Neurocognitive impairment is associated with lower health literacy among persons living with HIV infection.

This study sought to determine the effects of HIV-associated neurocognitive disorders (HAND) on health literacy, which encompasses the ability to access, understand, appraise, and apply health-related information. Participants included 56 HIV seropositive individuals, 24 of whom met Frascati criteria for HAND, and 24 seronegative subjects who were comparable on age, education, ethnicity, and oral word reading. Each participant was administered a brief battery of well-validated measures of health literacy, including the Expanded Numeracy Scale (ENS), Newest Vital Sign (NVS), Rapid Estimate of Adult Literacy in Medicine (REALM), and Brief Health Literacy Screen (BHLS). Results revealed significant omnibus differences on the ENS and NVS, which were driven by poorer performance in the HAND group. There were no significant differences on the REALM or the BHLS by HAND status. Among individuals with HAND, lower scores on the NVS were associated with greater severity of neurocognitive dysfunction (e.g., working memory and verbal fluency) and self-reported dependence in activities of daily living. These preliminary findings suggest that HAND hinders both fundamental (i.e., basic knowledge, such as numeracy) and critical (i.e., comprehension and application of healthcare information) health literacy capacities, and therefore may be an important factor in the prevalence of health illiteracy. Health literacy-focused intervention may play an important role in the treatment and health trajectories among persons living with HIV infection

Tecnologia assistiva para crianças com transtorno do espectro autista que vivenciam estresse e ansiedade

With the development of current technology and influences that have been made by the Industry 4.0 utilizing ICTs, IoT, smart systems and products and many others, Assistive Technology (AT) is an important and integral part of the daily life of many people who experience disabilities. Autism Spectrum Disorder (ASD) is a special category of disorder that can greatly benefit from its use. The purpose of this research is to collect data of Assistive Technology aimed at the detection, prevention and improvement of anxiety and stress (a characteristic of which has been proven to exist and is expressed in various ways in people with ASD). In the introduction, basic definitions regarding the neurobiology of stress and ASD are analyzed. In the main part AT, stress and anxiety correlations are made with ASD and AT devices are described and documented regarding their use for anxiety and stress in children and adolescents with ASD. The Assistive equipment and devices are divided into 2 main categories, 1) Low-tech and 2) Mid-High tech. The results of the research reveal a significant research gap in the use of AT to combat stress and anxiety and the difficulty of many promising options (especially in the domain of Mid-High tech) to be an easy and economical solution in integrating them into the daily life of people with ASD.Con el desarrollo de la tecnología actual y las influencias que ha tenido la Industria 4.0 utilizando TIC, IoT, sistemas y productos inteligentes y muchos otros, la Tecnología de asistencia (TA) es una parte importante e integral de la vida diaria de muchas personas que sufren de discapacidad. . . El trastorno del espectro autista (TEA) es una categoría especial de trastorno que puede beneficiarse enormemente de su uso. El objetivo de esta investigación es recopilar datos de Tecnología Asistiva dirigidos a detectar, prevenir y mejorar la ansiedad y el estrés (una característica que está comprobada y se expresa de diferentes formas en las personas con TEA). En la introducción se analizan definiciones básicas sobre la neurobiología del estrés y el TEA. En su mayor parte se realizan correlaciones de TA, estrés y ansiedad con los TEA y se describen y documentan los dispositivos de TA en relación a su uso para la ansiedad y el estrés en niños y adolescentes con TEA. Los equipos y dispositivos de asistencia se dividen en 2 categorías principales, 1) Tecnología baja y 2) Tecnología media-alta. Los resultados de la encuesta revelan una importante brecha de investigación en el uso de TA para combatir el estrés y la ansiedad y la dificultad de que muchas opciones prometedoras (especialmente en el dominio tecnológico medio-alto) sean una solución fácil y rentable para integrarlas en la vida cotidiana. de personas con TEA.Com o desenvolvimento da tecnologia atual e as influências que foram feitas pela Indústria 4.0 utilizando TICs, IoT, sistemas e produtos inteligentes e muitos outros, a Tecnologia Assistiva (TA) é uma parte importante e integrante da vida diária de muitas pessoas que sofrem de deficiência. O Transtorno do Espectro do Autismo (TEA) é uma categoria especial de transtorno que pode se beneficiar muito com seu uso. O objetivo desta pesquisa é coletar dados de Tecnologia Assistiva voltados para a detecção, prevenção e melhora da ansiedade e do estresse (característica que comprovadamente existe e se expressa de diversas formas em pessoas com TEA). Na introdução, são analisadas definições básicas sobre a neurobiologia do estresse e do TEA. Na parte principal, são feitas correlações de TA, estresse e ansiedade com ASD e dispositivos de TA são descritos e documentados em relação ao seu uso para ansiedade e estresse em crianças e adolescentes com TEA. Os equipamentos e dispositivos assistivos são divididos em 2 categorias principais, 1) Low-tech e 2) Mid-High tech. Os resultados da pesquisa revelam uma lacuna significativa de pesquisa no uso de TA para combater o estresse e a ansiedade e a dificuldade de muitas opções promissoras (especialmente no domínio da tecnologia média-alta) serem uma solução fácil e econômica em integrá-las ao cotidiano de pessoas com TEA

Neurocognition and behaviour:diagnostic work-up and interventions in Duchenne and Becker muscular dystrophy

Duchenne (DMD) and Becker (BMD) Muscular Dystrophy are hereditary, progressive muscle diseases caused by changes or mutations in the Duchenne Muscular Dystrophy (DMD) gene. This gene is part of the hereditary material, the DNA. These muscle diseases occur almost exclusively in boys. The dystrophin gene is responsible for the production of multiple dystrophin isoforms that occur in different body tissues, namely in the muscles, kidneys, eye and brain. Scientific research in recent years has focused on investigating the link between the disrupted production of dystrophin in the brain and the more frequent occurrence of neurocognitive (i.e. learning and thinking problems) and behavioural problems. The exact role of dystrophin in cognition and behaviour remains unclear. The aim of this thesis was to further describe the relationship between dystrophin in the brain and the common behavioural and neurocognitive problems. In addition, a literature review was used to identify the psychological measurement instruments used in the scientific literature. Finally, little research has been done on treatments to reduce the consequences of behavioural and neurocognitive problems. This dissertation studied two treatments in boys with DMD, namely a psychological intervention (cognitive working memory training) and a medication-based treatment to improve attention (methylphenidate)

Holistic ICT environments for effective mathematics teaching and learning

To understand the numbers world, each child must face a path that includes propaedeutic phases and only overcoming these phases will allow the child to consolidate processes before tackling new ones. If this does not happen, the child becomes self-convinced of \u201dnot being able to understand math\u201d and becomes increasingly aware of it throughout primary school. The transition to middle school may have a significant impact on a child, with specific difficulties or disabilities in learning mathematics, especially if his/her difficulties have not yet been identified. The present thesis studies the contributions of Information and Communication Technology (ICT) in supporting various aspects of mathematical teaching and learning. A multidimensional approach was used. In the first part, empirical studies assessed the effectiveness of digital tools to identify individual differences based on cognitive profiles and emotional responses associated with math performance in children from Northern Italy. In the second part a meta-analysis and systematic review analysis were carried out to evaluate the effectiveness of interventions supporting math learning by means of ICT in the school and home environments respectively. Altogether the thesis indicates that designing holistic ICT environments proves successful for effective mathematics teaching and learning not only for typically developing children but also for students in disadvantaged situations, including those suffering from dyscalculia

EL LABORATORIO DE CIENCIAS DE LA FUTURA ESCUELA. TECNOLOGÍAS Y CONTENIDOS EMERGENTES

Este artigo investiga as tendências atuais na transformação de laboratórios STEM na era da digitalização devido à integração de tecnologias digitais e ao reconhecimento da importância do desenvolvimento de habilidades metacognitivas. O artigo examina o papel da metacognição e seu impacto no processo de aprendizagem, bem como o uso de tecnologias digitais, como laboratórios remotos, laboratórios virtuais, realidade aumentada, realidade virtual e dispositivos móveis na educação STEM. Os resultados desta pesquisa sugerem que o uso dessas tecnologias digitais pode ser benéfico para a aprendizagem de ciências no ensino superior e secundário. Além disso, essas tecnologias podem ser usadas para promover o engajamento, a colaboração e o acesso dos alunos ao conhecimento científico. Além disso, a metacognição é uma habilidade importante para professores e alunos, e pode ser desenvolvida através do uso da pirâmide do conhecimento, pirâmide de inteligência emocional, pirâmide metacognitiva e modelos de pirâmide de superdotação.This paper investigates the current trends in the transformation of STEM laboratories in the age of digitization due to the integration of digital technologies and the recognition of the importance of developing metacognitive skills. The paper examines the role of metacognition and its impact on the learning process, as well as the use of digital technologies such as remote labs, virtual labs, augmented reality, virtual reality, and mobile devices in STEM education. Results from this research suggest that the use of these digital technologies can be beneficial for science learning in both higher and secondary education. Additionally, these technologies can be used to promote student engagement, collaboration, and access to scientific knowledge. Furthermore, metacognition is an important skill for both teachers and students, and can be developed through the use of the knowledge pyramid, emotional intelligence pyramid, metacognitive pyramid, and giftedness pyramid models.Este artículo investiga las tendencias actuales en la transformación de los laboratorios STEM en la era de la digitalización debido a la integración de tecnologías digitales y al reconocimiento de la importancia del desarrollo de habilidades metacognitivas. El documento examina el papel de la metacognición y su impacto en el proceso de aprendizaje, así como el uso de tecnologías digitales como laboratorios remotos, laboratorios virtuales, realidad aumentada, realidad virtual y dispositivos móviles en la educación STEM. Los resultados de esta investigación sugieren que el uso de estas tecnologías digitales puede ser beneficioso para el aprendizaje de las ciencias tanto en la educación superior como en la secundaria. Además, estas tecnologías pueden utilizarse para promover la participación, colaboración y acceso al conocimiento científico por parte de los estudiantes. Además, la metacognición es una habilidad importante tanto para profesores como para estudiantes y puede desarrollarse mediante el uso de los modelos de pirámide del conocimiento, pirámide de inteligencia emocional, pirámide metacognitiva y pirámide de talento.Este artigo investiga as tendências atuais na transformação de laboratórios STEM na era da digitalização devido à integração de tecnologias digitais e ao reconhecimento da importância do desenvolvimento de habilidades metacognitivas. O artigo examina o papel da metacognição e seu impacto no processo de aprendizagem, bem como o uso de tecnologias digitais, como laboratórios remotos, laboratórios virtuais, realidade aumentada, realidade virtual e dispositivos móveis na educação STEM. Os resultados desta pesquisa sugerem que o uso dessas tecnologias digitais pode ser benéfico para a aprendizagem de ciências no ensino superior e secundário. Além disso, essas tecnologias podem ser usadas para promover o engajamento, a colaboração e o acesso dos alunos ao conhecimento científico. Além disso, a metacognição é uma habilidade importante para professores e alunos, e pode ser desenvolvida através do uso da pirâmide do conhecimento, pirâmide de inteligência emocional, pirâmide metacognitiva e modelos de pirâmide de superdotação

Annual Report 2014

This document is a compendium of the research activity carried out by the IR3C during the year 2014, and describes its eleven Research Groups of Excellence, the two lines of research, the publications, funded projects, patents, and other activities within this period