16,519 research outputs found
Motion compensated micro-CT reconstruction for in-situ analysis of dynamic processes
This work presents a framework to exploit the synergy between Digital Volume Correlation ( DVC) and iterative CT reconstruction to enhance the quality of high-resolution dynamic X-ray CT (4D-mu CT) and obtain quantitative results from the acquired dataset in the form of 3D strain maps which can be directly correlated to the material properties. Furthermore, we show that the developed framework is capable of strongly reducing motion artifacts even in a dataset containing a single 360 degrees rotation
Brain MRI Super Resolution Using 3D Deep Densely Connected Neural Networks
Magnetic resonance image (MRI) in high spatial resolution provides detailed
anatomical information and is often necessary for accurate quantitative
analysis. However, high spatial resolution typically comes at the expense of
longer scan time, less spatial coverage, and lower signal to noise ratio (SNR).
Single Image Super-Resolution (SISR), a technique aimed to restore
high-resolution (HR) details from one single low-resolution (LR) input image,
has been improved dramatically by recent breakthroughs in deep learning. In
this paper, we introduce a new neural network architecture, 3D Densely
Connected Super-Resolution Networks (DCSRN) to restore HR features of
structural brain MR images. Through experiments on a dataset with 1,113
subjects, we demonstrate that our network outperforms bicubic interpolation as
well as other deep learning methods in restoring 4x resolution-reduced images.Comment: Accepted by ISBI'1
CT dose reduction factors in the thousands using X-ray phase contrast
Phase-contrast X-ray imaging can improve the visibility of weakly absorbing
objects (e.g. soft tissues) by an order of magnitude or more compared to
conventional radiographs. Previously, it has been shown that combining phase
retrieval with computed tomography (CT) can increase the signal-to-noise ratio
(SNR) by up to two orders of magnitude over conventional CT at the same
radiation dose, without loss of image quality. Our experiments reveal that as
radiation dose decreases, the relative improvement in SNR increases. We
discovered this enhancement can be traded for a reduction in dose greater than
the square of the gain in SNR. Upon reducing the dose 300 fold, the
phase-retrieved SNR was still almost 10 times larger than the absorption
contrast data. This reveals the potential for dose reduction factors in the
tens of thousands without loss in image quality, which would have a profound
impact on medical and industrial imaging applications
PVR: Patch-to-Volume Reconstruction for Large Area Motion Correction of Fetal MRI
In this paper we present a novel method for the correction of motion
artifacts that are present in fetal Magnetic Resonance Imaging (MRI) scans of
the whole uterus. Contrary to current slice-to-volume registration (SVR)
methods, requiring an inflexible anatomical enclosure of a single investigated
organ, the proposed patch-to-volume reconstruction (PVR) approach is able to
reconstruct a large field of view of non-rigidly deforming structures. It
relaxes rigid motion assumptions by introducing a specific amount of redundant
information that is exploited with parallelized patch-wise optimization,
super-resolution, and automatic outlier rejection. We further describe and
provide an efficient parallel implementation of PVR allowing its execution
within reasonable time on commercially available graphics processing units
(GPU), enabling its use in the clinical practice. We evaluate PVR's
computational overhead compared to standard methods and observe improved
reconstruction accuracy in presence of affine motion artifacts of approximately
30% compared to conventional SVR in synthetic experiments. Furthermore, we have
evaluated our method qualitatively and quantitatively on real fetal MRI data
subject to maternal breathing and sudden fetal movements. We evaluate
peak-signal-to-noise ratio (PSNR), structural similarity index (SSIM), and
cross correlation (CC) with respect to the originally acquired data and provide
a method for visual inspection of reconstruction uncertainty. With these
experiments we demonstrate successful application of PVR motion compensation to
the whole uterus, the human fetus, and the human placenta.Comment: 10 pages, 13 figures, submitted to IEEE Transactions on Medical
Imaging. v2: wadded funders acknowledgements to preprin
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