E-infrastructures fostering multi-centre collaborative research into the intensive care management of patients with brain injury

Clinical research is becoming ever more collaborative with multi-centre trials now a common practice. With this in mind, never has it been more important to have secure access to data and, in so doing, tackle the challenges of inter-organisational data access and usage. This is especially the case for research conducted within the brain injury domain due to the complicated multi-trauma nature of the disease with its associated complex collation of time-series data of varying resolution and quality. It is now widely accepted that advances in treatment within this group of patients will only be delivered if the technical infrastructures underpinning the collection and validation of multi-centre research data for clinical trials is improved. In recognition of this need, IT-based multi-centre e-Infrastructures such as the Brain Monitoring with Information Technology group (BrainIT - www.brainit.org) and Cooperative Study on Brain Injury Depolarisations (COSBID - www.cosbid.de) have been formed. A serious impediment to the effective implementation of these networks is access to the know-how and experience needed to install, deploy and manage security-oriented middleware systems that provide secure access to distributed hospital based datasets and especially the linkage of these data sets across sites. The recently funded EU framework VII ICT project Advanced Arterial Hypotension Adverse Event prediction through a Novel Bayesian Neural Network (AVERT-IT) is focused upon tackling these challenges. This chapter describes the problems inherent to data collection within the brain injury medical domain, the current IT-based solutions designed to address these problems and how they perform in practice. We outline how the authors have collaborated towards developing Grid solutions to address the major technical issues. Towards this end we describe a prototype solution which ultimately formed the basis for the AVERT-IT project. We describe the design of the underlying Grid infrastructure for AVERT-IT and how it will be used to produce novel approaches to data collection, data validation and clinical trial design is also presented

An Intelligent QoS Identification for Untrustworthy Web Services Via Two-phase Neural Networks

QoS identification for untrustworthy Web services is critical in QoS management in the service computing since the performance of untrustworthy Web services may result in QoS downgrade. The key issue is to intelligently learn the characteristics of trustworthy Web services from different QoS levels, then to identify the untrustworthy ones according to the characteristics of QoS metrics. As one of the intelligent identification approaches, deep neural network has emerged as a powerful technique in recent years. In this paper, we propose a novel two-phase neural network model to identify the untrustworthy Web services. In the first phase, Web services are collected from the published QoS dataset. Then, we design a feedforward neural network model to build the classifier for Web services with different QoS levels. In the second phase, we employ a probabilistic neural network (PNN) model to identify the untrustworthy Web services from each classification. The experimental results show the proposed approach has 90.5% identification ratio far higher than other competing approaches.Comment: 8 pages, 5 figure

Architecture and Implementation of a Trust Model for Pervasive Applications

Collaborative effort to share resources is a significant feature of pervasive computing environments. To achieve secure service discovery and sharing, and to distinguish between malevolent and benevolent entities, trust models must be defined. It is critical to estimate a device\u27s initial trust value because of the transient nature of pervasive smart space; however, most of the prior research work on trust models for pervasive applications used the notion of constant initial trust assignment. In this paper, we design and implement a trust model called DIRT. We categorize services in different security levels and depending on the service requester\u27s context information, we calculate the initial trust value. Our trust value is assigned for each device and for each service. Our overall trust estimation for a service depends on the recommendations of the neighbouring devices, inference from other service-trust values for that device, and direct trust experience. We provide an extensive survey of related work, and we demonstrate the distinguishing features of our proposed model with respect to the existing models. We implement a healthcare-monitoring application and a location-based service prototype over DIRT. We also provide a performance analysis of the model with respect to some of its important characteristics tested in various scenarios

Supporting security-oriented, inter-disciplinary research: crossing the social, clinical and geospatial domains

How many people have had a chronic disease for longer than 5-years in Scotland? How has this impacted upon their choices of employment? Are there any geographical clusters in Scotland where a high-incidence of patients with such long-term illness can be found? How does the life expectancy of such individuals compare with the national averages? Such questions are important to understand the health of nations and the best ways in which health care should be delivered and measured for their impact and success. In tackling such research questions, e-Infrastructures need to provide tailored, secure access to an extensible range of distributed resources including primary and secondary e-Health clinical data; social science data, and geospatial data sets amongst numerous others. In this paper we describe the security models underlying these e-Infrastructures and demonstrate their implementation in supporting secure, federated access to a variety of distributed and heterogeneous data sets exploiting the results of a variety of projects at the National e-Science Centre (NeSC) at the University of Glasgow

An adaptive trust based service quality monitoring mechanism for cloud computing

Cloud computing is the newest paradigm in distributed computing that delivers computing resources over the Internet as services. Due to the attractiveness of cloud computing, the market is currently flooded with many service providers. This has necessitated the customers to identify the right one meeting their requirements in terms of service quality. The existing monitoring of service quality has been limited only to quantification in cloud computing. On the other hand, the continuous improvement and distribution of service quality scores have been implemented in other distributed computing paradigms but not specifically for cloud computing. This research investigates the methods and proposes mechanisms for quantifying and ranking the service quality of service providers. The solution proposed in this thesis consists of three mechanisms, namely service quality modeling mechanism, adaptive trust computing mechanism and trust distribution mechanism for cloud computing. The Design Research Methodology (DRM) has been modified by adding phases, means and methods, and probable outcomes. This modified DRM is used throughout this study. The mechanisms were developed and tested gradually until the expected outcome has been achieved. A comprehensive set of experiments were carried out in a simulated environment to validate their effectiveness. The evaluation has been carried out by comparing their performance against the combined trust model and QoS trust model for cloud computing along with the adapted fuzzy theory based trust computing mechanism and super-agent based trust distribution mechanism, which were developed for other distributed systems. The results show that the mechanisms are faster and more stable than the existing solutions in terms of reaching the final trust scores on all three parameters tested. The results presented in this thesis are significant in terms of making cloud computing acceptable to users in verifying the performance of the service providers before making the selection

A Graph-Based Approach to Address Trust and Reputation in Ubiquitous Networks

The increasing popularity of virtual computing environments such as Cloud and Grid computing is helping to drive the realization of ubiquitous and pervasive computing. However, as computing becomes more entrenched in everyday life, the concepts of trust and risk become increasingly important. In this paper, we propose a new graph-based theoretical approach to address trust and reputation in complex ubiquitous networks. We formulate trust as a function of quality of a task and time required to authenticate agent-to-agent relationship based on the Zero-Common Knowledge (ZCK) authentication scheme. This initial representation applies a graph theory concept, accompanied by a mathematical formulation of trust metrics. The approach we propose increases awareness and trustworthiness to agents based on the values estimated for each requested task, we conclude by stating our plans for future work in this area

Intelligent XML Tag Classification Techniques for XML Encryption Improvement

Flexibility, friendliness, and adaptability have been key components to use XML to exchange information across different networks providing the needed common syntax for various messaging systems. However excess usage of XML as a communication medium shed the light on security standards used to protect exchanged messages achieving data confidentiality and privacy. This research presents a novel approach to secure XML messages being used in various systems with efficiency providing high security measures and high performance. system model is based on two major modules, the first to classify XML messages and define which parts of the messages to be secured assigning an importance level for each tag presented in XML message and then using XML encryption standard proposed earlier by W3C [3] to perform a partial encryption on selected parts defined in classification stage. As a result, study aims to improve both the performance of XML encryption process and bulk message handling to achieve data cleansing efficiently

Novel mechanism for evaluating feedback in the grid environment on resource allocation

The primary concern in proffering an infrastructure for general purpose computational grids formation is security. Grid implementations have been devised to deal with the security concerns. The chief factors that can be problematic in the secured selection of grid resources are the wide range of selection and the high degree of strangeness. Moreover, the lack of a higher degree of confidence relationship is likely to prevent efficient resource allocation and utilization. In this paper, we propose an efficient approach for the secured selection of grid resources, so as to achieve secure execution of the jobs. The presented approach utilizes trust and reputation for securely selecting the grid resources by also evaluation user’s feedback on the basis of the feedback already available about the entities. The proposed approach is scalable for an increased number of resources