665 research outputs found
A Survey on Wireless Sensor Network Security
Wireless sensor networks (WSNs) have recently attracted a lot of interest in
the research community due their wide range of applications. Due to distributed
nature of these networks and their deployment in remote areas, these networks
are vulnerable to numerous security threats that can adversely affect their
proper functioning. This problem is more critical if the network is deployed
for some mission-critical applications such as in a tactical battlefield.
Random failure of nodes is also very likely in real-life deployment scenarios.
Due to resource constraints in the sensor nodes, traditional security
mechanisms with large overhead of computation and communication are infeasible
in WSNs. Security in sensor networks is, therefore, a particularly challenging
task. This paper discusses the current state of the art in security mechanisms
for WSNs. Various types of attacks are discussed and their countermeasures
presented. A brief discussion on the future direction of research in WSN
security is also included.Comment: 24 pages, 4 figures, 2 table
Architecture and Advanced Electronics Pathways Toward Highly Adaptive Energy- Efficient Computing
With the explosion of the number of compute nodes, the bottleneck of future computing systems lies in the network architecture connecting the nodes. Addressing the bottleneck requires replacing current backplane-based network topologies. We propose to revolutionize computing electronics by realizing embedded optical waveguides for onboard networking and wireless chip-to-chip links at 200-GHz carrier frequency connecting neighboring boards in a rack. The control of novel rate-adaptive optical and mm-wave transceivers needs tight interlinking with the system software for runtime resource management
Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle
Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production. In many types of cancers this leads, even in the presence of oxygen, to the secretion of carbon equivalents (usually in the form of lactate) in the cell's surroundings, a feature known as the Warburg effect. While the molecular basis of this phenomenon are still to be elucidated, it is clear that the spilling of energy resources contributes to creating a peculiar microenvironment for tumors, possibly characterized by a degree of toxicity. This suggests that mechanisms for recycling the fermentation products (e.g. a lactate shuttle) may be active, effectively inducing a mutually beneficial metabolic coupling between aberrant and non-aberrant cells. Here we analyze this scenario through a large-scale in silico metabolic model of interacting human cells. By going beyond the cell-autonomous description, we show that elementary physico-chemical constraints indeed favor the establishment of such a coupling under very broad conditions. The characterization we obtained by tuning the aberrant cell's demand for ATP, amino-acids and fatty acids and/or the imbalance in nutrient partitioning provides quantitative support to the idea that synergistic multi-cell effects play a central role in cancer sustainment
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