Three Puzzles on Mathematics, Computation, and Games

In this lecture I will talk about three mathematical puzzles involving mathematics and computation that have preoccupied me over the years. The first puzzle is to understand the amazing success of the simplex algorithm for linear programming. The second puzzle is about errors made when votes are counted during elections. The third puzzle is: are quantum computers possible?Comment: ICM 2018 plenary lecture, Rio de Janeiro, 36 pages, 7 Figure

Controlling edge dynamics in complex networks

The interaction of distinct units in physical, social, biological and technological systems naturally gives rise to complex network structures. Networks have constantly been in the focus of research for the last decade, with considerable advances in the description of their structural and dynamical properties. However, much less effort has been devoted to studying the controllability of the dynamics taking place on them. Here we introduce and evaluate a dynamical process defined on the edges of a network, and demonstrate that the controllability properties of this process significantly differ from simple nodal dynamics. Evaluation of real-world networks indicates that most of them are more controllable than their randomized counterparts. We also find that transcriptional regulatory networks are particularly easy to control. Analytic calculations show that networks with scale-free degree distributions have better controllability properties than uncorrelated networks, and positively correlated in- and out-degrees enhance the controllability of the proposed dynamics.Comment: Preprint. 24 pages, 4 figures, 2 tables. Source code available at http://github.com/ntamas/netctr

On visions and new approaches Case studies of organisational forms in organic plant breeding and seed production

The report is an exploratory study of the social, financial and legal organisation, and technology applied in five initiatives in the sector of biological seed production and plant breeding in the Netherlands, Germany and Switzerland. The experiences of the studied initiatives are relevant in a period in which interest for organic seed and plant breeding is increasing. A number of the actors in the organic sector consider organic breeding a guarantee the availability of suitable seeds and varieties for the organic sector in terms of agronomic and quality traits. An important requirement is that seeds are produced and developed with technologies that are accepted in the organic sector. In addition, the organic sector is interested in breeding strategies that aim not only at economic, but also at social sustainability

Piezoelectric vibration energy harvesting from airflow in HVAC (Heating Ventilation and Air Conditioning) systems

This study focuses on the design and wind tunnel testing of a high efficiency Energy Harvesting device, based on piezoelectric materials, with possible applications for the sustainability of smart buildings, structures and infrastructures. The development of the device was supported by ESA (the European Space Agency) under a program for the space technology transfer in the period 2014-2016. The EH device harvests the airflow inside Heating, Ventilation and Air Conditioning (HVAC) systems, using a piezoelectric component and an appropriate customizable aerodynamic appendix or fin that takes advantage of specific airflow phenomena (vortex shedding and galloping), and can be implemented for optimizing the energy consumption inside buildings. Focus is given on several relevant aspects of wind tunnel testing: different configurations for the piezoelectric bender (rectangular, cylindrical and T-shaped) are tested and compared, and the effective energy harvesting potential of a working prototype device is assessed

Preliminary Evidence That CD38 Moderates the Association of Neuroticism on Amygdala-Subgenual Cingulate Connectivity.

CD38 genetic variation has been associated with autism spectrum disorders and social anxiety disorder, which may result from CD38's regulation of oxytocin secretion. Converging evidence has found that the rs3796863 A-allele contributes to increased social sensitivity compared to the CC genotype. The current study examined the moderating role of CD38 genetic variants (rs3796863 and rs6449182) that have been associated with enhanced (or reduced) social sensitivity on neural activation related to neuroticism, which is commonly elevated in individuals with social anxiety and depression. Adults (n = 72) with varying levels of social anxiety and depression provided biological samples for DNA extraction, completed a measure of neuroticism, and participated in a standardized emotion processing task (affect matching) while undergoing fMRI. A significant interaction effect was found for rs3796863 x neuroticism that predicted right amygdala-subgenual anterior cingulate cortex (sgACC) functional connectivity. Simple slopes analyses showed a positive association between neuroticism and right amygdala-sgACC connectivity among rs3796863 A-allele carriers. Findings suggest that the more socially sensitive rs3796863 A-allele may partially explain the relationship between a known risk factor (i.e. neuroticism) and promising biomarker (i.e. amygdala-sgACC connectivity) in the development and maintenance of social anxiety and depression