31,665 research outputs found

    Introduction to Principal Components Analysis

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    Understanding the inverse equivalent width - luminosity relationship (Baldwin Effect), the topic of this meeting, requires extracting information on continuum and emission line parameters from samples of AGN. We wish to discover whether, and how, different subsets of measured parameters may correlate with each other. This general problem is the domain of Principal Components Analysis (PCA). We discuss the purpose, principles, and the interpretation of PCA, using some examples from QSO spectroscopy. The hope is that identification of relationships among subsets of correlated variables may lead to new physical insight.Comment: Invited review to appear in ``Quasars and Cosmology'', A.S.P. Conference Series 1999. eds. G. J. Ferland, J. A. Baldwin, (San Francisco: ASP). 10 pages, 2 figure

    Factor Analysis of Mixed Data (FAMD) and Multiple Linear Regression in R

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    In the previous projects, it has been worked to statistically analysis of the factors to impact the score of the subjects of Mathematics and Portuguese for several groups of the student from secondary school from Portugal. In this project will be interested in finding a model, hypothetically multiple linear regression, to predict the final score, dependent variable G3, of the student according to some features divide into two groups. One group, analyses the features or predictors which impact in the final score more related to the performance of the students, means variables like study time or past failures. The second group analyses the predictors more relate to a family situation or family relationships. The approach to constructing the linear model is using the principal component results from the analyses of the principal component instead of the original features or predictors. The linear model proposal is: score G3 = a + b1*(PC1) + b2*(PC2) + ... + bk*(PCk) bi = Coefficients PCi = principal component, i: 1, 2, 
, k dimensions Due that the variables are numeric and categorical, it will be used the extension method called Factor Analysis of Mixed Data (FAMD) to deal with data quantitative and data qualitative

    Simple data analysis for biologists

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    This document provides a simple introduction to research methods and analysis tools for biologists or environmental scientists, with particular emphasis on fish biology in devleoping countries

    Nanopipettes as Monitoring Probes for the Single Living Cell: State of the Art and Future Directions in Molecular Biology.

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    Examining the behavior of a single cell within its natural environment is valuable for understanding both the biological processes that control the function of cells and how injury or disease lead to pathological change of their function. Single-cell analysis can reveal information regarding the causes of genetic changes, and it can contribute to studies on the molecular basis of cell transformation and proliferation. By contrast, whole tissue biopsies can only yield information on a statistical average of several processes occurring in a population of different cells. Electrowetting within a nanopipette provides a nanobiopsy platform for the extraction of cellular material from single living cells. Additionally, functionalized nanopipette sensing probes can differentiate analytes based on their size, shape or charge density, making the technology uniquely suited to sensing changes in single-cell dynamics. In this review, we highlight the potential of nanopipette technology as a non-destructive analytical tool to monitor single living cells, with particular attention to integration into applications in molecular biology
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