrelated and overlapping solutions to the problem of disease. To deal with this complexity, researchers have devised multiple ways to measure immune function and to analyze the resulting data. In this way both organisms and researchers employ many tactics to solve a complex problem. One challenge facing ecological immunologists is the question of how these many dimensions of immune function can be synthesized to facilitate meaningful interpretations and conclusions. We tackle this challenge by employing and comparing several statistical methods, which we used to test assumptions about how multiple aspects of immune function are related at different organizational levels. We analyzed three distinct datasets that characterized 1) species, 2) subspecies, and 3) among- and within-individual level differences in the relationships among multiple immune indices. Specifically, we used common principal components analysis (CPCA) and two simpler approaches, pair-wise correlations and correlation circles. We also provide a simple example of how these techniques could be used to analyze data from multiple studies. Our findings lead to several general conclusions. First, relationships among indices of immune function may be consistent among some organizational groups (e.g. months over the annual cycle) but not others (e.g. species); therefore any assumption of consistency requires testing before further analyses. Second, simple statistical techniques used in conjunction with more complex multivariate methods give a clearer and more robust picture of immune function than using complex statistics alone. Moreover, these simpler approaches have potential for analyzing comparable data from multiple studies, especially as the field of ecological immunology moves towards greater methodological standardization
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Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study.
Spices were used as food preservatives prior to the advent of refrigeration, suggesting the possibility of effects on microbiota. Previous studies have shown prebiotic activities in animals and in vitro, but there has not been a demonstration of prebiotic or postbiotic effects at culinary doses in humans. In this randomized placebo-controlled study, we determined in twenty-nine healthy adults the effects on the gut microbiota of the consumption daily of capsules containing 5 g of mixed spices at culinary doses by comparison to a matched control group consuming a maltodextrin placebo capsule. The 16S ribosomal RNA sequencing data were used for microbial characterization. Spice consumption resulted in a significant reduction in Firmicutes abundance (p < 0.033) and a trend of enrichment in Bacteroidetes (p < 0.097) compared to placebo group. Twenty-six operational taxonomic units (OTUs) were different between the spice and placebo groups after intervention. Furthermore, there was a significant negative correlation between fecal short-chain fatty acid propionate concentration and Firmicutes abundance in spice intervention group (p < 0.04). The production of individual fecal short-chain fatty acid was not significantly changed by spice consumption in this study. Mixed spices consumption significantly modified gut microbiota, suggesting a prebiotic effect of spice consumption at culinary doses
Stability
Reproducibility is imperative for any scientific discovery. More often than
not, modern scientific findings rely on statistical analysis of
high-dimensional data. At a minimum, reproducibility manifests itself in
stability of statistical results relative to "reasonable" perturbations to data
and to the model used. Jacknife, bootstrap, and cross-validation are based on
perturbations to data, while robust statistics methods deal with perturbations
to models. In this article, a case is made for the importance of stability in
statistics. Firstly, we motivate the necessity of stability for interpretable
and reliable encoding models from brain fMRI signals. Secondly, we find strong
evidence in the literature to demonstrate the central role of stability in
statistical inference, such as sensitivity analysis and effect detection.
Thirdly, a smoothing parameter selector based on estimation stability (ES),
ES-CV, is proposed for Lasso, in order to bring stability to bear on
cross-validation (CV). ES-CV is then utilized in the encoding models to reduce
the number of predictors by 60% with almost no loss (1.3%) of prediction
performance across over 2,000 voxels. Last, a novel "stability" argument is
seen to drive new results that shed light on the intriguing interactions
between sample to sample variability and heavier tail error distribution (e.g.,
double-exponential) in high-dimensional regression models with predictors
and independent samples. In particular, when
and the error distribution is
double-exponential, the Ordinary Least Squares (OLS) is a better estimator than
the Least Absolute Deviation (LAD) estimator.Comment: Published in at http://dx.doi.org/10.3150/13-BEJSP14 the Bernoulli
(http://isi.cbs.nl/bernoulli/) by the International Statistical
Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm
The Challenges of Globalization: The Strategic Role of Local Managers in Japanese-Owned U.S. Subsidiaries
[Excerpt] After spending billions of dollars moving manufacturing plants to all corners of the world, and endowing numerous programs in Japanology in the world\u27s best institutions of learning, Japanese companies have just uncovered a disconcerting truth: their competitors do not love them. Winning in global competition and being popular are clearly two different things
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