22 research outputs found

    DDR5 클락 버퍼를 위한 LC PLL의 설계

    Get PDF
    학위논문(석사) -- 서울대학교대학원 : 공과대학 전기·정보공학부, 2022. 8. 정덕균.This thesis describes a wide-range, fast-locking LC PLL for DDR5 clock buffer application. To operate LC PLL at wide range of input frequency, proposed PLL uses LC VCO with 28GHz center frequency and calculates appropriate division ratio of programmable divider for certain input frequen-cy at transient state. Calculating division ratio is achieved by using integer counter and fractional counter, detecting frequency of input clock at transient state. After calculating division ratio, proposed PLL operates as 3rd order charge pump PLL with optimum current value to lock fast. Proposed PLL is described with Systemverilog and simulation results shows that proposed LC PLL operates at 1 ~ 4.2GHz input frequency, while successfully acquires to lock at under 1μs. Also, LC-VCO is designed in a 40nm CMOS and simulation results shows that tuning range of VCO is ±9.25% with respect to center frequency of 28.2GHz, and VCO dissipates 26.4mW and phase noise is –104.86dBc/Hz at 1MHz offset, operating at center fre-quency with 1.1V supply voltage.본 논문은 DDR5 Clock Buffer를 위한, 넓은 범위에서 빠르게 락을 하는 LC PLL에 대해서 설명한다. 넓은 범위의 입력 주파수에서 LC PLL을 동작하기 위해, 제안한 PLL은 28GHz가 중심 주파수인 LC VCO을 사용하여, 과도 상태에서 특정 입력 주파수에 알맞는 프로그램 가능한divider의 제수를 계산한다. 제수의 계산은 과도 상태에서 입력 클락의 주파수를 감지하는 정수 카운터와 소수 카운터를 통해 이루어진다. 제수의 계산 이후, 제안한 PLL은 빠르게 락을 하기 위한 최적의 전류 값으로 3차의 Charge pump PLL로 동작한다. 제안한 PLL은 systemverilog로 기술되었고 시뮬레이션 결과 제안한 LC PLL은 1 ~ 4.2GHz의 입력주파수에서 동작하며, 1us 이내에서 성공적으로 락을 한다. 또한, LC-VCO가 40nm CMOS 공정에서 설계되었고, 시뮬레이션 결과 VCO의 튜닝 범위가 중심 주파수 28.2GHz을 기준으로 ±9.25%이고, 중심 주파수와 1.1V 공급 전압에서 26.4mW의 전력을 소모하고, phase noise가 1MHz 오프셋에서 -104.86dBc/Hz임을 확인할 수 있었다.CHAPTER 1 INTRODUCTION 1 1.1 MOTIVATION 1 1.2 THESIS ORGANIZATION 3 CHAPTER 2 BACKGROUND ON LC PLL 4 2.1 BASIS OF PLL 4 2.2 FREQUENCY RANGE AND LOCK TIME OF PLL 11 2.2.1 FREQUENCY RANGE 11 2.2.2 LOCK TIME 13 2.3 BASIS OF LC VCO 15 CHAPTER 3 DESIGN OF LC PLL FOR DDR5 CLOCK BUFFER 18 3.1 DESIGN CONSIDERATION 18 3.2 OVERALL ARCHITECTURE 20 3.3 OPERATION PRINCIPLE 24 3.4 IMPLEMENTATION OF LC VCO 33 3.5 ALTERNATIVE DESIGN CHOICE OF LC PLL FOR DDR5 CLOCK BUFFER 35 CHAPTER 4 SIMULATION RESULT 37 4.1 PLL 37 4.2 LC VCO 42 CHAPTER 5 CONCLUSION 46 BIBLIOGRAPHY 47 초 록 49석

    Digital enhancement techniques for fractional-N frequency synthesizers

    Get PDF
    Meeting the demand for unprecedented connectivity in the era of internet-of-things (IoT) requires extremely energy efficient operation of IoT nodes to extend battery life. Managing the data traffic generated by trillions of such nodes also puts severe energy constraints on the data centers. Clock generators that are essential elements in these systems consume significant power and therefore must be optimized for low power and high performance. The focus of this thesis is on improving the energy efficiency of frequency synthesizers and clocking modules by exploring design techniques at both the architectural and circuit levels. In the first part of this work, a digital fractional-N phase locked loop (FNPLL) that employs a high resolution time-to-digital converter (TDC) and a truly ΔΣ fractional divider to achieve low in-band noise with a wide bandwidth is presented. The fractional divider employs a digital-to-time converter (DTC) to cancel out ΔΣ quantization noise in time domain, thus alleviating TDC dynamic range requirements. The proposed digital architecture adopts a narrow range low-power time-amplifier based TDC (TA-TDC) to achieve sub 1ps resolution. Fabricated in 65nm CMOS process, the prototype PLL achieves better than -106dBc/Hz in-band noise and 3MHz PLL bandwidth at 4.5GHz output frequency using 50MHz reference. The PLL achieves excellent jitter performance of 490fsrms, while consumes only 3.7mW. This translates to the best reported jitter-power figure-of-merit (FoM) of -240.5dB among previously reported FNPLLs. Phase noise performance of ring oscillator based digital FNPLLs is severely compromised by conflicting bandwidth requirements to simultaneously suppress oscillator phase and quantization noise introduced by the TDC, ΔΣ fractional divider, and digital-to-analog converter (DAC). As a consequence, their FoM that quantifies the power-jitter tradeoff is at least 25dB worse than their LC-oscillator based FNPLL counterparts. In the second part of this thesis, we seek to close this performance gap by extending PLL bandwidth using quantization noise cancellation techniques and by employing a dual-path digital loop filter to suppress the detrimental impact of DAC quantization noise. A prototype was implemented in a 65nm CMOS process operating over a wide frequency range of 2.0GHz-5.5GHz using a modified extended range multi-modulus divider with seamless switching. The proposed digital FNPLL achieves 1.9psrms integrated jitter while consuming only 4mW at 5GHz output. The measured in-band phase noise is better than -96 dBc/Hz at 1MHz offset. The proposed FNPLL achieves wide bandwidth up to 6MHz using a 50 MHz reference and its FoM is -228.5dB, which is at about 20dB better than previously reported ring-based digital FNPLLs. In the third part, we propose a new multi-output clock generator architecture using open loop fractional dividers for system-on-chip (SoC) platforms. Modern multi-core processors use per core clocking, where each core runs at its own speed. The core frequency can be changed dynamically to optimize for performance or power dissipation using a dynamic frequency scaling (DFS) technique. Fast frequency switching is highly desirable as long as it does not interrupt code execution; therefore it requires smooth frequency transitions with no undershoots. The second main requirement in processor clocking is the capability of spread spectrum frequency modulation. By spreading the clock energy across a wide bandwidth, the electromagnetic interference (EMI) is dramatically reduced. A conventional PLL clock generation approach suffers from a slow frequency settling and limited spread spectrum modulation capabilities. The proposed open loop fractional divider architecture overcomes the bandwidth limitation in fractional-N PLLs. The fractional divider switches the output frequency instantaneously and provides an excellent spread spectrum performance, where precise and programmable modulation depth and frequency can be applied to satisfy different EMI requirements. The fractional divider has unlimited modulation bandwidth resulting in spread spectrum modulation with no filtering, unlike fractional-N PLL; consequently it achieves higher EMI reduction. A prototype fractional divider was implemented in a 65nm CMOS process, where the measured peak-to-peak jitter is less than 27ps over a wide frequency range from 20MHz to 1GHz. The total power consumption is about 3.2mW for 1GHz output frequency. The all-digital implementation of the divider occupies the smallest area of 0.017mm2 compared to state-of-the-art designs. As the data rate of serial links goes higher, the jitter requirements of the clock generator become more stringent. Improving the jitter performance of conventional PLLs to less than (200fsrms) always comes with a large power penalty (tens of mWs). This is due to the PLL coupled noise bandwidth trade-off, which imposes stringent noise requirements on the oscillator and/or loop components. Alternatively, an injection-locked clock multiplier (ILCM) provides many advantages in terms of phase noise, power, and area compared to classical PLLs, but they suffer from a narrow lock-in range and a high sensitivity to PVT variations especially at a large multiplication factor (N). In the fourth part of this thesis, a low-jitter, low-power LC-based ILCM with a digital frequency-tracking loop (FTL) is presented. The proposed FTL relies on a new pulse gating technique to continuously tune the oscillator's free-running frequency. The FTL ensures robust operation across PVT variations and resolves the race condition existing in injection locked PLLs by decoupling frequency tuning from the injection path. As a result, the phase locking condition is only determined by the injection path. This work also introduces an accurate theoretical large-signal analysis for phase domain response (PDR) of injection locked oscillators (ILOs). The proposed PDR analysis captures the asymmetric nature of ILO's lock-in range, and the impact of frequency error on injection strength and phase noise performance. The proposed architecture and analysis are demonstrated by a prototype fabricated in 65 nm CMOS process with active area of 0.25mm2. The prototype ILCM multiplies the reference frequency by 64 to generate an output clock in the range of 6.75GHz-8.25GHz. A superior jitter performance of 190fsrms is achieved, while consuming only 2.25mW power. This translates to a best FoM of -251dB. Unlike conventional PLLs, ILCMs have been fundamentally limited to only integer-N operation and cannot synthesize fractional-N frequencies. In the last part of this thesis, we extend the merits of ILCMs to fractional-N and overcome this fundamental limitation. We employ DTC-based QNC techniques in order to align injected pulses to the oscillator's zero crossings, which enables it to pull the oscillator toward phase lock, thus realizing a fractional-N ILCM. Fabricated in 65nm CMOS process, a prototype 20-bit fractional-N ILCM with an output range of 6.75GHz-8.25GHz consumes only 3.25mW. It achieves excellent jitter performance of 110fsrms and 175fsrms in integer- and fractional-N modes respectively, which translates to the best-reported FoM in both integer- (-255dB) and fractional-N (-252dB) modes. The proposed fractional-N ILCM also features the first-reported rapid on/off capability, where the transient absolute jitter performance at wake-up is bounded below 4ps after less than 4ns. This demonstrates almost instantaneous phase settling. This unique capability enables tremendous energy saving by turning on the clock multiplier only when needed. This energy proportional operation leverages idle times to save power at the system-level of wireline and wireless transceivers

    Self-Calibrated, Low-Jitter and Low-Reference-Spur Injection-Locked Clock Multipliers

    Get PDF
    Department of Electrical EngineeringThis dissertation focuses primarily on the design of calibrators for the injection-locked clock multiplier (ILCM). ILCMs have advantage to achieve an excellent jitter performance at low cost, in terms of area and power consumption. The wide loop bandwidth (BW) of the injection technique could reject the noise of voltage-controlled oscillator (VCO), making it thus suitable for the rejection of poor noise of a ring-VCO and a high frequency LC-VCO. However, it is difficult to use without calibrators because of its sensitiveness in process-voltage-temperature (PVT) variations. In Chapter 2, conventional frequency calibrators are introduced and discussed. This dissertation introduces two types of calibrators for low-power high-frequency LC-VCO-based ILFMs in Chapter 3 and Chapter 4 and high-performance ring-VCO-based ILCM in Chapter 5. First, Chapter 3 presents a low power and compact area LC-tank-based frequency multiplier. In the proposed architecture, the input signals have a pulsed waveform that involves many high-order harmonics. Using an LC-tank that amplifies only the target harmonic component, while suppressing others, the output signal at the target frequency can be obtained. Since the core current flows for a very short duration, due to the pulsed input signals, the average power consumption can be dramatically reduced. Effective removal of spurious tones due to the damping of the signal is achieved using a limiting amplifier. In this work, a prototype frequency tripler using the proposed architecture was designed in a 65 nm CMOS process. The power consumption was 950 ??W, and the active area was 0.08 mm2. At a 3.12 GHz frequency, the phase noise degradation with respect to the theoretical bound was less than 0.5 dB. Second, Chapter 4 presents an ultra-low-phase-noise ILFM for millimeter wave (mm-wave) fifth-generation (5G) transceivers. Using an ultra-low-power frequency-tracking loop (FTL), the proposed ILFM is able to correct the frequency drifts of the quadrature voltage-controlled oscillator of the ILFM in a real-time fashion. Since the FTL is monitoring the averages of phase deviations rather than detecting or sampling the instantaneous values, it requires only 600??W to continue to calibrate the ILFM that generates an mm-wave signal with an output frequency from 27 to 30 GHz. The proposed ILFM was fabricated in a 65-nm CMOS process. The 10-MHz phase noise of the 29.25-GHz output signal was ???129.7 dBc/Hz, and its variations across temperatures and supply voltages were less than 2 dB. The integrated phase noise from 1 kHz to 100 MHz and the rms jitter were???39.1 dBc and 86 fs, respectively. Third, Chapter 5 presents a low-jitter, low-reference-spur ring voltage-controlled oscillator (ring VCO)-based ILCM. Since the proposed triple-point frequency/phase/slope calibrator (TP-FPSC) can accurately remove the three root causes of the frequency errors of ILCMs (i.e., frequency drift, phase offset, and slope modulation), the ILCM of this work is able to achieve a low-level reference spur. In addition, the calibrating loop for the frequency drift of the TP-FPSC offers an additional suppression to the in-band phase noise of the output signal. This capability of the TP-FPSC and the naturally wide bandwidth of the injection-locking mechanism allows the ILCM to achieve a very low RMS jitter. The ILCM was fabricated in a 65-nm CMOS technology. The measured reference spur and RMS jitter were ???72 dBc and 140 fs, respectively, both of which are the best among the state-of-the-art ILCMs. The active silicon area was 0.055 mm2, and the power consumption was 11.0 mW.clos

    The Efficient Design of Time-to-Digital Converters

    Get PDF

    가변기능형 아날로그 블록 기반의 현장 프로그램이 가능한 혼성 신호 집적회로의 설계

    Get PDF
    학위논문 (박사)-- 서울대학교 대학원 공과대학 전기·컴퓨터공학부, 2017. 8. 김재하.Fast-emerging electronic device applications demand a variety of new mixed-signal ICs to be developed in fast cycle and with low cost. While field-programmable gate arrays (FPGAs) are established solutions for timely and low-cost prototyping of digital systems, their counterpart for mixed-signal circuits is still an active area for research. This thesis presents a design of a field-programmable IC for analog/mixed-signal circuits, which solves many challenges with the previous works by performing analog functions in time domain. In order to realize the field-programmable analog functionality, time-domain configurable analog block (TCAB) is proposed. A single TCAB can be programmed to various analog circuits, including a time-to-digital converter, digitally-controlled oscillator, digitally-controlled delay cell, digital pulse-width modulator, and phase interpolator. In addition, the TCABs convey and process analog information using the frequency, pulse width, delay, or phase of digital pulses or pulse sequences, rather than using analog voltage or current signals for less susceptibility to attenuation and noise. This analog information expressed in the digital pulses makes it easy to implement scalable programmable interconnects among the TCABs. The architecture of field-programmable IC capable of emulating todays diverse mixed-signal systems is also introduced. In addition to the TCABs, the proposed IC also includes arrays of configurable logic blocks (CLBs) and programmable arithmetic logic units (ALUs) for programmable digital functions. By programming the functionality of the TCAB, CLB, and ALU arrays and configuring the interconnects, the chip can implement various mixed-signal systems. A prototype IC fabricated with 65-nm CMOS technology demonstrates the versatile programmability of the proposed TCAB and the IC by being successfully operated as a 1-GHz phase-locked loop with a 12.3-psrms integrated jitter, as a 50-MS/s analog-to-digital converter with a 32.5-dB SNDR, and as a 1.2-to-0.7V DC–DC converter with 95.5 % efficiency.CHAPTER 1 INTRODUCTION 1 1.1 MOTIVATIONS 1 1.2 THESIS CONTRIBUTION AND ORGANIZATION 5 CHAPTER 2 TIME-DOMAIN CONFIGURABLE ANALOG BLOCK 7 2.1 OVERVIEW OF THE TCAB 9 2.1.1. RECONFIGURABLE FUNCTIONALITY 9 2.1.2. TIME-DOMAIN SIGNAL PROCESSING 14 2.2 CIRCUIT IMPLEMENTATION OF THE TCAB 17 2.3 VERSATILE PROGRAMMABILITY OF TCAB 24 2.3.1. RELAXATION OSCILLATOR 24 2.3.2. DIGITALLY-CONTROLLED OSCILLATOR 28 2.3.3. DIGITAL PULSE-WIDTH MODULATOR 32 2.3.4. GATED OSCILLATOR 34 2.3.5. DIGITALLY-CONTROLLED DELAY CELL 35 2.3.6. PHASE INTERPOLATOR 37 2.3.7. MULTIPHASE DCO 39 2.3.8. NON-OVERLAPPING PULSE GENERATOR 41 2.4 TCAB ARRAY WITH PROGRAMMABLE INTERCONNECTS 43 2.4.1. TCAB ARRAY COMPOSITION 43 2.4.2. PROGRAMMABLE INTERCONNECTS 44 CHAPTER 3 PROPOSED ARCHITECTURE FOR FIELD-PROGRAMMABLE MIXED-SIGNAL IC 49 CHAPTER 4 CIRCUIT IMPLEMENTATION 54 4.1 CONFIGURABLE LOGIC BLOCK ARRAY 55 4.1.1. CONFIGURABLE LOGIC BLOCK 55 4.1.2. CLB ARRAY 56 4.2 ARITHMETIC LOGIC UNIT ARRAY 58 4.2.1. ARITHMETIC LOGIC UNIT 58 4.2.2. ALU ARRAY 61 4.3 INTERFACING BLOCKS 63 4.3.1. VOLTAGE-TO-TIME CONVERTER 64 4.3.2. PHASE-FREQUENCY DETECTOR 65 4.3.3. COUNTER BLOCK 66 4.3.4. TIME-TO-VOLTAGE CONVERTER 68 4.4 PROGRAM METHOD 70 CHAPTER 5 MIXED-SIGNAL EXAMPLES AND EXPERIMENTAL RESULTS 73 5.1 MEASUREMENT RESULTS OF TCAB 76 5.1.1. DIGITAL PULSE-WIDTH MODULATOR 76 5.1.2. DIGITALLY-CONTROLLED OSCILLATOR 79 5.1.3. GATED OSCILLATOR 81 5.2 DIGITAL PHASE-LOCKED LOOP 83 5.3 ANALOG-TO-DIGITAL CONVERTER 89 5.4 DCDC CONVERTER 94 CHAPTER 6 CONCLUSION 99 BIBLIOGRAPHY 101 초 록 108Docto

    Generation of Frequency Tunable and Low Phase Noise Micro- and Millimeter-Wave Signals using Photonic Technologies

    Get PDF
    The concept of generating micro- and millimeter-wave signals by optical means offers a variety of unique features compared to purely electronics such as high frequency tunability, ultra-wideband operation and the possibility to distribute micro- and millimeter-wave signals over kilometers of optical fiber to a remote site. These features make the photonic synthesizer concept a very interesting alternative for several applications in the micro- and millimeter-wave regime. This thesis focuses on the realization and characterization of different photonic synthesizer concepts for the optical generation of frequency tunable and low phase noise micro- and millimeter-wave signals. Advanced microwave photonic approaches utilizing external optical modulation and optical multiplication will be presented, offering high frequency optical millimeter-wave generation up to 110 GHz with superior performances in terms of maximum frequency tuning ranges and phase noise characteristics. In addition, the concept of a novel dual-loop optoelectronic oscillator will be presented that enables optical millimeter-wave signal generation without the need of any electronic reference oscillator. By using the developed dual-loop optoelectronic oscillator, microwave signal generation with tuning ranges in the gigahertz regime has been experimentally demonstrated for the first time.Das Konzept der optischen Mikro- und Millimeterwellen-Generation bietet gegenüber rein elektronischen Konzepten eine Vielzahl einzigartiger Möglichkeiten, bedingt durch die hohe Frequenzabstimmbarkeit, die extrem hohe Bandbreite sowie die Möglichkeit, Mikro- und Millimeterwellen-Signale über optische Fasern kilometerweit zu einer entfernten Station zu übertragen. Diese Eigenschaften machen das Konzept des photonischen Synthesizers zu einer sehr interessanten Alternative für viele Applikationen im Mikro- und Millimeterwellen-Bereich. Diese Arbeit beschäftigt sich mit der Realisierung und Charakterisierung verschiedener photonischer Synthesizer-Konzepte zur optischen Generation von frequenzabstimmbaren Mikro- und Millimeterwellen-Signalen mit geringem Phasenrauschen. Fortschrittliche photonische Konzepte unter Ausnutzung externer optischer Modulation sowie optischer Multiplikation werden vorgestellt. Diese Konzepte ermöglichen die optische Generierung hochfrequenter Millimeterwellen bis zu 110 GHz mit ausgezeichneter Performance in Bezug auf maximale Frequenzabstimmbarkeit sowie Phasenrauschen. Des Weiteren wurde ein neuartiges Konzept des optoelektronischen Oszillators, bestehend aus zwei Faserringen, vorgestellt, welches die Generierung von Millimeterwellen-Signalen ohne die Notwendigkeit eines elektronischen Referenzoszillators ermöglicht. Mit Hilfe des entwickelten optoelektronischen Oszillators wurde erstmals ein Mikrowellen-Signal mit einer Frequenzabstimmbarkeit im Gigahertz-Bereich experimentell erreicht

    A portable device for time-resolved fluorescence based on an array of CMOS SPADs with integrated microfluidics

    Get PDF
    [eng] Traditionally, molecular analysis is performed in laboratories equipped with desktop instruments operated by specialized technicians. This paradigm has been changing in recent decades, as biosensor technology has become as accurate as desktop instruments, providing results in much shorter periods and miniaturizing the instrumentation, moving the diagnostic tests gradually out of the central laboratory. However, despite the inherent advantages of time-resolved fluorescence spectroscopy applied to molecular diagnosis, it is only in the last decade that POC (Point Of Care) devices have begun to be developed based on the detection of fluorescence, due to the challenge of developing high-performance, portable and low-cost spectroscopic sensors. This thesis presents the development of a compact, robust and low-cost system for molecular diagnosis based on time-resolved fluorescence spectroscopy, which serves as a general-purpose platform for the optical detection of a variety of biomarkers, bridging the gap between the laboratory and the POC of the fluorescence lifetime based bioassays. In particular, two systems with different levels of integration have been developed that combine a one-dimensional array of SPAD (Single-Photon Avalanch Diode) pixels capable of detecting a single photon, with an interchangeable microfluidic cartridge used to insert the sample and a laser diode Pulsed low-cost UV as a source of excitation. The contact-oriented design of the binomial formed by the sensor and the microfluidic, together with the timed operation of the sensors, makes it possible to dispense with the use of lenses and filters. In turn, custom packaging of the sensor chip allows the microfluidic cartridge to be positioned directly on the sensor array without any alignment procedure. Both systems have been validated, determining the decomposition time of quantum dots in 20 nl of solution for different concentrations, emulating a molecular test in a POC device.[cat] Tradicionalment, l'anàlisi molecular es realitza en laboratoris equipats amb instruments de sobretaula operats per tècnics especialitzats. Aquest paradigma ha anat canviant en les últimes dècades, a mesura que la tecnologia de biosensor s'ha tornat tan precisa com els instruments de sobretaula, proporcionant resultats en períodes molt més curts de temps i miniaturitzant la instrumentació, permetent així, traslladar gradualment les proves de diagnòstic fora de laboratori central. No obstant això i malgrat els avantatges inherents de l'espectroscòpia de fluorescència resolta en el temps aplicada a la diagnosi molecular, no ha estat fins a l'última dècada que s'han començat a desenvolupar dispositius POC (Point Of Care) basats en la detecció de la fluorescència, degut al desafiament que suposa el desenvolupament de sensors espectroscòpics d'alt rendiment, portàtils i de baix cost. Aquesta tesi presenta el desenvolupament d'un sistema compacte, robust i de baix cost per al diagnòstic molecular basat en l'espectroscòpia de fluorescència resolta en el temps, que serveixi com a plataforma d'ús general per a la detecció òptica d'una varietat de biomarcadors, tancant la bretxa entre el laboratori i el POC dels bioassaigs basats en l'anàlisi de la pèrdua de la fluorescència. En particular, s'han desenvolupat dos sistemes amb diferents nivells d'integració que combinen una matriu unidimensional de píxels SPAD (Single-Photon Avalanch Diode) capaços de detectar un sol fotó, amb un cartutx microfluídic intercanviable emprat per inserir la mostra, així com un díode làser UV premut de baix cost com a font d'excitació. El disseny orientat a la detecció per contacte de l'binomi format pel sensor i la microfluídica, juntament amb l'operació temporitzada dels sensors, permet prescindir de l'ús de lents i filtres. Al seu torn, l'empaquetat a mida de l'xip sensor permet posicionar el cartutx microfluídic directament sobre la matriu de sensors sense cap procediment d'alineament. Tots dos sistemes han estat validats determinant el temps de descomposició de "quantum dots" en 20 nl de solució per a diferents concentracions, emulant així un assaig molecular en un dispositiu POC
    corecore