From “Oh, OK” to “Ah, yes” to “Aha!”: Hyper-systemizing and the rewards of insight\ud

Hyper-systemizers are individuals displaying an unusually strong bias toward systemizing, i.e. toward explaining events and solving problems by appeal to mechanisms that do not involve intentions or agency. Hyper-systemizing in combination with deficit mentalizing ability typically presents clinically as an autistic spectrum disorder; however, the development of hyper-systemizing in combination with normal-range mentalizing ability is not well characterized. Based on a review and synthesis of clinical, observational, experimental, and neurofunctional studies, it is hypothesized that repeated episodes of insightful problem solving by systemizing result in attentional and motivational sensitization toward further systemizing via progressive and chronic deactivation of the default network. This hypothesis is distinguished from alternatives, and its correlational and causal implications are discussed. Predictions of the default-deactivation model accessible to survey-based instruments, standard cognitive measures and neurofunctional methods are outlined, and evidence pertaining to them considered

The role of response mechanisms in determining reaction time performance: Piéron’s Law revisited

A response mechanism takes evaluations of the importance of potential actions and selects the most suitable. Response mechanism function is a nontrivial problem that has not received the attention it deserves within cognitive psychology. In this article, we make a case for the importance of considering response mechanism function as a constraint on cognitive processes and emphasized links with the wider problem of behavioral action selection. First, we show that, contrary to previous suggestions, a well–known model of the Stroop task (Cohen, Dunbar, & McClelland, 1990) relies on the response mechanism for a key feature of its results—the interference–facilitation asymmetry. Second, we examine a variety of response mechanisms (including that in the model of Cohen et al., 1990) and show that they all follow a law analogous to Piéron's law in relating their input to reaction time. In particular, this is true of a decision mechanism not designed to explain RT data but based on a proposed solution to the general problem of action selection and grounded in the neurobiology of the vertebrate basal ganglia. Finally, we show that the dynamics of simple artificial neurons also support a Piéron–like law

Occlusion-related lateral connections stabilize kinetic depth stimuli through perceptual coupling

Local sensory information is often ambiguous forcing the brain to integrate spatiotemporally separated information for stable conscious perception. Lateral connections between clusters of similarly tuned neurons in the visual cortex are a potential neural substrate for the coupling of spatially separated visual information. Ecological optics suggests that perceptual coupling of visual information is particularly beneficial in occlusion situations. Here we present a novel neural network model and a series of human psychophysical experiments that can together explain the perceptual coupling of kinetic depth stimuli with activity-driven lateral information sharing in the far depth plane. Our most striking finding is the perceptual coupling of an ambiguous kinetic depth cylinder with a coaxially presented and disparity defined cylinder backside, while a similar frontside fails to evoke coupling. Altogether, our findings are consistent with the idea that clusters of similarly tuned far depth neurons share spatially separated motion information in order to resolve local perceptual ambiguities. The classification of far depth in the facilitation mechanism results from a combination of absolute and relative depth that suggests a functional role of these lateral connections in the perception of partially occluded objects

Neural correlates of intrusion of emotion words in a modified Stroop task

Behavioural studies have demonstrated that the emotional Stroop task is a valuable tool for investigating emotion-attention interactions in a variety of healthy and clinical populations, showing that participants are typically more distracted by negative stimuli as compared to neutral or positive stimuli. The main aim of this study was to find and examine the neural correlates of this greater intrusion from negative emotional stimuli. Reliable reaction time (RT) and event-related potential (ER-P) data were collected from 23 participants who performed a manual emotional Stroop, task with short (40 ins) and long (500 ms) inter-trial intervals. In the short interval condition, participants were found to produce longer RTs for negative than neutral words, suggesting that these stimuli were more difficult to ignore. This RT effect disappeared in the long interval condition, although larger PI amplitudes were found for the negative words. This suggests that differences in early attention allocation may be unrelated to the degree of intrusion at the behavioural level. In addition, a larger negative slow wave around 300-700 ms post-stimulus was observed in the long interval condition, but only for those negative words that produced prolonged RTs as compared to their matched controls. This late and broadly distributed effect is believed to reflect suppression of meaning representations

Glucoregulatory and order effects on verbal episodic memory in healthy adolescents after oral glucose administration

The ingestion of oral glucose has been observed to facilitate memory performance in both elderly individuals and in young adults. However, fewer studies have investigated the effect of glucose on memory in children or adolescents. In the present study, the ingestion of a glucose laden drink was observed to enhance verbal episodic memory performance in healthy adolescents under conditions of divided attention, relative to a placebo drink. Further analyses found that this glucose memory facilitation effect was observed only in adolescents exhibiting better glucoregulatory efficiency. These findings demonstrate that the glucose memory facilitation effect can be generalised to younger individuals. The importance of controlling for treatment order in within-subjects designs investigating the glucose memory enhancement effect is also discussed

Integrative priming occurs rapidly and uncontrollably during lexical processing

Lexical priming, whereby a prime word facilitates recognition of a related target word (e.g., nurse ? doctor), is typically attributed to association strength, semantic similarity, or compound familiarity. Here, the authors demonstrate a novel type of lexical priming that occurs among unassociated, dissimilar, and unfamiliar concepts (e.g., horse ? doctor). Specifically, integrative priming occurs when a prime word can be easily integrated with a target word to create a unitary representation. Across several manipulations of timing (stimulus onset asynchrony) and list context (relatedness proportion), lexical decisions for the target word were facilitated when it could be integrated with the prime word. Moreover, integrative priming was dissociated from both associative priming and semantic priming but was comparable in terms of both prevalence (across participants) and magnitude (within participants). This observation of integrative priming challenges present models of lexical priming, such as spreading activation, distributed representation, expectancy, episodic retrieval, and compound cue models. The authors suggest that integrative priming may be explained by a role activation model of relational integration

Student Attitudes Towards Drinking Behaviors

The literature is relatively inconclusive regarding predictors of alcohol use; while some studies have demonstrated an association between high levels of social interaction and increased alcohol use, others have shown that a lack of social support is linked to drinking heavily. The current study was conducted with students at the University of New Hampshire; participants’ attitudes towards alcohol were assessed along with many psychosocial factors. Low levels of conscientiousness, parent and high school influence, frequently attending parties, and friend influence were most highly predictive of positive attitudes towards alcohol; multiple regression of these factors accounted for 30.1% of the variance. Alternatively, negative attitudes towards alcohol were most highly predicted by high levels of conscientiousness and infrequently attending parties. Positive and negative attitudes were not highly correlated with one another; therefore, some students had both highly positive and highly negative attitudes toward alcohol. This group, with conflicting attitudes toward alcohol use, is of particular interest

Changes in synaptic transmission and protein expression in the brains of adult offspring after prenatal inhibition of the kynurenine pathway

During early brain development, N-methyl-d-aspartate (NMDA) receptors are involved in cell migration, neuritogenesis, axon guidance and synapse formation, but the mechanisms which regulate NMDA receptor density and function remain unclear. The kynurenine pathway of tryptophan metabolism includes an agonist (quinolinic acid) and an antagonist (kynurenic acid) at NMDA receptors and we have previously shown that inhibition of the pathway using the kynurenine-3-monoxygenase inhibitor Ro61-8048 in late gestation produces rapid changes in protein expression in the embryos and effects on synaptic transmission lasting until postnatal day 21 (P21). The present study sought to determine whether any of these effects are maintained into adulthood. After prenatal injections of Ro61-8048 the litter was allowed to develop to P60 when some offspring were euthanized and the brains removed for examination. Analysis of protein expression by Western blotting revealed significantly reduced expression of the GluN2A subunit (32%) and the morphogenetic protein sonic hedgehog (31%), with a 29% increase in the expression of doublecortin, a protein associated with neurogenesis. No changes were seen in mRNA abundance using quantitative real-time polymerase chain reaction. Neuronal excitability was normal in the CA1 region of hippocampal slices but paired-pulse stimulation revealed less inhibition at short interpulse intervals. The amount of long-term potentiation was decreased by 49% in treated pups and recovery after low-frequency stimulation was delayed. The results not only strengthen the view that basal, constitutive kynurenine metabolism is involved in normal brain development, but also show that changes induced prenatally can affect the brains of adult offspring and those changes are quite different from those seen previously at weaning (P21). Those changes may be mediated by altered expression of NMDAR subunits and sonic hedgehog

The Empathy Imbalance Hypothesis of Autism: A Theoretical Approach to Cognitive and Emotional Empathy in Autistic Development

There has been a widely held belief that people with autism spectrum disorders lack empathy. This article examines the empathy imbalance hypothesis (EIH) of autism. According to this account, people with autism have a deficit of cognitive empathy but a surfeit of emotional empathy. The behavioral characteristics of autism might be generated by this imbalance and a susceptibility to empathic overarousal. The EIH builds on the theory of mind account and provides an alternative to the extreme-male-brain theory of autism. Empathy surfeit is a recurrent theme in autistic narratives, and empirical evidence for the EIH is growing. A modification of the pictorial emotional Stroop paradigm could facilitate an experimental test of the EIH

The Richness of Inner Experience: Relating Styles of Daydreaming to Creative Processes.

Psychologists have long hypothesized that daydreaming (i.e., engaging in stimulus-independent, task-unrelated thoughts and images) may facilitate creativity, but evidence for this hypothesis has been mixed. We propose that, to fully understand the relationship between daydreaming and creativity, it is essential to distinguish between different creative processes as well as between alternative styles of daydreaming. A prominent distinction in creativity research is that between analytic problem solving, which involves incremental and largely conscious processes, and insight, which is characterized by the spontaneity with which an idea springs to mind. In this aspect, insight resembles daydreaming. Indeed, recent evidence has linked daydreaming to creative performance. But like creativity, daydreaming is a multifaceted concept. Daydreams vary in style and content, a fact that is receiving little attention in contemporary research. Not all kinds of daydreaming are likely to have the same effects on creativity. We discuss different factors prevalent in people's daydreaming, such as mood, attentional focus, and intentionality, and consider how these factors may be related to creative processes. We further discuss implications for ways to enhance creativity through deliberate daydreaming practice