Research Of Sensomotor Reaction, Memory And Attention Indicies Under Sensory Deprivation

The article considers the influence of sensory (visual and auditory) deprivation on a sensorimotor response, memory, and attention among 8-11 years old children. The literature review concludes that sensory deprivation causes discomfort and problems in perceiving of reality. Also, under the influence of various factors that damage body structures, compensatory reactions are launched to compensate for impaired functions. The processes that provide the body with the restoration of lost structures and impaired functions of the pathology are called «compensatory-adaptive processes». Having conducted statistical analysis of the obtained data of latent periods of different sensomotor responses among children with sensory deprivation and the control group, it is seen, that the level of stimuli in the form of figures was higher among children with hearing impairments, and in the form of sounds – in the group of children with visual impairments. According to the results of our study, we can assume that in groups of children with sensory deprivation the process of compensating the impaired function of a particular analyzer takes place at the expense of another one

Labelling of liposomes with intercalating perylene fluorescent dyes

The high fluorescent potential and the exceptional photostability of lipophilic derivatives of perylene-3,4:9,10-bis(dicarboximides) are utilized for the fluorescence-labelling of liposomes. The preparation of the liposomes is affected by supersonic starting from a lipid mixture consisting of the matrix lipids soy lecithin, cholesterol, -tocopherol and the perylene dyes. From a multitude of perylene derivatives investigated only those are optimally incorporated inot the bilayer membrane of unilamellar liposomes which are substituted at both nitrogen atoms by one or two linear hydrocarbon groups. In order to attain an optimal fluorescent quantum yield, about 200 to 300 dye molecules can be incorporated per liposome. The liposomes thus obtained have a diameter of about 70 to 80 nm, are homogeneous and may be stored for more than seven months. Neither the fluorescent properties nor the stability of these liposomes are influenced by the additional incorporation of various ara C-derivatives and lipophilic anchor groups which subsequently enable the coupling of antibodies to the liposomes. As the water-insoluble perylene dyes are incorporated into the bilayer membrane, the aqueous inner volume of the liposomes remains available for a fruther utilization