Visual Quality Assessment and Blur Detection Based on the Transform of Gradient Magnitudes

abstract: Digital imaging and image processing technologies have revolutionized the way in which we capture, store, receive, view, utilize, and share images. In image-based applications, through different processing stages (e.g., acquisition, compression, and transmission), images are subjected to different types of distortions which degrade their visual quality. Image Quality Assessment (IQA) attempts to use computational models to automatically evaluate and estimate the image quality in accordance with subjective evaluations. Moreover, with the fast development of computer vision techniques, it is important in practice to extract and understand the information contained in blurred images or regions. The work in this dissertation focuses on reduced-reference visual quality assessment of images and textures, as well as perceptual-based spatially-varying blur detection. A training-free low-cost Reduced-Reference IQA (RRIQA) method is proposed. The proposed method requires a very small number of reduced-reference (RR) features. Extensive experiments performed on different benchmark databases demonstrate that the proposed RRIQA method, delivers highly competitive performance as compared with the state-of-the-art RRIQA models for both natural and texture images. In the context of texture, the effect of texture granularity on the quality of synthesized textures is studied. Moreover, two RR objective visual quality assessment methods that quantify the perceived quality of synthesized textures are proposed. Performance evaluations on two synthesized texture databases demonstrate that the proposed RR metrics outperforms full-reference (FR), no-reference (NR), and RR state-of-the-art quality metrics in predicting the perceived visual quality of the synthesized textures. Last but not least, an effective approach to address the spatially-varying blur detection problem from a single image without requiring any knowledge about the blur type, level, or camera settings is proposed. The evaluations of the proposed approach on a diverse sets of blurry images with different blur types, levels, and content demonstrate that the proposed algorithm performs favorably against the state-of-the-art methods qualitatively and quantitatively.Dissertation/ThesisDoctoral Dissertation Electrical Engineering 201

Analysis of Signal Decomposition and Stain Separation methods for biomedical applications

Nowadays, the biomedical signal processing and classification and medical image interpretation play an essential role in the detection and diagnosis of several human diseases. The problem of high variability and heterogeneity of information, which is extracted from digital data, can be addressed with signal decomposition and stain separation techniques which can be useful approaches to highlight hidden patterns or rhythms in biological signals and specific cellular structures in histological color images, respectively. This thesis work can be divided into two macro-sections. In the first part (Part I), a novel cascaded RNN model based on long short-term memory (LSTM) blocks is presented with the aim to classify sleep stages automatically. A general workflow based on single-channel EEG signals is developed to enhance the low performance in staging N1 sleep without reducing the performances in the other sleep stages (i.e. Wake, N2, N3 and REM). In the same context, several signal decomposition techniques and time-frequency representations are deployed for the analysis of EEG signals. All extracted features are analyzed by using a novel correlation-based timestep feature selection and finally the selected features are fed to a bidirectional RNN model. In the second part (Part II), a fully automated method named SCAN (Stain Color Adaptive Normalization) is proposed for the separation and normalization of staining in digital pathology. This normalization system allows to standardize digitally, automatically and in a few seconds, the color intensity of a tissue slide with respect to that of a target image, in order to improve the pathologist’s diagnosis and increase the accuracy of computer-assisted diagnosis (CAD) systems. Multiscale evaluation and multi-tissue comparison are performed for assessing the robustness of the proposed method. In addition, a stain normalization based on a novel mathematical technique, named ICD (Inverse Color Deconvolution) is developed for immunohistochemical (IHC) staining in histopathological images. In conclusion, the proposed techniques achieve satisfactory results compared to state-of-the-art methods in the same research field. The workflow proposed in this thesis work and the developed algorithms can be employed for the analysis and interpretation of other biomedical signals and for digital medical image analysis