222 research outputs found
Generative agent-based architectural design computation : behavioral strategies for integrating material, fabrication and construction characteristics in design processes
The aim of this thesis is to investigate the generative potential of agent-based systems for integrating material and fabrication characteristics into design processes. This generative agent-based system reflects the significance of behavioral strategies in computational design and construction. This work presents a generative behavioral approach for integrating fabrication processes with material specifications. The development of a computational framework facilitates this integration via an agent-based system. A series of experiments with related case studies emphasizes behavioral strategies within the processes of formation and materialization.
This research proposes the integration of material and fabrication processes through an agent-based system. The utilization of this system reflects a theoretical framework in developing an integrative computational method. The implementation of this theoretical framework in practical studies demonstrates the applicability of this research. The practical developments highlight the importance of behavioral strategies to establish integral design computation.
Chapter 1 introduces the extended behavioral strategies to integration design. Chapter 2 provides a study about integrative design computation to abstract the main drivers of design integration through agent-based modeling. Chapter 3 presents agent-based systems in architectural design, specifically, in regards to material, fabricational, and environmental principles. Chapter 4 explores experiments and case studies to adjust the development of a generative agent-based system for integrating material and fabrication characteristics in design processes. Chapter 5 explains procedures for setting-up a generative agent-based design computation. Chapter 6 discusses the significance of behavioral strategies to develop different behavioral layers within a generative agent-based architectural design. Chapter 7 concludes the integral behavioral strategies by proposing trends to minimize the gap between formation and materialization through coalescing computational and physical agent-based systems.Ziel dieser Arbeit ist es, die generativen Potentiale von Agenten-basierten Systemen zur Integration von Material- und Fertigungseigenschaften im Entwurfsprozess zu untersuchen. Diese generative, Agenten-basierten Systeme spiegeln die Bedeutung von Regel- und Verhaltens-basierten Strategien für das digitale Entwerfen, Planen und Konstruieren wider. Die vorliegende Forschungsarbeit stellt einen generativen Ansatz zur Integration der Charakteristika von Material und Fertigung dar. Dies erfolgt über die Entwicklung einer digitalen Methode, die die Integration in ein Agent-basiertes System ermöglicht, was an einer Reihe von Experimenten und Fallstudien und der dazugehörigen Verhaltensstrategien für die Formgenerierung und Materialisierung erprobt wurde. Das operative Potential des theoretischen Rahmens wird in diesen praktischen Studien demonstriert und belegt die Anwendbarkeit der Forschung. Die theoretischen und praktischen Entwicklungen zeigen die Bedeutung von Verhaltensstrategien für das architektonische Entwerfen und einen ganzheitlichen digitalen Gestaltungs- und Bildungsprozess
Experimental and computational analysis of random cylinder packings with applications
Random cylinder packings are prevalent in chemical engineering applications and they can serve as prototype models of fibrous materials and/or other particulate materials. In this research, comprehensive studies on cylinder packings were carried out by computer simulations and by experiments. The computational studies made use of a collective rearrangement algorithm (based on a Monte Carlo technique) to generate different packing structures. 3D random packing limits were explored, and the packing structures were quantified by their positional ordering, orientational ordering, and the particle-particle contacts. Furthermore, the void space in the packings was expressed as a pore network, which retains topological and geometrical information. The significance of this approach is that any irregular continuous porous space can be approximated as a mathematically tractable pore network, thus allowing for efficient microscale flow simulation. Single-phase flow simulations were conducted, and the results were validated by calculating permeabilities. In the experimental part of the research, a series of densification experiments were conducted on equilateral cylinders. X-ray microtomography was used to image the cylinder packs, and the particle-scale packings were reconstructed from the digital data. This numerical approach makes it possible to study detailed packing structure, packing density, the onset of ordering, and wall effects. Orthogonal ordering and layered structures were found to exist at least two characteristic diameters from the wall in cylinder packings. Important applications for cylinder packings include multiphase flow in catalytic beds, heat transfer, bulk storage and transportation, and manufacturing of fibrous composites
Fluorescence Guided Tumor Imaging: Foundations for Translational Applications
Optical imaging for medical applications is a growing field, and it has the potential to improve medical outcomes through its increased sensitivity and specificity, lower cost, and small instrumentation footprint as compared to other imaging modalities. The method holds great promise, ranging from direct clinical use as a diagnostic or therapeutic tool, to pre-clinical applications for increased understanding of pathology. Additionally, optical imaging uses non-ionizing radiation which is safe for patients, so it can be used for repeated imaging procedures to monitor therapy, guide treatment, and provide real-time feedback. The versatile features of fluorescence-based optical imaging make it suited for cancer related imaging applications to increase patient survival and improve clinical outcomes. This dissertation focuses on the development of image processing methods to obtain semi-quantitative fluorescence imaging data. These methods allow for the standardization of fluorescence imaging data for tumor characterization.
When a fluorophore is located within tissue, changes in the fluorescence intensity can be used to isolate structures of interest. Typically, this is done through the accumulation of a dye in a target tissue either by the enhanced permeation and retention effect (EPR), or through targeted peptide sequences that bind receptors present in specific tissue types. When imaged, the contrast generated by a fluorescent probe can be used to indicate the presence or absence of a structure, bio-chemical compound, or receptor. Fluorescence intensity contrast can answer many biological and clinical questions effectively; however, we were interested in analyzing more than solely contrast when using planar fluorescence imaging.
To better understand tumor properties, we developed a series of algorithms that harness additional pieces of information present in the fluorescence signal. We demonstrated that adding novel image processing algorithms enhanced the knowledge obtained from planar fluorescence images. Through this work, we gained an understanding of alternative approaches for processing planar fluorescence imaging data with the goal of improving future cancer diagnostics and therapeutics
Development Of A High Performance Mosaicing And Super-Resolution Algorithm
In this dissertation, a high-performance mosaicing and super-resolution algorithm is described. The scale invariant feature transform (SIFT)-based mosaicing algorithm builds an initial mosaic which is iteratively updated by the robust super resolution algorithm to achieve the final high-resolution mosaic. Two different types of datasets are used for testing: high altitude balloon data and unmanned aerial vehicle data. To evaluate our algorithm, five performance metrics are employed: mean square error, peak signal to noise ratio, singular value decomposition, slope of reciprocal singular value curve, and cumulative probability of blur detection. Extensive testing shows that the proposed algorithm is effective in improving the captured aerial data and the performance metrics are accurate in quantifying the evaluation of the algorithm
A Modular Approach to Lung Nodule Detection from Computed Tomography Images Using Artificial Neural Networks and Content Based Image Representation
Lung cancer is one of the most lethal cancer types. Research in computer aided detection (CAD) and diagnosis for lung cancer aims at providing effective tools to assist physicians in cancer diagnosis and treatment to save lives. In this dissertation, we focus on developing a CAD framework for automated lung cancer nodule detection from 3D lung computed tomography (CT) images. Nodule detection is a challenging task that no machine intelligence can surpass human capability to date. In contrast, human recognition power is limited by vision capacity and may suffer from work overload and fatigue, whereas automated nodule detection systems can complement expert’s efforts to achieve better detection performance. The proposed CAD framework encompasses several desirable properties such as mimicking physicians by means of geometric multi-perspective analysis, computational efficiency, and the most importantly producing high performance in detection accuracy. As the central part of the framework, we develop a novel hierarchical modular decision engine implemented by Artificial Neural Networks. One advantage of this decision engine is that it supports the combination of spatial-level and feature-level information analysis in an efficient way. Our methodology overcomes some of the limitations of current lung nodule detection techniques by combining geometric multi-perspective analysis with global and local feature analysis. The proposed modular decision engine design is flexible to modifications in the decision modules; the engine structure can adopt the modifications without having to re-design the entire system. The engine can easily accommodate multi-learning scheme and parallel implementation so that each information type can be processed (in parallel) by the most adequate learning technique of its own. We have also developed a novel shape representation technique that is invariant under rigid-body transformation and we derived new features based on this shape representation for nodule detection. We implemented a prototype nodule detection system as a demonstration of the proposed framework. Experiments have been conducted to assess the performance of the proposed methodologies using real-world lung CT data. Several performance measures for detection accuracy are used in the assessment. The results show that the decision engine is able to classify patterns efficiently with very good classification performance
A comparative evaluation for liver segmentation from spir images and a novel level set method using signed pressure force function
Thesis (Doctoral)--Izmir Institute of Technology, Electronics and Communication Engineering, Izmir, 2013Includes bibliographical references (leaves: 118-135)Text in English; Abstract: Turkish and Englishxv, 145 leavesDeveloping a robust method for liver segmentation from magnetic resonance images is a challenging task due to similar intensity values between adjacent organs, geometrically complex liver structure and injection of contrast media, which causes all tissues to have different gray level values. Several artifacts of pulsation and motion, and partial volume effects also increase difficulties for automatic liver segmentation from magnetic resonance images. In this thesis, we present an overview about liver segmentation methods in magnetic resonance images and show comparative results of seven different liver segmentation approaches chosen from deterministic (K-means based), probabilistic (Gaussian model based), supervised neural network (multilayer perceptron based) and deformable model based (level set) segmentation methods. The results of qualitative and quantitative analysis using sensitivity, specificity and accuracy metrics show that the multilayer perceptron based approach and a level set based approach which uses a distance regularization term and signed pressure force function are reasonable methods for liver segmentation from spectral pre-saturation inversion recovery images. However, the multilayer perceptron based segmentation method requires a higher computational cost. The distance regularization term based automatic level set method is very sensitive to chosen variance of Gaussian function. Our proposed level set based method that uses a novel signed pressure force function, which can control the direction and velocity of the evolving active contour, is faster and solves several problems of other applied methods such as sensitivity to initial contour or variance parameter of the Gaussian kernel in edge stopping functions without using any regularization term
Geometric data understanding : deriving case specific features
There exists a tradition using precise geometric modeling, where uncertainties in data can be considered noise. Another tradition relies on statistical nature of vast quantity of data, where geometric regularity is intrinsic to data and statistical models usually grasp this level only indirectly. This work focuses on point cloud data of natural resources and the silhouette recognition from video input as two real world examples of problems having geometric content which is intangible at the raw data presentation.
This content could be discovered and modeled to some degree by such machine learning (ML) approaches like deep learning, but either a direct coverage of geometry in samples or addition of special geometry invariant layer is necessary. Geometric content is central when there is a need for direct observations of spatial variables, or one needs to gain a mapping to a geometrically consistent data representation, where e.g. outliers or noise can be easily discerned.
In this thesis we consider transformation of original input data to a geometric feature space in two example problems. The first example is curvature of surfaces, which has met renewed interest since the introduction of ubiquitous point cloud data and the maturation of the discrete differential geometry. Curvature spectra can characterize a spatial sample rather well, and provide useful features for ML purposes. The second example involves projective methods used to video stereo-signal analysis in swimming analytics.
The aim is to find meaningful local geometric representations for feature generation, which also facilitate additional analysis based on geometric understanding of the model. The features are associated directly to some geometric quantity, and this makes it easier to express the geometric constraints in a natural way, as shown in the thesis. Also, the visualization and further feature generation is much easier. Third, the approach provides sound baseline methods to more traditional ML approaches, e.g. neural network methods. Fourth, most of the ML methods can utilize the geometric features presented in this work as additional features.Geometriassa käytetään perinteisesti tarkkoja malleja, jolloin datassa esiintyvät epätarkkuudet edustavat melua. Toisessa perinteessä nojataan suuren datamäärän tilastolliseen luonteeseen, jolloin geometrinen säännönmukaisuus on datan sisäsyntyinen ominaisuus, joka hahmotetaan tilastollisilla malleilla ainoastaan epäsuorasti. Tämä työ keskittyy kahteen esimerkkiin: luonnonvaroja kuvaaviin pistepilviin ja videohahmontunnistukseen. Nämä ovat todellisia ongelmia, joissa geometrinen sisältö on tavoittamattomissa raakadatan tasolla.
Tämä sisältö voitaisiin jossain määrin löytää ja mallintaa koneoppimisen keinoin, esim. syväoppimisen avulla, mutta joko geometria pitää kattaa suoraan näytteistämällä tai tarvitaan neuronien lisäkerros geometrisia invariansseja varten. Geometrinen sisältö on keskeinen, kun tarvitaan suoraa avaruudellisten suureiden havainnointia, tai kun tarvitaan kuvaus geometrisesti yhtenäiseen dataesitykseen, jossa poikkeavat näytteet tai melu voidaan helposti erottaa.
Tässä työssä tarkastellaan datan muuntamista geometriseen piirreavaruuteen kahden esimerkkiohjelman suhteen. Ensimmäinen esimerkki on pintakaarevuus, joka on uudelleen virinneen kiinnostuksen kohde kaikkialle saatavissa olevan datan ja diskreetin geometrian kypsymisen takia. Kaarevuusspektrit voivat luonnehtia avaruudellista kohdetta melko hyvin ja tarjota koneoppimisessa hyödyllisiä piirteitä. Toinen esimerkki koskee projektiivisia menetelmiä käytettäessä stereovideosignaalia uinnin analytiikkaan.
Tavoite on löytää merkityksellisiä paikallisen geometrian esityksiä, jotka samalla mahdollistavat muun geometrian ymmärrykseen perustuvan analyysin. Piirteet liittyvät suoraan johonkin geometriseen suureeseen, ja tämä helpottaa luonnollisella tavalla geometristen rajoitteiden käsittelyä, kuten väitöstyössä osoitetaan. Myös visualisointi ja lisäpiirteiden luonti muuttuu helpommaksi. Kolmanneksi, lähestymistapa suo selkeän vertailumenetelmän perinteisemmille koneoppimisen lähestymistavoille, esim. hermoverkkomenetelmille. Neljänneksi, useimmat koneoppimismenetelmät voivat hyödyntää tässä työssä esitettyjä geometrisia piirteitä lisäämällä ne muiden piirteiden joukkoon
Model-Based Environmental Visual Perception for Humanoid Robots
The visual perception of a robot should answer two fundamental questions: What? and Where? In order to properly and efficiently reply to these questions, it is essential to establish a bidirectional coupling between the external stimuli and the internal representations. This coupling links the physical world with the inner abstraction models by sensor transformation, recognition, matching and optimization algorithms. The objective of this PhD is to establish this sensor-model coupling
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A novel musculoskeletal joint modelling for orthopaedic applications
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University.The objective of the work carried out in this thesis was to develop analytical and
computational tools to model and investigate musculoskeletal human joints. It was
recognised that the FEA was used by many researchers in modelling human
musculoskeletal motion, loading and stresses. However the continuum mechanics
played only a minor role in determining the articular joint motion, and its value was
questionable. This is firstly due to the computational cost and secondly due to its
impracticality for this application. On the other hand, there isn’t any suitable software
for precise articular joint motion analysis to deal with the local joint stresses or non
standard joints. The main requirement in orthopaedics field is to develop a modeller
software (and its associated theories) to model anatomic joint as it is, without any
simplification with respect to joint surface morphology and material properties of
surrounding tissues. So that the proposed modeller can be used for evaluating and
diagnosing different joint abnormalities but furthermore form the basis for performing
implant insertion and analysis of the artificial joints. The work which is presented in this thesis is a new frame work and has been developed for human anatomic joint analysis which describes the joint in terms of its surface geometry and surrounding
musculoskeletal tissues. In achieving such a framework several contributions were
made to the 6DOF linear and nonlinear joint modelling, the mathematical definition of
joint stiffness, tissue path finding and wrapping and the contact with collision analysis. In 6DOF linear joint modelling, the contribution is the development of joint stiffness and damping matrices. This modelling approach is suitable for the linear range of tissue stiffness and damping properties. This is the first of its kind and it gives a firm analytical basis for investigating joints with surrounding tissue and the cartilage. The 6DOF nonlinear joint modelling is a new scheme which is described for modelling the motion of multi bodies joined by non-linear stiffness and contact elements. The proposed method requires no matrix assembly for the stiffness and damping elements or mass elements. The novelty in the nonlinear modelling, relates to the overall algorithmic approach and handling local non-linearity by procedural means. The mathematical definition of joint stiffness is also a new proposal which is based on the mathematical definition of stiffness between two bodies. Based on the joint stiffness matrix properties, number of joint stiffness invariants was obtained analytically such as the centre of stiffness, the principal translational stiffnesses, and the principal rotational stiffnesses. In corresponding to these principal stiffnesses, their principal axes have been also obtained. Altogether, a joint is assessed by six principal axes and six principal stiffnesses and its centre of stiffness. These formulations are new and show that a joint can be described in terms of inherent stiffness properties. It is expected that these will be better in characterising a joint in comparison to laxity based characterisation. The
development of tissue path finding and wrapping algorithms are also introduced as new approaches. The musculoskeletal tissue wrapping involves calculating the shortest
distance between two points on a meshed surface. A new heuristic algorithm was
proposed. The heuristic is based on minimising the accumulative divergence from the straight line between two points on the surface and the direction of travel on the surface (i.e. bone). In contact and collision based development, the novel algorithm has been proposed that detects possible colliding points on the motion trajectory by redefining the distance as a two dimensional measure along the velocity approach vector and perpendicular to this vector. The perpendicular distance determines if there are potentially colliding points, and the distance along the velocity determines how close they are. The closest pair among the potentially colliding points gives the “time to collision”. The algorithm can eliminate the “fly pass” situation where very close points may not collide because of the direction of their relative velocity. All these developed
algorithms and modelling theories, have been encompassed in the developed prototype
software in order to simulate the anatomic joint articulations through modelling
formulations developed. The software platform provides a capability for analysing joints as 6DOF joints based on anatomic joint surfaces. The software is highly interactive and driven by well structured database, designed to be highly flexible for the future developments. Particularly, two case studies are carried out in this thesis in order to generate results relating to all the proposed elements of the study. The results obtained from the case studies show good agreement with previously published results or model based results obtained from Lifemod software, whenever comparison was possible. In some cases the comparison was not possible because there were no equivalent results; the results were supported by other indicators. The modelling based results were also supported by experiments performed in the Brunel Orthopaedic Research and Learning
Centre
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