16,475 research outputs found
An Efficient Approach for Polyps Detection in Endoscopic Videos Based on Faster R-CNN
Polyp has long been considered as one of the major etiologies to colorectal
cancer which is a fatal disease around the world, thus early detection and
recognition of polyps plays a crucial role in clinical routines. Accurate
diagnoses of polyps through endoscopes operated by physicians becomes a
challenging task not only due to the varying expertise of physicians, but also
the inherent nature of endoscopic inspections. To facilitate this process,
computer-aid techniques that emphasize fully-conventional image processing and
novel machine learning enhanced approaches have been dedicatedly designed for
polyp detection in endoscopic videos or images. Among all proposed algorithms,
deep learning based methods take the lead in terms of multiple metrics in
evolutions for algorithmic performance. In this work, a highly effective model,
namely the faster region-based convolutional neural network (Faster R-CNN) is
implemented for polyp detection. In comparison with the reported results of the
state-of-the-art approaches on polyps detection, extensive experiments
demonstrate that the Faster R-CNN achieves very competing results, and it is an
efficient approach for clinical practice.Comment: 6 pages, 10 figures,2018 International Conference on Pattern
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Prospects for Theranostics in Neurosurgical Imaging: Empowering Confocal Laser Endomicroscopy Diagnostics via Deep Learning
Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence
imaging technology that has the potential to increase intraoperative precision,
extend resection, and tailor surgery for malignant invasive brain tumors
because of its subcellular dimension resolution. Despite its promising
diagnostic potential, interpreting the gray tone fluorescence images can be
difficult for untrained users. In this review, we provide a detailed
description of bioinformatical analysis methodology of CLE images that begins
to assist the neurosurgeon and pathologist to rapidly connect on-the-fly
intraoperative imaging, pathology, and surgical observation into a
conclusionary system within the concept of theranostics. We present an overview
and discuss deep learning models for automatic detection of the diagnostic CLE
images and discuss various training regimes and ensemble modeling effect on the
power of deep learning predictive models. Two major approaches reviewed in this
paper include the models that can automatically classify CLE images into
diagnostic/nondiagnostic, glioma/nonglioma, tumor/injury/normal categories and
models that can localize histological features on the CLE images using weakly
supervised methods. We also briefly review advances in the deep learning
approaches used for CLE image analysis in other organs. Significant advances in
speed and precision of automated diagnostic frame selection would augment the
diagnostic potential of CLE, improve operative workflow and integration into
brain tumor surgery. Such technology and bioinformatics analytics lend
themselves to improved precision, personalization, and theranostics in brain
tumor treatment.Comment: See the final version published in Frontiers in Oncology here:
https://www.frontiersin.org/articles/10.3389/fonc.2018.00240/ful
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The Computational Diet: A Review of Computational Methods Across Diet, Microbiome, and Health.
Food and human health are inextricably linked. As such, revolutionary impacts on health have been derived from advances in the production and distribution of food relating to food safety and fortification with micronutrients. During the past two decades, it has become apparent that the human microbiome has the potential to modulate health, including in ways that may be related to diet and the composition of specific foods. Despite the excitement and potential surrounding this area, the complexity of the gut microbiome, the chemical composition of food, and their interplay in situ remains a daunting task to fully understand. However, recent advances in high-throughput sequencing, metabolomics profiling, compositional analysis of food, and the emergence of electronic health records provide new sources of data that can contribute to addressing this challenge. Computational science will play an essential role in this effort as it will provide the foundation to integrate these data layers and derive insights capable of revealing and understanding the complex interactions between diet, gut microbiome, and health. Here, we review the current knowledge on diet-health-gut microbiota, relevant data sources, bioinformatics tools, machine learning capabilities, as well as the intellectual property and legislative regulatory landscape. We provide guidance on employing machine learning and data analytics, identify gaps in current methods, and describe new scenarios to be unlocked in the next few years in the context of current knowledge
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