106 research outputs found
Isotropic inverse-problem approach for two-dimensional phase unwrapping
In this paper, we propose a new technique for two-dimensional phase
unwrapping. The unwrapped phase is found as the solution of an inverse problem
that consists in the minimization of an energy functional. The latter includes
a weighted data-fidelity term that favors sparsity in the error between the
true and wrapped phase differences, as well as a regularizer based on
higher-order total-variation. One desirable feature of our method is its
rotation invariance, which allows it to unwrap a much larger class of images
compared to the state of the art. We demonstrate the effectiveness of our
method through several experiments on simulated and real data obtained through
the tomographic phase microscope. The proposed method can enhance the
applicability and outreach of techniques that rely on quantitative phase
evaluation
Image Reconstruction from Undersampled Confocal Microscopy Data using Multiresolution Based Maximum Entropy Regularization
We consider the problem of reconstructing 2D images from randomly
under-sampled confocal microscopy samples. The well known and widely celebrated
total variation regularization, which is the L1 norm of derivatives, turns out
to be unsuitable for this problem; it is unable to handle both noise and
under-sampling together. This issue is linked with the notion of phase
transition phenomenon observed in compressive sensing research, which is
essentially the break-down of total variation methods, when sampling density
gets lower than certain threshold. The severity of this breakdown is determined
by the so-called mutual incoherence between the derivative operators and
measurement operator. In our problem, the mutual incoherence is low, and hence
the total variation regularization gives serious artifacts in the presence of
noise even when the sampling density is not very low. There has been very few
attempts in developing regularization methods that perform better than total
variation regularization for this problem. We develop a multi-resolution based
regularization method that is adaptive to image structure. In our approach, the
desired reconstruction is formulated as a series of coarse-to-fine
multi-resolution reconstructions; for reconstruction at each level, the
regularization is constructed to be adaptive to the image structure, where the
information for adaption is obtained from the reconstruction obtained at
coarser resolution level. This adaptation is achieved by using maximum entropy
principle, where the required adaptive regularization is determined as the
maximizer of entropy subject to the information extracted from the coarse
reconstruction as constraints. We demonstrate the superiority of the proposed
regularization method over existing ones using several reconstruction examples
Efficient Inversion of Multiple-Scattering Model for Optical Diffraction Tomography
Optical diffraction tomography relies on solving an inverse scattering
problem governed by the wave equation. Classical reconstruction algorithms are
based on linear approximations of the forward model (Born or Rytov), which
limits their applicability to thin samples with low refractive-index contrasts.
More recent works have shown the benefit of adopting nonlinear models. They
account for multiple scattering and reflections, improving the quality of
reconstruction. To reduce the complexity and memory requirements of these
methods, we derive an explicit formula for the Jacobian matrix of the nonlinear
Lippmann-Schwinger model which lends itself to an efficient evaluation of the
gradient of the data- fidelity term. This allows us to deploy efficient methods
to solve the corresponding inverse problem subject to sparsity constraints
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