Spike sorting for large, dense electrode arrays

Developments in microfabrication technology have enabled the production of neural electrode arrays with hundreds of closely spaced recording sites, and electrodes with thousands of sites are under development. These probes in principle allow the simultaneous recording of very large numbers of neurons. However, use of this technology requires the development of techniques for decoding the spike times of the recorded neurons from the raw data captured from the probes. Here we present a set of tools to solve this problem, implemented in a suite of practical, user-friendly, open-source software. We validate these methods on data from the cortex, hippocampus and thalamus of rat, mouse, macaque and marmoset, demonstrating error rates as low as 5%

Distributed Detection over Fading MACs with Multiple Antennas at the Fusion Center

A distributed detection problem over fading Gaussian multiple-access channels is considered. Sensors observe a phenomenon and transmit their observations to a fusion center using the amplify and forward scheme. The fusion center has multiple antennas with different channel models considered between the sensors and the fusion center, and different cases of channel state information are assumed at the sensors. The performance is evaluated in terms of the error exponent for each of these cases, where the effect of multiple antennas at the fusion center is studied. It is shown that for zero-mean channels between the sensors and the fusion center when there is no channel information at the sensors, arbitrarily large gains in the error exponent can be obtained with sufficient increase in the number of antennas at the fusion center. In stark contrast, when there is channel information at the sensors, the gain in error exponent due to having multiple antennas at the fusion center is shown to be no more than a factor of (8/pi) for Rayleigh fading channels between the sensors and the fusion center, independent of the number of antennas at the fusion center, or correlation among noise samples across sensors. Scaling laws for such gains are also provided when both sensors and antennas are increased simultaneously. Simple practical schemes and a numerical method using semidefinite relaxation techniques are presented that utilize the limited possible gains available. Simulations are used to establish the accuracy of the results.Comment: 21 pages, 9 figures, submitted to the IEEE Transactions on Signal Processin

Low-Complexity Detection/Equalization in Large-Dimension MIMO-ISI Channels Using Graphical Models

In this paper, we deal with low-complexity near-optimal detection/equalization in large-dimension multiple-input multiple-output inter-symbol interference (MIMO-ISI) channels using message passing on graphical models. A key contribution in the paper is the demonstration that near-optimal performance in MIMO-ISI channels with large dimensions can be achieved at low complexities through simple yet effective simplifications/approximations, although the graphical models that represent MIMO-ISI channels are fully/densely connected (loopy graphs). These include 1) use of Markov Random Field (MRF) based graphical model with pairwise interaction, in conjunction with {\em message/belief damping}, and 2) use of Factor Graph (FG) based graphical model with {\em Gaussian approximation of interference} (GAI). The per-symbol complexities are $O(K^2n_t^2)$ and $O(Kn_t)$ for the MRF and the FG with GAI approaches, respectively, where $K$ and $n_t$ denote the number of channel uses per frame, and number of transmit antennas, respectively. These low-complexities are quite attractive for large dimensions, i.e., for large $Kn_t$. From a performance perspective, these algorithms are even more interesting in large-dimensions since they achieve increasingly closer to optimum detection performance for increasing $Kn_t$. Also, we show that these message passing algorithms can be used in an iterative manner with local neighborhood search algorithms to improve the reliability/performance of $M$-QAM symbol detection

Hybrid Analog-Digital Precoding for Interference Exploitation

We study the multi-user massive multiple-input-single-output (MISO) and focus on the downlink systems where the base station (BS) employs hybrid analog-digital precoding with low-cost 1-bit digital-to-analog converters (DACs). In this paper, we propose a hybrid downlink transmission scheme where the analog precoder is formed based on the SVD decomposition. In the digital domain, instead of designing a linear transmit precoding matrix, we directly design the transmit signals by exploiting the concept of constructive interference. The optimization problem is then formulated based on the geometry of the modulation constellations and is shown to be non-convex. We relax the above optimization and show that the relaxed optimization can be transformed into a linear programming that can be efficiently solved. Numerical results validate the superiority of the proposed scheme for the hybrid massive MIMO downlink systems.Comment: 5 pages, EUSIPCO 201