The Dawn of Open Access to Phylogenetic Data

The scientific enterprise depends critically on the preservation of and open access to published data. This basic tenet applies acutely to phylogenies (estimates of evolutionary relationships among species). Increasingly, phylogenies are estimated from increasingly large, genome-scale datasets using increasingly complex statistical methods that require increasing levels of expertise and computational investment. Moreover, the resulting phylogenetic data provide an explicit historical perspective that critically informs research in a vast and growing number of scientific disciplines. One such use is the study of changes in rates of lineage diversification (speciation - extinction) through time. As part of a meta-analysis in this area, we sought to collect phylogenetic data (comprising nucleotide sequence alignment and tree files) from 217 studies published in 46 journals over a 13-year period. We document our attempts to procure those data (from online archives and by direct request to corresponding authors), and report results of analyses (using Bayesian logistic regression) to assess the impact of various factors on the success of our efforts. Overall, complete phylogenetic data for ~60% of these studies are effectively lost to science. Our study indicates that phylogenetic data are more likely to be deposited in online archives and/or shared upon request when: (1) the publishing journal has a strong data-sharing policy; (2) the publishing journal has a higher impact factor, and; (3) the data are requested from faculty rather than students. Although the situation appears dire, our analyses suggest that it is far from hopeless: recent initiatives by the scientific community -- including policy changes by journals and funding agencies -- are improving the state of affairs

The relationship between the entrepreneurship and the local environment : evidence from Poland

Purpose: The main goal of the research is to investigate the importance of geographical proximity between regions as an entrepreneurship development factor compared to other determinants of entrepreneurship. Design/Methodology/Approach: Three neighbouring regions in south-eastern Poland demonstrating a different level of economic development were selected for the study. The study was carried out at the local level using the division of the three regions into 61 local administrative units. The taxonomic measure of development based on the Weber median and regression analysis (2SLS estimators) were employed. The analysis cover the 2008-2017 period. Findings: The research revealed the weak impact of inter-regional proximity on the entrepreneurship development in less developed regions. The difference in motives for starting a business (opportunity versus necessity entrepreneurship) was indicated as a probable cause for the weak impact of inter-regional geographical proximity on entrepreneurship development in less developed regions. Practical Implications: The study results can be utilised in subsequent examinations of inter regional convergence across Europe. Originality/Value: The value of the paper is the a "territorial" approach to entrepreneurship process which have not been sufficiently examined so far. The research seeks to contribute to a better understanding of the entrepreneurship process in countries which have relatively recently adopted market rules, eg. Poland.peer-reviewe

Community hospitals – the place of local service provision in a modernising NHS: an integrative thematic literature review

Background: Recent developments within the United Kingdom's (UK) health care system have reawakened interest in community hospitals (CHs) and their role in the provision of health care. This integrative literature review sought to identify and assess the current evidence base for CHs. Methods: A range of electronic reference databases were searched from January 1984 to either December 2004 or February 2005: Medline, Embase, Web of Knowledge, BNI, CINAHL, HMIC, ASSIA, PsychInfo, SIGLE, Dissertation Abstracts, Cochrane Library, Kings Fund website, using both keywords and text words. Thematic analysis identified recurrent themes across the literature; narrative analyses were written for each theme, identifying unifying concepts and discrepant issues. Results: The search strategy identified over 16,000 international references. We included papers of any study design focussing on hospitals in which care was led principally by general practitioners or nurses. Papers from developing countries were excluded. A review of titles revealed 641 potentially relevant references; abstract appraisal identified 161 references for review. During data extraction, a further 48 papers were excluded, leaving 113 papers in the final review. The most common methodological approaches were cross-sectional/descriptive studies, commentaries and expert opinion. There were few experimental studies, systematic reviews, economic studies or studies that reported on longer-term outcomes. The key themes identified were origin and location of CHs; their place in the continuum of care; services provided; effectiveness, efficiency and equity of CHs; and views of patients and staff. In general, there was a lack of robust evidence for the role of CHs, which is partly due to the ad hoc nature of their development and lack of clear strategic vision for their future. Evidence for the effectiveness and efficiency of the services provided was limited. Most people admitted to CHs appeared to be older, suggesting that admittance to CHs was age-related rather than condition-related. Conclusion: Overall the literature surveyed was long on opinion and short of robust studies on CHs. While lack of evidence on CHs does not imply lack of effect, there is an urgent need to develop a research agenda that addresses the key issues of health care delivery in the CH setting

Report on the Information Retrieval Festival (IRFest2017)

The Information Retrieval Festival took place in April 2017 in Glasgow. The focus of the workshop was to bring together IR researchers from the various Scottish universities and beyond in order to facilitate more awareness, increased interaction and reflection on the status of the field and its future. The program included an industry session, research talks, demos and posters as well as two keynotes. The first keynote was delivered by Prof. Jaana Kekalenien, who provided a historical, critical reflection of realism in Interactive Information Retrieval Experimentation, while the second keynote was delivered by Prof. Maarten de Rijke, who argued for more Artificial Intelligence usage in IR solutions and deployments. The workshop was followed by a "Tour de Scotland" where delegates were taken from Glasgow to Aberdeen for the European Conference in Information Retrieval (ECIR 2017

An evaluation of the economic impact of broadband in Lincolnshire: updated final report

The Lincolnshire Broadband Initiative, ‘onlincolnshire’, was launched in 2003 to bring a range of broadband supply and demand stimulation activities to businesses across the county. The initiative has used £15 million of European funding, together with matched funding from Lincolnshire County Council, to support a series of significant Information and Communication Technology (ICT) interventions to provide support and financial assistance to eligible Lincolnshire businesses. The ‘onlincolnshire’ initiative has four long term strategic objectives. By 2010: • Lincolnshire will be the foremost rural County in the UK, with regards to ICT usage and skills and will have a commercial environment that embraces ICT; • The main employment sites and premises will have attracted increased and more diverse investment; • ICT will have made a major contribution to business competitiveness, expansion and diversification of the economy – measured through an increase in ICT related employment and a range of ICT based activities; • To have engaged individuals and employers in improving ICT skills to increase local competitiveness, raise the standards, participation and achievement in ICT throughout the County

Commodity Export Diversification in Rwanda - Many Export Discoveries with Little Scaling-Up

Increased diversification of commodity exports, and increased numbers of high-value commodity exports, are needed to generate employment and meet the Government of Rwanda´s targets for poverty reduction. This chapter presents evidence that increased diversification of exports is linked to increased export and GDP growth. Yet, commodity exports in Rwanda are concentrated in a few commodities. The relationship between export diversification and export growth in SSA confirms that for stable, sustainable, and higher export growth, export diversification is necessary. In addition to export promotion policies such as those which attract FDI, decision makers need to design policies to accelerate diversification of the export mix. The effect of diversification on export growth will be maximized if diversification shifts the export mix in the direction of manufactured or resource-based products (low or medium technology). This implies both sector specific public strategies that can influence the export mix; and second, public investments in human capital and supporting infrastructure.Rwanda; economic growth; export diversification; structural transformation

Integrated Delivery Networks: In Search of Benefits and Market Effects

Integrated Delivery Networks (IDNs) have very different stated purposes than mere collections of hospitals: to coordinate care across the continuum of health services and to manage population health. IDN advocates claim that these complex enterprises yield both societal benefits and performance advantages over less integrated competitors. The purpose of this analysis is to evaluate the evidence to support these claims.For the study, researchers performed a review of the academic literature on IDN performance, as well as an analysis of publicly available quality and financial data from 15 of the biggest not-for-profit IDNs in the U.S., including Sutter Health in Northern California. The authors compared the publicly available performance information on the IDNs' flagship hospital in its principal regional market with that flagship's most significant in-market competitor. The study found that it is possible for integrated delivery networks to offer meaningful benefits, but there is little evidence they have reduced costs or improved the quality of care. Findings include:Hospital-physician integration has raised physician costs, hospital prices and per capita medical care spending;Hospital integration into health plan operations and capitated contracting was not associated either with clinical efficiency or financial efficiencyProviders are likely to see a decrease in operating margins and return on capital as they invest in IDN developmen