Health Care Equity Through Intelligent Edge Computing and Augmented Reality/Virtual Reality: A Systematic Review

Intellectual capital is a scarce resource in the healthcare industry. Making the most of this resource is the first step toward achieving a completely intelligent healthcare system. However, most existing centralized and deep learning-based systems are unable to adapt to the growing volume of global health records and face application issues. To balance the scarcity of healthcare resources, the emerging trend of IoMT (Internet of Medical Things) and edge computing will be very practical and cost-effective. A full examination of the transformational role of intelligent edge computing in the IoMT era to attain health care equity is offered in this research. Intelligent edge computing-aided distribution and collaborative information management is a possible approach for a long-term digital healthcare system. Furthermore, IEC (Intelligent Edge Computing) encourages digital health data to be processed only at the edge, minimizing the amount of information exchanged with central servers/the internet. This significantly increases the privacy of digital health data. Another critical component of a sustainable healthcare system is affordability in digital healthcare. Affordability in digital healthcare is another key component of a sustainable healthcare system. Despite its importance, it has received little attention due to its complexity. In isolated and rural areas where expensive equipment is unavailable, IEC with AR / VR, also known as edge device shadow, can play a significant role in the inexpensive data collection process. Healthcare equity becomes a reality by combining intelligent edge device shadows and edge computing

DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'

Diagnosing bone and soft tissue neoplasms remains challenging because of the large number of subtypes, many of which lack diagnostic biomarkers. DNA methylation profiles have proven to be a reliable basis for the classification of brain tumours and, following this success, a DNA methylation-based sarcoma classification tool from the Deutsches Krebsforschungszentrum (DKFZ) in Heidelberg has been developed. In this study, we assessed the performance of their classifier on DNA methylation profiles of an independent data set of 986 bone and soft tissue tumours and controls. We found that the 'DKFZ Sarcoma Classifier' was able to produce a diagnostic prediction for 55% of the 986 samples, with 83% of these predictions concordant with the histological diagnosis. On limiting the validation to the 820 cases with histological diagnoses for which the DKFZ Classifier was trained, 61% of cases received a prediction, and the histological diagnosis was concordant with the predicted methylation class in 88% of these cases, findings comparable to those reported in the DKFZ Classifier paper. The classifier performed best when diagnosing mesenchymal chondrosarcomas (CHSs, 88% sensitivity), chordomas (85% sensitivity), and fibrous dysplasia (83% sensitivity). Amongst the subtypes least often classified correctly were clear cell CHSs (14% sensitivity), malignant peripheral nerve sheath tumours (27% sensitivity), and pleomorphic liposarcomas (29% sensitivity). The classifier predictions resulted in revision of the histological diagnosis in six of our cases. We observed that, although a higher tumour purity resulted in a greater likelihood of a prediction being made, it did not correlate with classifier accuracy. Our results show that the DKFZ Classifier represents a powerful research tool for exploring the pathogenesis of sarcoma; with refinement, it has the potential to be a valuable diagnostic tool

Deep learning : enhancing the security of software-defined networks

Software-defined networking (SDN) is a communication paradigm that promotes network flexibility and programmability by separating the control plane from the data plane. SDN consolidates the logic of network devices into a single entity known as the controller. SDN raises significant security challenges related to its architecture and associated characteristics such as programmability and centralisation. Notably, security flaws pose a risk to controller integrity, confidentiality and availability. The SDN model introduces separation of the forwarding and control planes. It detaches the control logic from switching and routing devices, forming a central plane or network controller that facilitates communications between applications and devices. The architecture enhances network resilience, simplifies management procedures and supports network policy enforcement. However, it is vulnerable to new attack vectors that can target the controller. Current security solutions rely on traditional measures such as firewalls or intrusion detection systems (IDS). An IDS can use two different approaches: signature-based or anomaly-based detection. The signature-based approach is incapable of detecting zero-day attacks, while anomaly-based detection has high false-positive and false-negative alarm rates. Inaccuracies related to false-positive attacks may have significant consequences, specifically from threats that target the controller. Thus, improving the accuracy of the IDS will enhance controller security and, subsequently, SDN security. A centralised network entity that controls the entire network is a primary target for intruders. The controller is located at a central point between the applications and the data plane and has two interfaces for plane communications, known as northbound and southbound, respectively. Communications between the controller, the application and data planes are prone to various types of attacks, such as eavesdropping and tampering. The controller software is vulnerable to attacks such as buffer and stack overflow, which enable remote code execution that can result in attackers taking control of the entire network. Additionally, traditional network attacks are more destructive. This thesis introduces a threat detection approach aimed at improving the accuracy and efficiency of the IDS, which is essential for controller security. To evaluate the effectiveness of the proposed framework, an empirical study of SDN controller security was conducted to identify, formalise and quantify security concerns related to SDN architecture. The study explored the threats related to SDN architecture, specifically threats originating from the existence of the control plane. The framework comprises two stages, involving the use of deep learning (DL) algorithms and clustering algorithms, respectively. DL algorithms were used to reduce the dimensionality of inputs, which were forwarded to clustering algorithms in the second stage. Features were compressed to a single value, simplifying and improving the performance of the clustering algorithm. Rather than using the output of the neural network, the framework presented a unique technique for dimensionality reduction that used a single value—reconstruction error—for the entire input record. The use of a DL algorithm in the pre-training stage contributed to solving the problem of dimensionality related to k-means clustering. Using unsupervised algorithms facilitated the discovery of new attacks. Further, this study compares generative energy-based models (restricted Boltzmann machines) with non-probabilistic models (autoencoders). The study implements TensorFlow in four scenarios. Simulation results were statistically analysed using a confusion matrix, which was evaluated and compared with similar related works. The proposed framework, which was adapted from existing similar approaches, resulted in promising outcomes and may provide a robust prospect for deployment in modern threat detection systems in SDN. The framework was implemented using TensorFlow and was benchmarked to the KDD99 dataset. Simulation results showed that the use of the DL algorithm to reduce dimensionality significantly improved detection accuracy and reduced false-positive and false-negative alarm rates. Extensive simulation studies on benchmark tasks demonstrated that the proposed framework consistently outperforms all competing approaches. This improvement is a further step towards the development of a reliable IDS to enhance the security of SDN controllers

Security Threats to 5G Networks for Social Robots in Public Spaces: A Survey

This paper surveys security threats to 5G-enabled wireless access networks for social robots in public spaces (SRPS). The use of social robots (SR) in public areas requires specific Quality of Service (QoS) planning to meet its unique requirements. Its 5G threat landscape entails more than cybersecurity threats that most previous studies focus on. This study examines the 5G wireless RAN for SRPS from three perspectives: SR and wireless access points, the ad hoc network link between SR and user devices, and threats to SR and users’ communication equipment. The paper analyses the security threats to confidentiality, integrity, availability, authentication, authorisation, and privacy from the SRPS security objectives perspective. We begin with an overview of SRPS use cases and access network requirements, followed by 5G security standards, requirements, and the need for a more representative threat landscape for SRPS. The findings confirm that the RAN of SRPS is most vulnerable to physical, side-channel, intrusion, injection, manipulation, and natural and malicious threats. The paper presents existing mitigation to the identified attacks and recommends including physical level security (PLS) and post-quantum cryptography in the early design of SRPS. The insights from this survey will provide valuable risk assessment and management input to researchers, industrial practitioners, policymakers, and other stakeholders of SRPS.publishedVersio

Mobile Oriented Future Internet (MOFI)

This Special Issue consists of seven papers that discuss how to enhance mobility management and its associated performance in the mobile-oriented future Internet (MOFI) environment. The first two papers deal with the architectural design and experimentation of mobility management schemes, in which new schemes are proposed and real-world testbed experimentations are performed. The subsequent three papers focus on the use of software-defined networks (SDN) for effective service provisioning in the MOFI environment, together with real-world practices and testbed experimentations. The remaining two papers discuss the network engineering issues in newly emerging mobile networks, such as flying ad-hoc networks (FANET) and connected vehicular networks

How 5G wireless (and concomitant technologies) will revolutionize healthcare?

The need to have equitable access to quality healthcare is enshrined in the United Nations (UN) Sustainable Development Goals (SDGs), which defines the developmental agenda of the UN for the next 15 years. In particular, the third SDG focuses on the need to “ensure healthy lives and promote well-being for all at all ages”. In this paper, we build the case that 5G wireless technology, along with concomitant emerging technologies (such as IoT, big data, artificial intelligence and machine learning), will transform global healthcare systems in the near future. Our optimism around 5G-enabled healthcare stems from a confluence of significant technical pushes that are already at play: apart from the availability of high-throughput low-latency wireless connectivity, other significant factors include the democratization of computing through cloud computing; the democratization of Artificial Intelligence (AI) and cognitive computing (e.g., IBM Watson); and the commoditization of data through crowdsourcing and digital exhaust. These technologies together can finally crack a dysfunctional healthcare system that has largely been impervious to technological innovations. We highlight the persistent deficiencies of the current healthcare system and then demonstrate how the 5G-enabled healthcare revolution can fix these deficiencies. We also highlight open technical research challenges, and potential pitfalls, that may hinder the development of such a 5G-enabled health revolution

Exploiting the power of multiplicity: a holistic survey of network-layer multipath

The Internet is inherently a multipath network: For an underlying network with only a single path, connecting various nodes would have been debilitatingly fragile. Unfortunately, traditional Internet technologies have been designed around the restrictive assumption of a single working path between a source and a destination. The lack of native multipath support constrains network performance even as the underlying network is richly connected and has redundant multiple paths. Computer networks can exploit the power of multiplicity, through which a diverse collection of paths is resource pooled as a single resource, to unlock the inherent redundancy of the Internet. This opens up a new vista of opportunities, promising increased throughput (through concurrent usage of multiple paths) and increased reliability and fault tolerance (through the use of multiple paths in backup/redundant arrangements). There are many emerging trends in networking that signify that the Internet's future will be multipath, including the use of multipath technology in data center computing; the ready availability of multiple heterogeneous radio interfaces in wireless (such as Wi-Fi and cellular) in wireless devices; ubiquity of mobile devices that are multihomed with heterogeneous access networks; and the development and standardization of multipath transport protocols such as multipath TCP. The aim of this paper is to provide a comprehensive survey of the literature on network-layer multipath solutions. We will present a detailed investigation of two important design issues, namely, the control plane problem of how to compute and select the routes and the data plane problem of how to split the flow on the computed paths. The main contribution of this paper is a systematic articulation of the main design issues in network-layer multipath routing along with a broad-ranging survey of the vast literature on network-layer multipathing. We also highlight open issues and identify directions for future work

Human-Computer Interaction: Security Aspects

Along with the rapid development of intelligent information age, users are having a growing interaction with smart devices. Such smart devices are interconnected together in the Internet of Things (IoT). The sensors of IoT devices collect information about users' behaviors from the interaction between users and devices. Since users interact with IoT smart devices for the daily communication and social network activities, such interaction generates a huge amount of network traffic. Hence, users' behaviors are playing an important role in the security of IoT smart devices, and the security aspects of Human-Computer Interaction are becoming significant. In this dissertation, we provide a threefold contribution: (1) we review security challenges of HCI-based authentication, and design a tool to detect deceitful users via keystroke dynamics; (2) we present the impact of users' behaviors on network traffic, and propose a framework to manage such network traffic; (3) we illustrate a proposal for energy-constrained IoT smart devices to be resilient against energy attack and efficient in network communication. More in detail, in the first part of this thesis, we investigate how users' behaviors impact on the way they interact with a device. Then we review the work related to security challenges of HCI-based authentication on smartphones, and Brain-Computer Interfaces (BCI). Moreover, we design a tool to assess the truthfulness of the information that users input using a computer keyboard. This tool is based on keystroke dynamics and it relies on machine learning technique to achieve this goal. To the best of our knowledge, this is the first work that associates the typing users' behaviors with the production of deceptive personal information. We reached an overall accuracy of 76% in the classification of a single answer as truthful or deceptive. In the second part of this thesis, we review the analysis of network traffic, especially related to the interaction between mobile devices and users. Since the interaction generates a huge amount of network traffic, we propose an innovative framework, GolfEngine, to manage and control the impact of users behavior on the network relying on Software Defined Networking (SDN) techniques. GolfEngine provides users a tool to build their security applications and offers Graphical User Interface (GUI) for managing and monitoring the network. In particular, GolfEngine provides the function of checking policy conflicts when users design security applications and the mechanism to check data storage redundancy. GolfEngine not only prevents the malicious inputting policies but also it enforces the security about network management of network traffic. The results of our simulation underline that GolfEngine provides an efficient, secure, and robust performance for managing network traffic via SDN. In the third and last part of this dissertation, we analyze the security aspects of battery-equipped IoT devices from the energy consumption perspective. Although most of the energy consumption of IoT devices is due to user interaction, there is still a significant amount of energy consumed by point-to-point communication and IoT network management. In this scenario, an adversary may hijack an IoT device and conduct a Denial of Service attack (DoS) that aims to run out batteries of other devices. Therefore, we propose EnergIoT, a novel method based on energetic policies that prevent such attacks and, at the same time, optimizes the communication between users and IoT devices, and extends the lifetime of the network. EnergIoT relies on a hierarchical clustering approach, based on different duty cycle ratios, to maximize network lifetime of energy-constrained smart devices. The results show that EnergIoT enhances the security and improves the network lifetime by 32%, compared to the earlier used approach, without sacrificing the network performance (i.e., end-to-end delay)