5 research outputs found

    Analyzing fibrous tissue pattern in fibrous dysplasia bone images using deep R-CNN networks for segmentation

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    Predictive health monitoring systems help to detect human health threats in the early stage. Evolving deep learning techniques in medical image analysis results in efficient feedback in quick time. Fibrous dysplasia (FD) is a genetic disorder, triggered by the mutation in Guanine Nucleotide binding protein with alpha stimulatory activities in the human bone genesis. It slowly occupies the bone marrow and converts the bone cell into fibrous tissues. It weakens the bone structure and leads to permanent disability. This paper proposes the study of FD bone image analyzing techniques with deep networks. Also, the linear regression model is annotated for predicting the bone abnormality levels with observed coefficients. Modern image processing begins with various image filters. It describes the edges, shades, texture values of the receptive field. Different types of segmentation and edge detection mechanisms are applied to locate the tumor, lesion, and fibrous tissues in the bone image. Extract the fibrous region in the bone image using the region-based convolutional neural network algorithm. The segmented results are compared with their accuracy metrics. The segmentation loss is reduced by each iteration. The overall loss is 0.24% and the accuracy is 99%, segmenting the masked region produces 98% of accuracy, and building the bounding boxes is 99% of accuracy

    A New Ensemble Classification System For Fracture Zone Prediction Using Imbalanced Micro-CT Bone Morphometrical Data

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    Smoking and Second Hand Smoking in Adolescents with Chronic Kidney Disease: A Report from the Chronic Kidney Disease in Children (CKiD) Cohort Study

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    The goal of this study was to determine the prevalence of smoking and second hand smoking [SHS] in adolescents with CKD and their relationship to baseline parameters at enrollment in the CKiD, observational cohort study of 600 children (aged 1-16 yrs) with Schwartz estimated GFR of 30-90 ml/min/1.73m2. 239 adolescents had self-report survey data on smoking and SHS exposure: 21 [9%] subjects had “ever” smoked a cigarette. Among them, 4 were current and 17 were former smokers. Hypertension was more prevalent in those that had “ever” smoked a cigarette (42%) compared to non-smokers (9%), p\u3c0.01. Among 218 non-smokers, 130 (59%) were male, 142 (65%) were Caucasian; 60 (28%) reported SHS exposure compared to 158 (72%) with no exposure. Non-smoker adolescents with SHS exposure were compared to those without SHS exposure. There was no racial, age, or gender differences between both groups. Baseline creatinine, diastolic hypertension, C reactive protein, lipid profile, GFR and hemoglobin were not statistically different. Significantly higher protein to creatinine ratio (0.90 vs. 0.53, p\u3c0.01) was observed in those exposed to SHS compared to those not exposed. Exposed adolescents were heavier than non-exposed adolescents (85th percentile vs. 55th percentile for BMI, p\u3c 0.01). Uncontrolled casual systolic hypertension was twice as prevalent among those exposed to SHS (16%) compared to those not exposed to SHS (7%), though the difference was not statistically significant (p= 0.07). Adjusted multivariate regression analysis [OR (95% CI)] showed that increased protein to creatinine ratio [1.34 (1.03, 1.75)] and higher BMI [1.14 (1.02, 1.29)] were independently associated with exposure to SHS among non-smoker adolescents. These results reveal that among adolescents with CKD, cigarette use is low and SHS is highly prevalent. The association of smoking with hypertension and SHS with increased proteinuria suggests a possible role of these factors in CKD progression and cardiovascular outcomes

    Multimetal smithing : An urban craft in rural settings?

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    Multimetal smithing should be defined as the use of more than one metal and/or different metalworking techniques within thesame crafts-milieu. This complex metalworking has long been linked to centrality, central places and urbanity in Scandinavia.It has been extensively argued that fine casting and smithing, as well as manufacture utilizing precious metals was exclusivelyundertaken within early urban settings or the “central places” pre-dating these. Furthermore, the presence of complex metalcraftsmanship has been used as a driving indicator of the political, social and economic superiority of certain sites, therebyenhancing their identity as “centralities”.Recent research has come to challenge the universality of this link between urbanity, centrality and complex metalworkingas sites in rural settings with evidence of multimetal smithing are being identified. This shows that the relationship between thecraft and centrality (urbanity) must be nuanced and that perhaps multimetal craftsmanship should be reconsidered as an urbanindicator.The thesis project “From Crucible and onto Anvil” started in 2015 and focuses on sites housing remains of multimetalcraftsmanship dating primarily from 500-1000 AD. Within the project a comprehensive survey of sites will be used to evaluate thepresence of multimetal craftsmanship in the landscape. Sites in selected target areas will also be subject to intra-site analysisfocusing on workshop organisation, production output, metalworking techniques and chronological variances.A key aim in the project is to elucidate the conceptual aspects of complex metalworking. The term multimetality is used toanalytically frame all the societal and economic aspects of multimetal craftsmanship. Through this inclusive perspective both thecraftsmanship and the metalworkers behind it are positioned within the overall socioeconomic framework. The metalworkers,their skills and competences as well as the products of their labour are viewed as dynamic actors in the landscape and on thearenas of political economy of the Late Iron Age.The survey has already revealed interesting aspects concerning multimetal smithing and urbanity. Although the multimetalsites do cluster against areas of early urban development there are also other patterns emerging. Multimetal craftsmanship – both as practice and concept – was well represented in both rural peripheral settings and urban crafts-milieus. This means that therole of multimetality as part of an “urban conceptual package” is crucial to investigate. Such an approach will have the dual endsof properly understanding the craft and its societal implications, but also further the knowledge of the phenomenon of urbanityas a whole. Was multimetal smithing part of an “urban package” that spread into the rural landscape? Did the multimetality differbetween urban and rural crafts-milieus? How does early urbanity relate to the chronology of multimetal craftsmanship?This paper aims to counter these questions using examples from the survey of multimetal sites conducted within the thesisproject. A comparison between selected sites will be presented. The purpose of this is to evaluate the role of multimetality withinthe “urban package” and discuss the role of complex metalworking in the establishment of urban arenas of interaction in LateIron Age Scandinavia
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