152,858 research outputs found
Fully automated segmentation and tracking of the intima media thickness in ultrasound video sequences of the common carotid artery
AbstractâThe robust identification and measurement of the intima media thickness (IMT) has a high clinical relevance because it represents one of the most precise predictors used in the assessment of potential future cardiovascular events. To facilitate the analysis of arterial wall thickening in serial clinical investigations, in this paper we have developed a novel fully automatic algorithm for the segmentation, measurement, and tracking of the intima media complex (IMC) in B-mode ultrasound video sequences. The proposed algorithm entails a two-stage image analysis process that initially addresses the segmentation of the IMC in the first frame of the ultrasound video sequence using a model-based approach; in the second step, a novel customized tracking procedure is applied to robustly detect the IMC in the subsequent frames. For the video tracking procedure, we introduce a spatially coherent algorithm called adaptive normalized correlation that prevents the tracking process from converging to wrong arterial interfaces. This represents the main contribution of this paper and was developed to deal with inconsistencies in the appearance of the IMC over the cardiac cycle. The quantitative evaluation has been carried out on 40 ultrasound video sequences of the common carotid artery (CCA) by comparing the results returned by the developed algorithm with respect to ground truth data that has been manually annotated by clinical experts. The measured IMTmean ± standard deviation recorded by the proposed algorithm is 0.60 mm ± 0.10, with a mean coefficient of variation (CV) of 2.05%, whereas the corresponding result obtained for the manually annotated ground truth data is 0.60 mm ± 0.11 with a mean CV equal to 5.60%. The numerical results reported in this paper indicate that the proposed algorithm is able to correctly segment and track the IMC in ultrasound CCA video sequences, and we were encouraged by the stability of our technique when applied to data captured under different imaging conditions. Future clinical studies will focus on the evaluation of patients that are affected by advanced cardiovascular conditions such as focal thickening and arterial plaques
Recommended from our members
Accomplishments and challenges in stem cell imaging in vivo.
Stem cell therapies have demonstrated promising preclinical results, but very few applications have reached the clinic owing to safety and efficacy concerns. Translation would benefit greatly if stem cell survival, distribution and function could be assessed in vivo post-transplantation, particularly in patients. Advances in molecular imaging have led to extraordinary progress, with several strategies being deployed to understand the fate of stem cells in vivo using magnetic resonance, scintigraphy, PET, ultrasound and optical imaging. Here, we review the recent advances, challenges and future perspectives and opportunities in stem cell tracking and functional assessment, as well as the advantages and challenges of each imaging approach
Particle detection and tracking in fluorescence time-lapse imaging: a contrario approach
This paper proposes a probabilistic approach for the detection and the
tracking of particles in fluorescent time-lapse imaging. In the presence of a
very noised and poor-quality data, particles and trajectories can be
characterized by an a contrario model, that estimates the probability of
observing the structures of interest in random data. This approach, first
introduced in the modeling of human visual perception and then successfully
applied in many image processing tasks, leads to algorithms that neither
require a previous learning stage, nor a tedious parameter tuning and are very
robust to noise. Comparative evaluations against a well-established baseline
show that the proposed approach outperforms the state of the art.Comment: Published in Journal of Machine Vision and Application
A perceptual comparison of empirical and predictive region-of-interest video
When viewing multimedia presentations, a user only
attends to a relatively small part of the video display at any one point in time. By shifting allocation of bandwidth from peripheral areas to those locations where a userâs gaze is more likely to rest, attentive displays can be produced. Attentive displays aim to reduce resource requirements while minimizing negative user perceptionâunderstood in this paper as not only a userâs ability to assimilate and understand information but also his/her subjective satisfaction with the video content. This paper introduces and discusses a perceptual comparison between two region-of-interest display (RoID) adaptation techniques. A RoID is an attentive display where bandwidth has been preallocated around measured or highly probable areas of user gaze. In this paper, video content was manipulated using two sources of data: empirical measured data (captured using eye-tracking technology) and predictive data (calculated from the physical characteristics of the video data). Results show that display adaptation causes significant variation in usersâ understanding of specific multimedia content. Interestingly, RoID adaptation and the type of video being presented both affect user perception of video quality. Moreover, the use of frame rates less than 15 frames per second, for any video adaptation technique, caused a significant reduction in user perceived quality, suggesting that although users are aware of video quality reduction, it does impact level of information assimilation and understanding. Results also highlight that user level of enjoyment is significantly affected by the type of video yet is not as affected by the quality or type of video adaptationâan interesting implication in the field of entertainment
Social media mining for identification and exploration of health-related information from pregnant women
Widespread use of social media has led to the generation of substantial
amounts of information about individuals, including health-related information.
Social media provides the opportunity to study health-related information about
selected population groups who may be of interest for a particular study. In
this paper, we explore the possibility of utilizing social media to perform
targeted data collection and analysis from a particular population group --
pregnant women. We hypothesize that we can use social media to identify cohorts
of pregnant women and follow them over time to analyze crucial health-related
information. To identify potentially pregnant women, we employ simple
rule-based searches that attempt to detect pregnancy announcements with
moderate precision. To further filter out false positives and noise, we employ
a supervised classifier using a small number of hand-annotated data. We then
collect their posts over time to create longitudinal health timelines and
attempt to divide the timelines into different pregnancy trimesters. Finally,
we assess the usefulness of the timelines by performing a preliminary analysis
to estimate drug intake patterns of our cohort at different trimesters. Our
rule-based cohort identification technique collected 53,820 users over thirty
months from Twitter. Our pregnancy announcement classification technique
achieved an F-measure of 0.81 for the pregnancy class, resulting in 34,895 user
timelines. Analysis of the timelines revealed that pertinent health-related
information, such as drug-intake and adverse reactions can be mined from the
data. Our approach to using user timelines in this fashion has produced very
encouraging results and can be employed for other important tasks where
cohorts, for which health-related information may not be available from other
sources, are required to be followed over time to derive population-based
estimates.Comment: 9 page
Privacy Implications of Health Information Seeking on the Web
This article investigates privacy risks to those visiting health- related web
pages. The population of pages analyzed is derived from the 50 top search
results for 1,986 common diseases. This yielded a total population of 80,124
unique pages which were analyzed for the presence of third-party HTTP requests.
91% of pages were found to make requests to third parties. Investigation of
URIs revealed that 70% of HTTP Referer strings contained information exposing
specific conditions, treatments, and diseases. This presents a risk to users in
the form of personal identification and blind discrimination. An examination of
extant government and corporate policies reveals that users are insufficiently
protected from such risks
- âŠ