Cyber Security of Critical Infrastructures

Critical infrastructures are vital assets for public safety, economic welfare, and the national security of countries. The vulnerabilities of critical infrastructures have increased with the widespread use of information technologies. As Critical National Infrastructures are becoming more vulnerable to cyber-attacks, their protection becomes a significant issue for organizations as well as nations. The risks to continued operations, from failing to upgrade aging infrastructure or not meeting mandated regulatory regimes, are considered highly significant, given the demonstrable impact of such circumstances. Due to the rapid increase of sophisticated cyber threats targeting critical infrastructures with significant destructive effects, the cybersecurity of critical infrastructures has become an agenda item for academics, practitioners, and policy makers. A holistic view which covers technical, policy, human, and behavioural aspects is essential to handle cyber security of critical infrastructures effectively. Moreover, the ability to attribute crimes to criminals is a vital element of avoiding impunity in cyberspace. In this book, both research and practical aspects of cyber security considerations in critical infrastructures are presented. Aligned with the interdisciplinary nature of cyber security, authors from academia, government, and industry have contributed 13 chapters. The issues that are discussed and analysed include cybersecurity training, maturity assessment frameworks, malware analysis techniques, ransomware attacks, security solutions for industrial control systems, and privacy preservation methods

Antioxidant and DPPH-Scavenging Activities of Compounds and Ethanolic Extract of the Leaf and Twigs of Caesalpinia bonduc L. Roxb.

Antioxidant effects of ethanolic extract of Caesalpinia bonduc and its isolated bioactive compounds were evaluated in vitro. The compounds included two new cassanediterpenes, 1α,7α-diacetoxy-5α,6β-dihydroxyl-cass-14(15)-epoxy-16,12-olide (1)and 12α-ethoxyl-1α,14β-diacetoxy-2α,5α-dihydroxyl cass-13(15)-en-16,12-olide(2); and others, bonducellin (3), 7,4’-dihydroxy-3,11-dehydrohomoisoflavanone (4), daucosterol (5), luteolin (6), quercetin-3-methyl ether (7) and kaempferol-3-O-α-L-rhamnopyranosyl-(1Ç2)-β-D-xylopyranoside (8). The antioxidant properties of the extract and compounds were assessed by the measurement of the total phenolic content, ascorbic acid content, total antioxidant capacity and 1-1-diphenyl-2-picryl hydrazyl (DPPH) and hydrogen peroxide radicals scavenging activities.Compounds 3, 6, 7 and ethanolic extract had DPPH scavenging activities with IC50 values of 186, 75, 17 and 102 μg/ml respectively when compared to vitamin C with 15 μg/ml. On the other hand, no significant results were obtained for hydrogen peroxide radical. In addition, compound 7 has the highest phenolic content of 0.81±0.01 mg/ml of gallic acid equivalent while compound 8 showed the highest total antioxidant capacity with 254.31±3.54 and 199.82±2.78 μg/ml gallic and ascorbic acid equivalent respectively. Compound 4 and ethanolic extract showed a high ascorbic acid content of 2.26±0.01 and 6.78±0.03 mg/ml respectively.The results obtained showed the antioxidant activity of the ethanolic extract of C. bonduc and deduced that this activity was mediated by its isolated bioactive compounds