Application of Semantics to Solve Problems in Life Sciences

Fecha de lectura de Tesis: 10 de diciembre de 2018La cantidad de información que se genera en la Web se ha incrementado en los últimos años. La mayor parte de esta información se encuentra accesible en texto, siendo el ser humano el principal usuario de la Web. Sin embargo, a pesar de todos los avances producidos en el área del procesamiento del lenguaje natural, los ordenadores tienen problemas para procesar esta información textual. En este cotexto, existen dominios de aplicación en los que se están publicando grandes cantidades de información disponible como datos estructurados como en el área de las Ciencias de la Vida. El análisis de estos datos es de vital importancia no sólo para el avance de la ciencia, sino para producir avances en el ámbito de la salud. Sin embargo, estos datos están localizados en diferentes repositorios y almacenados en diferentes formatos que hacen difícil su integración. En este contexto, el paradigma de los Datos Vinculados como una tecnología que incluye la aplicación de algunos estándares propuestos por la comunidad W3C tales como HTTP URIs, los estándares RDF y OWL. Haciendo uso de esta tecnología, se ha desarrollado esta tesis doctoral basada en cubrir los siguientes objetivos principales: 1) promover el uso de los datos vinculados por parte de la comunidad de usuarios del ámbito de las Ciencias de la Vida 2) facilitar el diseño de consultas SPARQL mediante el descubrimiento del modelo subyacente en los repositorios RDF 3) crear un entorno colaborativo que facilite el consumo de Datos Vinculados por usuarios finales, 4) desarrollar un algoritmo que, de forma automática, permita descubrir el modelo semántico en OWL de un repositorio RDF, 5) desarrollar una representación en OWL de ICD-10-CM llamada Dione que ofrezca una metodología automática para la clasificación de enfermedades de pacientes y su posterior validación haciendo uso de un razonador OWL

Semantic Interpretation of User Queries for Question Answering on Interlinked Data

The Web of Data contains a wealth of knowledge belonging to a large number of domains. Retrieving data from such precious interlinked knowledge bases is an issue. By taking the structure of data into account, it is expected that upcoming generation of search engines is approaching to question answering systems, which directly answer user questions. But developing a question answering over these interlinked data sources is still challenging because of two inherent characteristics: First, different datasets employ heterogeneous schemas and each one may only contain a part of the answer for a certain question. Second, constructing a federated formal query across different datasets requires exploiting links between these datasets on both the schema and instance levels. In this respect, several challenges such as resource disambiguation, vocabulary mismatch, inference, link traversal are raised. In this dissertation, we address these challenges in order to build a question answering system for Linked Data. We present our question answering system Sina, which transforms user-supplied queries (i.e. either natural language queries or keyword queries) into conjunctive SPARQL queries over a set of interlinked data sources. The contributions of this work are as follows: 1. A novel approach for determining the most suitable resources for a user-supplied query from different datasets (disambiguation approach). We employed a Hidden Markov Model, whose parameters were bootstrapped with different distribution functions. 2. A novel method for constructing federated formal queries using the disambiguated resources and leveraging the linking structure of the underlying datasets. This approach essentially relies on a combination of domain and range inference as well as a link traversal method for constructing a connected graph, which ultimately renders a corresponding SPARQL query. 3. Regarding the problem of vocabulary mismatch, our contribution is divided into two parts, First, we introduce a number of new query expansion features based on semantic and linguistic inferencing over Linked Data. We evaluate the effectiveness of each feature individually as well as their combinations, employing Support Vector Machines and Decision Trees. Second, we propose a novel method for automatic query expansion, which employs a Hidden Markov Model to obtain the optimal tuples of derived words. 4. We provide two benchmarks for two different tasks to the community of question answering systems. The first one is used for the task of question answering on interlinked datasets (i.e. federated queries over Linked Data). The second one is used for the vocabulary mismatch task. We evaluate the accuracy of our approach using measures like mean reciprocal rank, precision, recall, and F-measure on three interlinked life-science datasets as well as DBpedia. The results of our accuracy evaluation demonstrate the effectiveness of our approach. Moreover, we study the runtime of our approach in its sequential as well as parallel implementations and draw conclusions on the scalability of our approach on Linked Data

Knowledge Organization Systems (KOS) in the Semantic Web: A Multi-Dimensional Review

Since the Simple Knowledge Organization System (SKOS) specification and its SKOS eXtension for Labels (SKOS-XL) became formal W3C recommendations in 2009 a significant number of conventional knowledge organization systems (KOS) (including thesauri, classification schemes, name authorities, and lists of codes and terms, produced before the arrival of the ontology-wave) have made their journeys to join the Semantic Web mainstream. This paper uses "LOD KOS" as an umbrella term to refer to all of the value vocabularies and lightweight ontologies within the Semantic Web framework. The paper provides an overview of what the LOD KOS movement has brought to various communities and users. These are not limited to the colonies of the value vocabulary constructors and providers, nor the catalogers and indexers who have a long history of applying the vocabularies to their products. The LOD dataset producers and LOD service providers, the information architects and interface designers, and researchers in sciences and humanities, are also direct beneficiaries of LOD KOS. The paper examines a set of the collected cases (experimental or in real applications) and aims to find the usages of LOD KOS in order to share the practices and ideas among communities and users. Through the viewpoints of a number of different user groups, the functions of LOD KOS are examined from multiple dimensions. This paper focuses on the LOD dataset producers, vocabulary producers, and researchers (as end-users of KOS).Comment: 31 pages, 12 figures, accepted paper in International Journal on Digital Librarie

Semantic query languages for knowledge-based web services in a construction context

Since the early 2000s, different frameworks were set up to enable web-based collaboration in building projects. Unfortunately, none of these initiatives was granted a long life. Recently, however, the use of web technologies in the building industry has been gaining momentum again, considered some promising technologies for reaching a more interoperable BIM practice. Specifically, this relates to (1) Linked Data and Semantic Web technologies, and (2) cloud-based applications. In order to combine these into a network of interlinked applications and datastores, an agreed-upon mechanism for automatic communication and data retrieval needs to be used. Apart from the W3C standard SPARQL, often considered too high a threshold for developers to implement, there are some recent GraphQL-based solutions that simplify the querying process and its implementation into web services. In this paper, we review two recent open source technologies based on GraphQL, that enable to query Linked Data on the web: GraphQL-LD and HyperGraphQL