Analysis of Unique Myoelectric Characteristics in Lower-Extremity Musculature During Locomotive State Transitions

Lower-extremity amputees face numerous challenges when returning to daily activities. Amongst these challenges is the ability to safely and dynamically transition from one locomotor state to another. Switching between level-ground, ramp, and stair locomotion poses an increased risk as lower-extremity functionality is compromised. Powered prosthetics have been proposed as a solution to this problem. Hypothetically, powered prosthetics would be able to return full functional to the amputated limb. The most common and successful source of information used in algorithms for lower-extremity prosthetics has been electromyography. However, in practice, amputees remain unable to easily actuate the mechanized joints of powered prostheses. Therefore, the current project aimed to identify myoelectric activation differences in lower-extremity musculature during the gait cycles preceding locomotor transition in able-bodied, trans-tibial, and trans-femoral subjects to assist efforts in developing robust classification algorithms for locomotor transitions. Analysis of electromyography was completed to determine if there were periods of activation where classification algorithms could utilize differences in myoelectric activation to appropriately control joint actuation in a subset of eight transitions that included level-ground locomotion and switching to either ramp or stair locomotion and vice versa. Ramp transitions were fundamentally similar to level-ground locomotion and elicited no differences in myoelectric activation. Stair transitions were found to alter muscle activation patterns in able-body and trans-tibial subjects. Trans-femoral subjects differentiated from able-bodied and trans-tibial subjects due to increased recruitment pattern variability. These patterns are distinct and may suggest individual learning patterns within the trans-femoral amputee population. Further investigation of these patterns may be warranted. Findings within able-bodied and trans-tibial subjects suggest common transition based differences within each respective population. Trans-tibial classification algorithms may be developed to utilize this information, using schemes that are focused on important areas during the gait cycle

Pattern classification of terrain during amputee walking

Thesis (Ph. D.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p. 113-116).In this thesis I study the role of extrinsic (sensors placed on the body) versus intrinsic sensing (instruments placed on an artificial limb) and determine a robust set of sensors from physical and reliability constraints for a terrain adaptation in a robotic ankle prosthesis. Further, during this thesis I collect a novel data-set that contains seven able-bodied participants walking over 19 terrain transitions and 7 non-amputees walking over 9 transitions, forming the largest collection of transitions to date using an exhaustive set of sensors: inertial measurement units, gyroscopes, kinematics from motion capture, and electromyography from 16 sites on the lower limbs for non-amputee subjects and 9 sites or amputee subjects. This work extends previous work [3] by using more conditions, a larger subject group, and more sensors on amputees, and includes non-amputees.I present a novel machine learning algorithm that uses sensor data during rapid transitions from pre-foothold to just prior to post-foothold to predict different terrain boundaries. This advances the field of biomechatronics, our understanding of terrain adaptation in people both with and without amputations, contributes to the development of a fully terrain adaptive robotic ankle prosthesis, and improves the quality of life for the physically challenged. Specifically we set out to prove between pre and post-foothold the ankle and knee positions calculated using an IMU attached to an amputees powered prosthetic ankle can discriminate with greater than 99% accuracy between 9 conditions. Our results suggest that myography as a non-volitional sensing modality for terrain adaptive prostheses was not needed.by Matthew Todd Farrell.Ph.D

Physical Behavior in Older Persons during Daily Life: Insights from Instrumented Shoes.

Activity level and gait parameters during daily life are important indicators for clinicians because they can provide critical insights into modifications of mobility and function over time. Wearable activity monitoring has been gaining momentum in daily life health assessment. Consequently, this study seeks to validate an algorithm for the classification of daily life activities and to provide a detailed gait analysis in older adults. A system consisting of an inertial sensor combined with a pressure sensing insole has been developed. Using an algorithm that we previously validated during a semi structured protocol, activities in 10 healthy elderly participants were recorded and compared to a wearable reference system over a 4 h recording period at home. Detailed gait parameters were calculated from inertial sensors. Dynamics of physical behavior were characterized using barcodes that express the measure of behavioral complexity. Activity classification based on the algorithm led to a 93% accuracy in classifying basic activities of daily life, i.e., sitting, standing, and walking. Gait analysis emphasizes the importance of metrics such as foot clearance in daily life assessment. Results also underline that measures of physical behavior and gait performance are complementary, especially since gait parameters were not correlated to complexity. Participants gave positive feedback regarding the use of the instrumented shoes. These results extend previous observations in showing the concurrent validity of the instrumented shoes compared to a body-worn reference system for daily-life physical behavior monitoring in older adults

Within-socket Myoelectric Prediction of Continuous Ankle Kinematics for Control of a Powered Transtibial Prosthesis

Objective. Powered robotic prostheses create a need for natural-feeling user interfaces and robust control schemes. Here, we examined the ability of a nonlinear autoregressive model to continuously map the kinematics of a transtibial prosthesis and electromyographic (EMG) activity recorded within socket to the future estimates of the prosthetic ankle angle in three transtibial amputees. Approach. Model performance was examined across subjects during level treadmill ambulation as a function of the size of the EMG sampling window and the temporal \u27prediction\u27 interval between the EMG/kinematic input and the model\u27s estimate of future ankle angle to characterize the trade-off between model error, sampling window and prediction interval. Main results. Across subjects, deviations in the estimated ankle angle from the actual movement were robust to variations in the EMG sampling window and increased systematically with prediction interval. For prediction intervals up to 150 ms, the average error in the model estimate of ankle angle across the gait cycle was less than 6°. EMG contributions to the model prediction varied across subjects but were consistently localized to the transitions to/from single to double limb support and captured variations from the typical ankle kinematics during level walking. Significance. The use of an autoregressive modeling approach to continuously predict joint kinematics using natural residual muscle activity provides opportunities for direct (transparent) control of a prosthetic joint by the user. The model\u27s predictive capability could prove particularly useful for overcoming delays in signal processing and actuation of the prosthesis, providing a more biomimetic ankle response

Sensor-Based Adaptive Control and Optimization of Lower-Limb Prosthesis.

Recent developments in prosthetics have enabled the development of powered prosthetic ankles (PPA). The advent of such technologies drastically improved impaired gait by increasing balance and reducing metabolic energy consumption by providing net positive power. However, control challenges limit performance and feasibility of today’s devices. With addition of sensors and motors, PPA systems should continuously make control decisions and adapt the system by manipulating control parameters of the prostheses. There are multiple challenges in optimization and control of PPAs. A prominent challenge is the objective setup of the system and calibration parameters to fit each subject. Another is whether it is possible to detect changes in intention and terrain before prosthetic use and how the system should react and adapt to it. In the first part of this study, a model for energy expenditure was proposed using electromyogram (EMG) signals from the residual lower-limbs PPA users. The proposed model was optimized to minimize energy expenditure. Optimization was performed using a modified Nelder-Mead approach with a Latin Hypercube sampling. Results of the proposed method were compared to expert values and it was shown to be a feasible alternative for tuning in a shorter time. In the second part of the study, the control challenges regarding lack of adaptivity for PPAs was investigated. The current PPA system used is enhanced with impedance-controlled parameters that allow the system to provide different assistance. However, current systems are set to a fixed value and fail to acknowledge various terrain and intentions throughout the day. In this study, a pseudo-real-time adaptive control system was proposed to predict the changes in the gait and provide a smoother gait. The proposed control system used physiological, kinetic, and kinematic data and fused them to predict the change. The prediction was done using machine learning-based methods. Results of the study showed an accuracy of up to 89.7 percent for prediction of change for four different cases

Sensor Fusion Representation of Locomotion Biomechanics with Applications in the Control of Lower Limb Prostheses

Free locomotion and movement in diverse environments are significant concerns for individuals with amputation who need independence in daily living activities. As users perform community ambulation, they face changing contexts that challenge what the typical passive prosthesis can offer. This problem rises opportunities for developing intelligent robotic systems that assist the locomotion with the least possible interruptions for direct input during operation. The use of multiple sensors to detect the user's intent and locomotion parameters is a promising technique that could provide a fast and natural response to the prostheses. However, the use of these sensors still requires a thorough investigation before they can be translated into practical settings. In addition, the dynamic change of context during locomotion should translate to adjustment in the device's response. To achieve the scaling rules for this modulation, a rich biomechanics dataset of community ambulation would provide a source of quantitative criteria to generate bioinspired controllers. This dissertation produces a better understanding of the characteristics of community ambulation from two different perspectives: the biomechanics of human motion and the sensory signals that can be captured by wearable technology. By studying human locomotion in diverse environments, including walking on stairs, ramps, and level ground, this work generated a comprehensive open-source dataset containing the biomechanics and signals from wearable sensors during locomotion, evaluating the effects of changing the locomotion context within the ambulation mode. With the multimodal dataset, I developed and evaluated a combined strategy for ambulation mode classification and the estimation of locomotion parameters, including the walking speed, stair height, ramp slope, and biological moment. Finally, by combining this knowledge and incorporating both the biomechanics insight with the machine learning-based inference in the frame of impedance control, I propose novel methods to improve the performance of lower-limb robotics with a focus on powered prostheses.Ph.D

Hybrid Volitional Control of a Robotic Transtibial Prosthesis using a Phase Variable Impedance Controller

For robotic transtibial prosthesis control, the global kinematics of the tibia can be used to monitor the progression of the gait cycle and command smooth and continuous actuation. In this work, these global tibia kinematics are used to define a phase variable impedance controller (PVIC), which is then implemented as the nonvolitional base controller within a hybrid volitional control framework (PVI-HVC). The gait progression estimation and biomechanic performance of one able-bodied individual walking on a robotic ankle prosthesis via a bypass adapter are compared for three control schemes: a passive benchmark controller, PVIC, and PVI-HVC. The different actuation of each controller had a direct effect on the global tibia kinematics, but the average deviation between the estimated and ground truth gait percentage were 1.6%, 1.8%, and 2.1%, respectively, for each controller. Both PVIC and PVI-HVC produced good agreement with able-bodied kinematic and kinetic references. As designed, PVI-HVC results were similar to those of PVIC when the user used low volitional intent, but yielded higher peak plantarflexion, peak torque, and peak power when the user commanded high volitional input in late stance. This additional torque and power also allowed the user to volitionally and continuously achieve activities beyond level walking, such as ascending ramps, avoiding obstacles, standing on tip-toes, and tapping the foot. In this way, PVI-HVC offers the kinetic and kinematic performance of the PVIC during level ground walking, along with the freedom to volitionally pursue alternative activities.Comment: 7 pages, 7 figures, submitted to ICRA 202

Instrumented shoes for daily activity monitoring in healthy and at risk populations

Daily activity reflects the health status of an individual. Ageing and disease drastically affect all dimensions of mobility, from the number of active bouts to their duration and intensity. Performing less activity leads to muscle deterioration and further weakness that could lead to increased fall risk. Gait performance is also affected by ageing and could be detrimental for daily mobility. Therefore, activity monitoring in older adults and at risk persons is crucial to obtain relevant quantitative information about daily life performance. Activity evaluation has mainly been established through questionnaires or daily logs. These methods are simple but not sufficiently accurate and are prone to errors. With the advent of microelectromechanical systems (MEMS), the availability of wearable sensors has shifted activity analysis towards ambulatory monitoring. In particular, inertial measurement units consisting of accelerometers and gyroscopes have shown to be extremely relevant for characterizing human movement. However, monitoring daily activity requires comfortable and easy to use systems that are strategically placed on the body or integrated in clothing to avoid movement hindrance. Several research based systems have employed multiple sensors placed at different locations, capable of recognizing activity types with high accuracy, but not comfortable for daily use. Single sensor systems have also been used but revealed inaccuracies in activity recognition. To this end, we propose an instrumented shoe system consisting of an inertial measurement unit and a pressure sensing insole with all the sensors placed at the shoe/foot level. By measuring the foot movement and loading, the recognition of locomotion and load bearing activities would be appropriate for activity classification. Furthermore, inertial measurement units placed on the foot can perform detailed gait analysis, providing the possibility of characterizing locomotion. The system and dedicated activity classification algorithms were first designed, tested and validated during the first part of the thesis. Their application to clinical rehabilitation of at risk persons was demonstrated over the second part. In the first part of the thesis, the designed instrumented shoes system was tested in standardized conditions with healthy elderly subjects performing a sequence of structured activities. An algorithm based on movement biomechanics was built to identify each activity, namely sitting, standing, level walking, stairs, ramps, and elevators. The rich array of sensors present in the system included a 3D accelerometer, 3D gyroscope, 8 force sensors, and a barometer allowing the algorithm to reach a high accuracy in classifying different activity types. The tuning parameters of the algorithm were shown to be robust to small changes, demonstrating the suitability of the algorithm to activity classification in older adults. Next, the system was tested in daily life conditions on the same elderly participants. Using a wearable reference system, the concurrent validity of the instrumented shoes in classifying daily activity was shown. Additionally, daily gait metrics were obtained and compared to the literature. Further insight into the relationship between some gait parameters as well as a global activity metric, the activity âcomplexityâ, was discussed. Participants positively rated their comfort while using the system... (Please refer to thesis for full abstract

Improving Intelligence of Robotic Lower-Limb Prostheses to Enhance Mobility for Individuals with Limb Loss

The field of wearable robotics is an emerging field that seeks to create smarter and intuitive devices that can assist users improve their overall quality of life. Specifically, individuals with lower limb amputation tend to have significantly impaired mobility and asymmetric gait patterns that result in increased energy expenditure than able-bodied individuals over a variety of tasks. Unfortunately, most of the commercial devices are passive and lack the ability to easily adapt to changing environmental contexts. Powered prostheses have shown promise to help restore the necessary power needed to walk in common ambulatory tasks. However, there is a need to infer/detect the user's movement to appropriately provide seamless and natural assistance. To achieve this behavior, a better understanding is required of adding intelligence to powered prostheses. This dissertation focuses on three key research objectives: 1) developing and enhancing offline intent recognition systems for both classification and regression tasks using embedded prosthetic mechanical sensors and machine learning, 2) deploying intelligent controllers in real-time to directly modulate assistive torque in a knee and ankle prosthetic device, and 3) quantifying the biomechanical and clinical effects of a powered prosthesis compared to a passive device. The findings conducted show improvement in developing powered prostheses to better enhance mobility for individuals with transfemoral amputation and show a step forward towards clinical acceptance.Ph.D