2,669 research outputs found
Big Data as a Driver for Clinical Decision Support Systems: A Learning Health Systems Perspective
Big data technologies are nowadays providing health care with powerful instruments to gather and analyze large volumes of heterogeneous data collected for different purposes, including clinical care, administration, and research. This makes possible to design IT infrastructures that favor the implementation of the so-called "Learning Healthcare System Cycle," where healthcare practice and research are part of a unique and synergic process. In this paper we highlight how "Big Data enabled" integrated data collections may support clinical decision-making together with biomedical research. Two effective implementations are reported, concerning decision support in Diabetes and in Inherited Arrhythmogenic Diseases
Semantics-Empowered Big Data Processing with Applications
We discuss the nature of Big Data and address the role of semantics in analyzing and processing Big Data that arises in the context of Physical-Cyber-Social Systems. We organize our research around the Five Vs of Big Data, where four of the Vs are harnessed to produce the fifth V - value. To handle the challenge of Volume, we advocate semantic perception that can convert low-level observational data to higher-level abstractions more suitable for decision-making. To handle the challenge of Variety, we resort to the use of semantic models and annotations of data so that much of the intelligent processing can be done at a level independent of heterogeneity of data formats and media. To handle the challenge of Velocity, we seek to use continuous semantics capability to dynamically create event or situation specific models and recognize relevant new concepts, entities and facts. To handle Veracity, we explore the formalization of trust models and approaches to glean trustworthiness. The above four Vs of Big Data are harnessed by the semantics-empowered analytics to derive value for supporting practical applications transcending physical-cyber-social continuum
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System Architecture of A European Platform for Health Policy Decision Making: MIDAS
Background: Healthcare data is a rich yet underutilized resource due to its disconnected, heterogeneous nature. A means of connecting healthcare data and integrating it with additional open and social data in a secure way can support the monumental challenge policy-makers face in safely accessing all relevant data to assist in managing the health and wellbeing of all. The goal of this study was to develop a novel health data platform within the MIDAS (Meaningful Integration of Data Analytics and Services) project, that harnesses the potential of latent healthcare data in combination with open and social data to support evidence-based health policy decision-making in a privacy-preserving manner. Methods: The MIDAS platform was developed in an iterative and collaborative way with close involvement of academia, industry, healthcare staff and policy-makers, to solve tasks including data storage, data harmonization, data analytics and visualizations, and open and social data analytics. The platform has been piloted and tested by health departments in four European countries, each focusing on different region-specific health challenges and related data sources. Results: A novel health data platform solving the needs of Public Health decision-makers was successfully implemented within the four pilot regions connecting heterogeneous healthcare datasets and open datasets and turning large amounts of previously isolated data into actionable information allowing for evidence-based health policy-making and risk stratification through the application and visualization of advanced analytics. Conclusions: The MIDAS platform delivers a secure, effective and integrated solution to deal with health data, providing support for health policy decision-making, planning of public health activities and the implementation of the Health in All Policies approach. The platform has proven transferable, sustainable and scalable across policies, data and regions
ML-MEDIC: A Preliminary Study of an Interactive Visual Analysis Tool Facilitating Clinical Applications of Machine Learning for Precision Medicine
Accessible interactive tools that integrate machine learning methods with clinical research and reduce the programming experience required are needed to move science forward. Here, we present Machine Learning for Medical Exploration and Data-Inspired Care (ML-MEDIC), a point-and-click, interactive tool with a visual interface for facilitating machine learning and statistical analyses in clinical research. We deployed ML-MEDIC in the American Heart Association (AHA) Precision Medicine Platform to provide secure internet access and facilitate collaboration. ML-MEDIC’s efficacy for facilitating the adoption of machine learning was evaluated through two case studies in collaboration with clinical domain experts. A domain expert review was also conducted to obtain an impression of the usability and potential limitations
Linear discriminant analysis and principal component analysis to predict coronary artery disease
Coronary artery disease is one of the most prevalent chronic pathologies in the modern world, leading to the deaths of thousands of people, both in the United States and in Europe. This article reports the use of data mining techniques to analyse a population of 10,265 people who were evaluated by the Department of Advanced Biomedical Sciences for myocardial ischaemia. Overall, 22 features are extracted, and linear discriminant analysis is implemented twice through both the Knime analytics platform and R statistical programming language to classify patients as either normal or pathological. The former of these analyses includes only classification, while the latter method includes principal component analysis before classification to create new features. The classification accuracies obtained for these methods were 84.5 and 86.0 per cent, respectively, with a specificity over 97 per cent and a sensitivity between 62 and 66 per cent. This article presents a practical implementation of traditional data mining techniques that can be used to help clinicians in decision-making; moreover, principal component analysis is used as an algorithm for feature reduction
Orthodontics in the era of big data analytics
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149344/1/ocr12279_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149344/2/ocr12279.pd
Design, implementation and realization of an integrated platform dedicated to e-public health, for analysing health data and supporting the management control in healthcare companies.
In healthcare, the information is a fundamental aspect and the human body is the major source of every kind of data: the challenge is to benefit from this huge amount of unstructured data by applying technologic solutions, called Big Data Analysis, that allows the management of data and the extraction of information through informatic systems. This thesis aims to introduce a technologic solution made up of two open source platforms: Power BI and Knime Analytics Platform. First, the importance, the role and the processes of business intelligence and machine learning in healthcare will be discussed; secondly, the platforms will be described, particularly enhancing their feasibility and capacities. Then, the clinical specialties, where they have been applied, will be shown by highlighting the international literature that have been produced: neurology, cardiology, oncology, fetal-monitoring and others. An application in the current pandemic situation due to SARS-CoV-2 will be described by using more than 50000 records: a cascade of 3 platforms helping health facilities to deal with the current worldwide pandemic.
Finally, the advantages, the disadvantages, the limitations and the future developments in this framework will be discussed while the architectural technologic solution containing a data warehouse, a platform to collect data, two platforms to analyse health and management data and the possible applications will be shown
The Revolution Lean Six Sigma 4.0
Industry 4.0 makes a factory smart by applying advanced information systems and future-oriented technologies. Today, thanks to the application of the most innovative digital technologies offered by the new Industry 4.0 paradigm, in this Fourth Industrial Revolution, there is a significant “evolution” of many methodologies of Continuous Improvement, such as, e.g., Lean Six Sigma (LSS). Most of the tools of Lean Six Sigma relies on data to know in depth problems: data is necessary to drive any process improvement. The key issue is based on data integrity and on real time data. The aim of this paper consists of proving the efficiency of the so called “Lean Six Sigma 4.0”. This paper deals with engineering approaches, here applied in HealthCare environment, in order to optimise the services supply process and to reduce the waste of resources (human and/or material), while improving the Quality of Experience (QoE) of the patients. Indeed, it has been proved that the huge growth in the HealthCare costs is due to inefficient use of available resources and not-optimised service processes. Applying Lean Six Sigma 4.0 it is possible to reduce HealthCare costs, improving at the same time the QoE perceived by the patient
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