A New Approach for Model-Based Adaptive Region Growing in Medical Image Analysis

Interaction increases flexibility of segmentation but it leads to undesirable behaviour of an algorithm if knowledge being requested is inappropriate

Image Segmentation with Multidimensional Refinement Indicators

We transpose an optimal control technique to the image segmentation problem. The idea is to consider image segmentation as a parameter estimation problem. The parameter to estimate is the color of the pixels of the image. We use the adaptive parameterization technique which builds iteratively an optimal representation of the parameter into uniform regions that form a partition of the domain, hence corresponding to a segmentation of the image. We minimize an error function during the iterations, and the partition of the image into regions is optimally driven by the gradient of this error. The resulting segmentation algorithm inherits desirable properties from its optimal control origin: soundness, robustness, and flexibility

Automated detection of brain abnormalities in neonatal hypoxia ischemic injury from MR images.

We compared the efficacy of three automated brain injury detection methods, namely symmetry-integrated region growing (SIRG), hierarchical region splitting (HRS) and modified watershed segmentation (MWS) in human and animal magnetic resonance imaging (MRI) datasets for the detection of hypoxic ischemic injuries (HIIs). Diffusion weighted imaging (DWI, 1.5T) data from neonatal arterial ischemic stroke (AIS) patients, as well as T2-weighted imaging (T2WI, 11.7T, 4.7T) at seven different time-points (1, 4, 7, 10, 17, 24 and 31 days post HII) in rat-pup model of hypoxic ischemic injury were used to assess the temporal efficacy of our computational approaches. Sensitivity, specificity, and similarity were used as performance metrics based on manual ('gold standard') injury detection to quantify comparisons. When compared to the manual gold standard, automated injury location results from SIRG performed the best in 62% of the data, while 29% for HRS and 9% for MWS. Injury severity detection revealed that SIRG performed the best in 67% cases while 33% for HRS. Prior information is required by HRS and MWS, but not by SIRG. However, SIRG is sensitive to parameter-tuning, while HRS and MWS are not. Among these methods, SIRG performs the best in detecting lesion volumes; HRS is the most robust, while MWS lags behind in both respects

Medical imaging analysis with artificial neural networks

Given that neural networks have been widely reported in the research community of medical imaging, we provide a focused literature survey on recent neural network developments in computer-aided diagnosis, medical image segmentation and edge detection towards visual content analysis, and medical image registration for its pre-processing and post-processing, with the aims of increasing awareness of how neural networks can be applied to these areas and to provide a foundation for further research and practical development. Representative techniques and algorithms are explained in detail to provide inspiring examples illustrating: (i) how a known neural network with fixed structure and training procedure could be applied to resolve a medical imaging problem; (ii) how medical images could be analysed, processed, and characterised by neural networks; and (iii) how neural networks could be expanded further to resolve problems relevant to medical imaging. In the concluding section, a highlight of comparisons among many neural network applications is included to provide a global view on computational intelligence with neural networks in medical imaging

Image segmentation with adaptive region growing based on a polynomial surface model

A new method for segmenting intensity images into smooth surface segments is presented. The main idea is to divide the image into flat, planar, convex, concave, and saddle patches that coincide as well as possible with meaningful object features in the image. Therefore, we propose an adaptive region growing algorithm based on low-degree polynomial fitting. The algorithm uses a new adaptive thresholding technique with the L∞ fitting cost as a segmentation criterion. The polynomial degree and the fitting error are automatically adapted during the region growing process. The main contribution is that the algorithm detects outliers and edges, distinguishes between strong and smooth intensity transitions and finds surface segments that are bent in a certain way. As a result, the surface segments corresponding to meaningful object features and the contours separating the surface segments coincide with real-image object edges. Moreover, the curvature-based surface shape information facilitates many tasks in image analysis, such as object recognition performed on the polynomial representation. The polynomial representation provides good image approximation while preserving all the necessary details of the objects in the reconstructed images. The method outperforms existing techniques when segmenting images of objects with diffuse reflecting surfaces