Fuzzy Logic in Clinical Practice Decision Support Systems

Computerized clinical guidelines can provide significant benefits to health outcomes and costs, however, their effective implementation presents significant problems. Vagueness and ambiguity inherent in natural (textual) clinical guidelines is not readily amenable to formulating automated alerts or advice. Fuzzy logic allows us to formalize the treatment of vagueness in a decision support architecture. This paper discusses sources of fuzziness in clinical practice guidelines. We consider how fuzzy logic can be applied and give a set of heuristics for the clinical guideline knowledge engineer for addressing uncertainty in practice guidelines. We describe the specific applicability of fuzzy logic to the decision support behavior of Care Plan On-Line, an intranet-based chronic care planning system for General Practitioners

A Case-Based Reasoning Model Powered by Deep Learning for Radiology Report Recommendation

Case-Based Reasoning models are one of the most used reasoning paradigms in expert-knowledge-driven areas. One of the most prominent fields of use of these systems is the medical sector, where explainable models are required. However, these models are considerably reliant on user input and the introduction of relevant curated data. Deep learning approaches offer an analogous solution, where user input is not required. This paper proposes a hybrid Case-Based Reasoning, Deep Learning framework for medical-related applications, focusing on the generation of medical reports. The proposal combines the explainability and user-focused approach of case-based reasoning models with the deep learning techniques performance. Moreover, the framework is fully modular to fit a wide variety of tasks and data, such as real-time sensor captured data, images, or text, to name a few. An implementation of the proposed framework focusing on radiology report generation assistance is provided. This implementation is used to evaluate the proposal, showing that it can provide meaningful and accurate corrections, even when the amount of information available is minimal. Additional tests on the optimization degree of the case base are also performed, evidencing how the proposed framework can optimize this base to achieve optimal performance

A Survey of GPT-3 Family Large Language Models Including ChatGPT and GPT-4

Large language models (LLMs) are a special class of pretrained language models obtained by scaling model size, pretraining corpus and computation. LLMs, because of their large size and pretraining on large volumes of text data, exhibit special abilities which allow them to achieve remarkable performances without any task-specific training in many of the natural language processing tasks. The era of LLMs started with OpenAI GPT-3 model, and the popularity of LLMs is increasing exponentially after the introduction of models like ChatGPT and GPT4. We refer to GPT-3 and its successor OpenAI models, including ChatGPT and GPT4, as GPT-3 family large language models (GLLMs). With the ever-rising popularity of GLLMs, especially in the research community, there is a strong need for a comprehensive survey which summarizes the recent research progress in multiple dimensions and can guide the research community with insightful future research directions. We start the survey paper with foundation concepts like transformers, transfer learning, self-supervised learning, pretrained language models and large language models. We then present a brief overview of GLLMs and discuss the performances of GLLMs in various downstream tasks, specific domains and multiple languages. We also discuss the data labelling and data augmentation abilities of GLLMs, the robustness of GLLMs, the effectiveness of GLLMs as evaluators, and finally, conclude with multiple insightful future research directions. To summarize, this comprehensive survey paper will serve as a good resource for both academic and industry people to stay updated with the latest research related to GPT-3 family large language models.Comment: Preprint under review, 58 page