A abordagem POESIA para a integração de dados e serviços na Web semantica

Orientador: Claudia Bauzer MedeirosTese (doutorado) - Universidade Estadual de Campinas, Instituto de ComputaçãoResumo: POESIA (Processes for Open-Ended Systems for lnformation Analysis), a abordagem proposta neste trabalho, visa a construção de processos complexos envolvendo integração e análise de dados de diversas fontes, particularmente em aplicações científicas. A abordagem é centrada em dois tipos de mecanismos da Web semântica: workflows científicos, para especificar e compor serviços Web; e ontologias de domínio, para viabilizar a interoperabilidade e o gerenciamento semânticos dos dados e processos. As principais contribuições desta tese são: (i) um arcabouço teórico para a descrição, localização e composição de dados e serviços na Web, com regras para verificar a consistência semântica de composições desses recursos; (ii) métodos baseados em ontologias de domínio para auxiliar a integração de dados e estimar a proveniência de dados em processos cooperativos na Web; (iii) implementação e validação parcial das propostas, em urna aplicação real no domínio de planejamento agrícola, analisando os benefícios e as limitações de eficiência e escalabilidade da tecnologia atual da Web semântica, face a grandes volumes de dadosAbstract: POESIA (Processes for Open-Ended Systems for Information Analysis), the approach proposed in this work, supports the construction of complex processes that involve the integration and analysis of data from several sources, particularly in scientific applications. This approach is centered in two types of semantic Web mechanisms: scientific workflows, to specify and compose Web services; and domain ontologies, to enable semantic interoperability and management of data and processes. The main contributions of this thesis are: (i) a theoretical framework to describe, discover and compose data and services on the Web, inc1uding mIes to check the semantic consistency of resource compositions; (ii) ontology-based methods to help data integration and estimate data provenance in cooperative processes on the Web; (iii) partial implementation and validation of the proposal, in a real application for the domain of agricultural planning, analyzing the benefits and scalability problems of the current semantic Web technology, when faced with large volumes of dataDoutoradoCiência da ComputaçãoDoutor em Ciência da Computaçã

Self-organizing ontology of biochemically relevant small molecules

<p>Abstract</p> <p>Background</p> <p>The advent of high-throughput experimentation in biochemistry has led to the generation of vast amounts of chemical data, necessitating the development of novel analysis, characterization, and cataloguing techniques and tools. Recently, a movement to publically release such data has advanced biochemical structure-activity relationship research, while providing new challenges, the biggest being the curation, annotation, and classification of this information to facilitate useful biochemical pattern analysis. Unfortunately, the human resources currently employed by the organizations supporting these efforts (e.g. ChEBI) are expanding linearly, while new useful scientific information is being released in a seemingly exponential fashion. Compounding this, currently existing chemical classification and annotation systems are not amenable to automated classification, formal and transparent chemical class definition axiomatization, facile class redefinition, or novel class integration, thus further limiting chemical ontology growth by necessitating human involvement in curation. Clearly, there is a need for the automation of this process, especially for novel chemical entities of biological interest.</p> <p>Results</p> <p>To address this, we present a formal framework based on Semantic Web technologies for the automatic design of chemical ontology which can be used for automated classification of novel entities. We demonstrate the automatic self-assembly of a structure-based chemical ontology based on 60 MeSH and 40 ChEBI chemical classes. This ontology is then used to classify 200 compounds with an accuracy of 92.7%. We extend these structure-based classes with molecular feature information and demonstrate the utility of our framework for classification of functionally relevant chemicals. Finally, we discuss an iterative approach that we envision for future biochemical ontology development.</p> <p>Conclusions</p> <p>We conclude that the proposed methodology can ease the burden of chemical data annotators and dramatically increase their productivity. We anticipate that the use of formal logic in our proposed framework will make chemical classification criteria more transparent to humans and machines alike and will thus facilitate predictive and integrative bioactivity model development.</p

Lost in translation: data integration tools meet the Semantic Web (experiences from the Ondex project)

More information is now being published in machine processable form on the web and, as de-facto distributed knowledge bases are materializing, partly encouraged by the vision of the Semantic Web, the focus is shifting from the publication of this information to its consumption. Platforms for data integration, visualization and analysis that are based on a graph representation of information appear first candidates to be consumers of web-based information that is readily expressible as graphs. The question is whether the adoption of these platforms to information available on the Semantic Web requires some adaptation of their data structures and semantics. Ondex is a network-based data integration, analysis and visualization platform which has been developed in a Life Sciences context. A number of features, including semantic annotation via ontologies and an attention to provenance and evidence, make this an ideal candidate to consume Semantic Web information, as well as a prototype for the application of network analysis tools in this context. By analyzing the Ondex data structure and its usage, we have found a set of discrepancies and errors arising from the semantic mismatch between a procedural approach to network analysis and the implications of a web-based representation of information. We report in the paper on the simple methodology that we have adopted to conduct such analysis, and on issues that we have found which may be relevant for a range of similar platformsComment: Presented at DEIT, Data Engineering and Internet Technology, 2011 IEEE: CFP1113L-CD

Ontology-based patterns for the integration of business processes and enterprise application architectures

Increasingly, enterprises are using Service-Oriented Architecture (SOA) as an approach to Enterprise Application Integration (EAI). SOA has the potential to bridge the gap between business and technology and to improve the reuse of existing applications and the interoperability with new ones. In addition to service architecture descriptions, architecture abstractions like patterns and styles capture design knowledge and allow the reuse of successfully applied designs, thus improving the quality of software. Knowledge gained from integration projects can be captured to build a repository of semantically enriched, experience-based solutions. Business patterns identify the interaction and structure between users, business processes, and data. Specific integration and composition patterns at a more technical level address enterprise application integration and capture reliable architecture solutions. We use an ontology-based approach to capture architecture and process patterns. Ontology techniques for pattern definition, extension and composition are developed and their applicability in business process-driven application integration is demonstrated

Semantic model-driven development of service-centric software architectures

Service-oriented architecture (SOA) is a recent architectural paradigm that has received much attention. The prevalent focus on platforms such as Web services, however, needs to be complemented by appropriate software engineering methods. We propose the model-driven development of service-centric software systems. We present in particular an investigation into the role of enriched semantic modelling for a modeldriven development framework for service-centric software systems. Ontologies as the foundations of semantic modelling and its enhancement through architectural pattern modelling are at the core of the proposed approach. We introduce foundations and discuss the benefits and also the challenges in this context