Clustering Arabic Tweets for Sentiment Analysis

The focus of this study is to evaluate the impact of linguistic preprocessing and similarity functions for clustering Arabic Twitter tweets. The experiments apply an optimized version of the standard K-Means algorithm to assign tweets into positive and negative categories. The results show that root-based stemming has a significant advantage over light stemming in all settings. The Averaged Kullback-Leibler Divergence similarity function clearly outperforms the Cosine, Pearson Correlation, Jaccard Coefficient and Euclidean functions. The combination of the Averaged Kullback-Leibler Divergence and root-based stemming achieved the highest purity of 0.764 while the second-best purity was 0.719. These results are of importance as it is contrary to normal-sized documents where, in many information retrieval applications, light stemming performs better than root-based stemming and the Cosine function is commonly used

Clustering Arabic Tweets for Sentiment Analysis

The focus of this study is to evaluate the impact of linguistic preprocessing and similarity functions for clustering Arabic Twitter tweets. The experiments apply an optimized version of the standard K-Means algorithm to assign tweets into positive and negative categories. The results show that root-based stemming has a significant advantage over light stemming in all settings. The Averaged Kullback-Leibler Divergence similarity function clearly outperforms the Cosine, Pearson Correlation, Jaccard Coefficient and Euclidean functions. The combination of the Averaged Kullback-Leibler Divergence and root-based stemming achieved the highest purity of 0.764 while the second-best purity was 0.719. These results are of importance as it is contrary to normal-sized documents where, in many information retrieval applications, light stemming performs better than root-based stemming and the Cosine function is commonly used

Conceptualization of Computational Modeling Approaches and Interpretation of the Role of Neuroimaging Indices in Pathomechanisms for Pre-Clinical Detection of Alzheimer Disease

With swift advancements in next-generation sequencing technologies alongside the voluminous growth of biological data, a diversity of various data resources such as databases and web services have been created to facilitate data management, accessibility, and analysis. However, the burden of interoperability between dynamically growing data resources is an increasingly rate-limiting step in biomedicine, specifically concerning neurodegeneration. Over the years, massive investments and technological advancements for dementia research have resulted in large proportions of unmined data. Accordingly, there is an essential need for intelligent as well as integrative approaches to mine available data and substantiate novel research outcomes. Semantic frameworks provide a unique possibility to integrate multiple heterogeneous, high-resolution data resources with semantic integrity using standardized ontologies and vocabularies for context- specific domains. In this current work, (i) the functionality of a semantically structured terminology for mining pathway relevant knowledge from the literature, called Pathway Terminology System, is demonstrated and (ii) a context-specific high granularity semantic framework for neurodegenerative diseases, known as NeuroRDF, is presented. Neurodegenerative disorders are especially complex as they are characterized by widespread manifestations and the potential for dramatic alterations in disease progression over time. Early detection and prediction strategies through clinical pointers can provide promising solutions for effective treatment of AD. In the current work, we have presented the importance of bridging the gap between clinical and molecular biomarkers to effectively contribute to dementia research. Moreover, we address the need for a formalized framework called NIFT to automatically mine relevant clinical knowledge from the literature for substantiating high-resolution cause-and-effect models

Weaving the fabric of science: Dynamic network models of science's unfolding structure

AbstractScience is a complex system. Building on Latour's actor network theory, we model published science as a dynamic hypergraph and explore how this fabric provides a substrate for future scientific discovery. Using millions of abstracts from MEDLINE, we show that the network distance between biomedical things (i.e., people, methods, diseases, chemicals) is surprisingly small. We then show how science moves from questions answered in one year to problems investigated in the next through a weighted random walk model. Our analysis reveals intriguing modal dispositions in the way biomedical science evolves: methods play a bridging role and things of one type connect through things of another. This has the methodological implication that adding more node types to network models of science and other creative domains will likely lead to a superlinear increase in prediction and understanding

MLNet: a multi-level multimodal named entity recognition architecture

In the field of human–computer interaction, accurate identification of talking objects can help robots to accomplish subsequent tasks such as decision-making or recommendation; therefore, object determination is of great interest as a pre-requisite task. Whether it is named entity recognition (NER) in natural language processing (NLP) work or object detection (OD) task in the computer vision (CV) field, the essence is to achieve object recognition. Currently, multimodal approaches are widely used in basic image recognition and natural language processing tasks. This multimodal architecture can perform entity recognition tasks more accurately, but when faced with short texts and images containing more noise, we find that there is still room for optimization in the image-text-based multimodal named entity recognition (MNER) architecture. In this study, we propose a new multi-level multimodal named entity recognition architecture, which is a network capable of extracting useful visual information for boosting semantic understanding and subsequently improving entity identification efficacy. Specifically, we first performed image and text encoding separately and then built a symmetric neural network architecture based on Transformer for multimodal feature fusion. We utilized a gating mechanism to filter visual information that is significantly related to the textual content, in order to enhance text understanding and achieve semantic disambiguation. Furthermore, we incorporated character-level vector encoding to reduce text noise. Finally, we employed Conditional Random Fields for label classification task. Experiments on the Twitter dataset show that our model works to increase the accuracy of the MNER task

Application of digital pathology-based advanced analytics of tumour microenvironment organisation to predict prognosis and therapeutic response.

In recent years, the application of advanced analytics, especially artificial intelligence (AI), to digital H&E images, and other histological image types, has begun to radically change how histological images are used in the clinic. Alongside the recognition that the tumour microenvironment (TME) has a profound impact on tumour phenotype, the technical development of highly multiplexed immunofluorescence platforms has enhanced the biological complexity that can be captured in the TME with high precision. AI has an increasingly powerful role in the recognition and quantitation of image features and the association of such features with clinically important outcomes, as occurs in distinct stages in conventional machine learning. Deep-learning algorithms are able to elucidate TME patterns inherent in the input data with minimum levels of human intelligence and, hence, have the potential to achieve clinically relevant predictions and discovery of important TME features. Furthermore, the diverse repertoire of deep-learning algorithms able to interrogate TME patterns extends beyond convolutional neural networks to include attention-based models, graph neural networks, and multimodal models. To date, AI models have largely been evaluated retrospectively, outside the well-established rigour of prospective clinical trials, in part because traditional clinical trial methodology may not always be suitable for the assessment of AI technology. However, to enable digital pathology-based advanced analytics to meaningfully impact clinical care, specific measures of 'added benefit' to the current standard of care and validation in a prospective setting are important. This will need to be accompanied by adequate measures of explainability and interpretability. Despite such challenges, the combination of expanding datasets, increased computational power, and the possibility of integration of pre-clinical experimental insights into model development means there is exciting potential for the future progress of these AI applications. © 2023 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland