388 research outputs found

    Report Dagstuhl Seminar 10402 - Working Group on Fundamental Limits and Opportunities

    Get PDF
    This working group investigated first steps towards finding a theoretical foundation for inter-vehicle communication. The main outcome is a sketch of a roadmap for future work in this direction

    10402 Abstracts Collection and Executive Summary -- Inter-Vehicular Communication

    Get PDF
    From October 3 to October 6, 2010, the Dagstuhl Seminar 10402 ``Inter-Vehicular Communication\u27\u27 was held in Schloss Dagstuhl~--~Leibniz Center for Informatics. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar are put together in this paper. The first section describes the seminar topics and goals in general

    Opportunities for knowledge co-production across the energy-food-water nexus: Making interdisciplinary approaches work for better climate decision making

    Get PDF
    The relationship between the energy-food-water nexus and the climate is non-linear, multi-sectoral and time sensitive, incorporating aspects of complexity and risk in climate related decision-making. This paper seeks to explore how knowledge co-production can help identify opportunities for building more effective, sustainable, inclusive and legitimate decision making processes on climate change. This would enable more resilient responses to climate risks impacting the nexus while increasing transparency, communication and trust among key actors. We do so by proposing the operationalization of an interdisciplinary approach of analysis applying the novel methodology developed in Howarth and Monasterolo (2016). Through a bottom-up, participative approach, we present results of five themed workshops organized in the UK (focusing on: shocks and hazards, infrastructure, local economy, governance and governments, finance and insurance) featuring 78 stakeholders from academia, government and industry. We present participant's perceptions of opportunities that can emerge from climate and weather shocks across the energy-food-water nexus. We explore opportunities offered by the development and deployment of a transdisciplinary approach of analysis within the nexus boundaries and we analyse their implications. Our analysis contributes to the current debate on how to shape global and local responses to climate change by reflecting on lessons learnt and best practice from cross-stakeholder and cross-sectorial engagement. In so doing, it helps inform a new generation of complex systems models to analyse climate change impact on the food-water-energy Nexus

    Manufacturing Barriers to Biologics Competition and Innovation

    Get PDF
    As finding breakthrough small-molecule drugs gets harder, drug companies are increasingly turning to “large molecule” biologics. Although biologics represent many of the most promising new therapies for previously intractable diseases, they are extremely expensive. Moreover, the pathway for generic-type competition set up by Congress in 2010 is unlikely to yield significant cost savings. In this Article, we provide a fresh diagnosis of, and prescription for, this major public policy problem. We argue that the key cause is pervasive trade secrecy in the complex area of biologics manufacturing. Under the current regime, this trade secrecy, combined with certain features of FDA regulation, not only creates high barriers to entry of indefinite duration but also undermines efforts to advance fundamental knowledge. In sharp contrast, offering incentives for information disclosure to originator manufacturers would leverage the existing interaction of trade secrecy and the regulatory state in a positive direction. Although trade secrecy, particularly in complex areas like biologics manufacturing, often involves tacit knowledge that is difficult to codify and thus transfer, in this case regulatory requirements that originator manufacturers submit manufacturing details have already codified the relevant tacit knowledge. Incentivizing disclosure of these regulatory submissions would not only spur competition but it would provide a rich source of information upon which additional research, including fundamental research into the science of manufacturing, could build. In addition to provide fresh diagnosis and prescription in the specific area of biologics, the Article contributes to more general scholarship on trade secrecy and tacit knowledge. Prior scholarship has neglected the extent to which regulation can turn tacit knowledge not only into codified knowledge but into precisely the type of codified knowledge that is most likely to be useful and accurate. The Article also draws a link to the literature on adaptive regulation, arguing that greater regulatory flexibility is necessary and that more fundamental knowledge should spur flexibility. A vastly shortened version of the central argument that manufacturing trade secrecy hampers biosimilar development was published at 348 Science 188 (2015), available online

    Remote sensing/global change. A special bibliography

    Get PDF
    The first portion of this bibliography contains citations (with abstracts, when available) to unclassified literature contained in the NASA STI Database. These citations also appeared in issues of the abstract journal 'Scientific and Technical Aerospace Reports (STAR)', or in other announcement products offered by the NASA STI Program. The citations appear in ascending accession number order. A second section provides several indexes to the citations. They are subject term, personal author, report number, and accession number. The citations are included for the following disciplines as they relate to remote sensing and global change: astronautics, engineering, geosciences, life sciences, mathematical and computer sciences, social sciences, and space sciences

    Coping with the fallout for preference-receiving countries from EU sugar reform.

    Get PDF
    Developing countries can produce sugar at much lower cost than in the EU, yet reform of the EU sugar policy will result in both winners and losers among them. This is because the EU is both an exporter and importer of sugar. Sugar policy reform will mean a reduction in EU sugar production, benefiting competitive sugar exporters such as Brazil. But sugar policy reform will adversely affect those developing countries which currently benefit from preferential import access to the EU’s high-priced sugar market, while diminishing the benefits of those least developed countries to which duty-free and quota-free access has been promised after July 2009. This paper concentrates on the latter group of preference-receiving countries. It identifies the countries concerned and the extent of their potential losses. It critiques alternative proposals which have been put forward to assist these countries to adjust to the adverse effects of EU sugar policy reform. The paper concludes by proposing a modified package of measures to offset the negative effects of EU sugar policy reform on preference-receiving countries.EU sugar policy, preference erosion, compensation

    Clark v. Cry Baby Foods, LLC Agency\u27s Record v. 3 Dckt. 40016

    Get PDF
    https://digitalcommons.law.uidaho.edu/idaho_supreme_court_record_briefs/1755/thumbnail.jp

    Technology for large space systems: A bibliography with indexes (supplement 07)

    Get PDF
    This bibliography lists 366 reports, articles and other documents introduced into the NASA scientific and technical information system between January 1, 1982 and June 30, 1982. Subject matter is grouped according to systems, interactive analysis and design, structural concepts, control systems, electronics, advanced materials, assembly concepts, propulsion, solar power satellite systems, and flight experiments

    Reform of the Fiscal and Subsidy Regime for the Petroleum Sector (Based on a Report Commissioned by the Petroleum Federation of India)

    Get PDF
    Reform of the oil sector is long overdue. The problems in the sector emanate from the structure of central taxes and the system of subsidisation through prices. Solutions to the problems necessarily have to address both tax and subsidy simultaneously. The social losses include, misuse / wasteful use of scarce petroleum resources, diversion, adulteration, other avoidable negative externalities, improper substitution between products, tax arbitrage, distortion of consumer preferences and input choices of industries, and international cross hauling of petroleum. Nearly all these costs, and problems arise not because of subsidisation per se but due to the use of varying retail prices that are used to subsidise. Prices for the same product vary for different consumers besides. They also vary across products. These tax /subsidy variations are the root cause of nearly all problems in the sector. Autonomous price variations (i.e. those resulting from the actions of firms (under a regime of non-distortionary subsidies) would be small and not subject to ‘arbitrage’ i.e. to the realisation of rents through diversion and adulteration. Tax reform – viz casting all taxes in the form of value added taxes has not taken place in the sector despite the passage of nearly 15 years since such reform was put in place in nearly all other sectors of manufacturing. Complete deregulation of the sector allowing oil producers, oil refiners, marketing companies, and integrated operators to price their products as they deem fit. Recast central indirect taxes (excise whether specific or ad valorem) into a value added tax, as for any other product., i.e., allowing input credit for all registered intermediate users of petroleum products is overdue. Central government revenues can be protected by working out a revenue neutral value added tax rate. This we have estimated approximately to be 110-120% of value added uniformly to all segments in the industry. Such a tax regime would also be neutral to the degree of vertical integration and remove the biases in the use of products. The Public Distribution System (PDS) is not necessary and ought to be dismantled. Kerosene would then be sold in the open market for all consumers. Kerosene could also be sold by retail outlets, kirana shops, other retail outlets, and by current PDS retailers on par with kirana shops/ ROs. Ditto for LPG. Subsidies are administered through endowments defined upfront, which allows the subsidised consumer to access his/her endowments, trade the same, convert the same into cash all without the causing any distortion. Only pipelines are subject to regulation by the Petroleum and Natural Gas Regulator. The second best proposals involve the changes/recommendations as before but additionally creates a “Crude Price Stabilisation Fund” (CSF) that allows crude prices (both sharp rises and sudden falls) to be moderated, so that pass thru is influenced by the managers of the CSF. It is important that the CSF is set up as in independent body and insulated from the government and is governed by strict and automatic rules that make rapid price adjustment (to the market prices) necessary when the fund position is low, so that the probability of the fund going bankrupt is kept at nearly zero. A fund between 25to40billionisenvisaged.Afundof 25 to 40 billion is envisaged. A fund of 40 billion (Rs. 200,000 crore) envisaged as a credit line would work in most situations. The fund would operate with strict limits on the quantum of the credit line used to pay out stabilization subsidies during the boom phase of the price cycle as also on the accumulated reserves built up from stabilization taxes during the bust phase of the price cycle. To ensure that such crude stabilisation measures do not affect the competitiveness of the industry exports of product (and crude) are taxed when crude is subsidised, and subsidised when crude is taxed. Appropriate conversion factors would apply. The conversion factor should be based on a refinery loss of between 10 and 7% say 8.5%.

    Nonprofit Social Enterprise: Social Change in a New Economic Paradigm

    Get PDF
    Changes are afoot in the nonprofit sector of the economy (James, 2003). Nonprofit leaders are adopting entrepreneurial business models to sustain or expand the scope of their mission work. This change is part of a counter-hegemonic shift toward a new economic paradigm in which blended business models create both social and financial value (Sabeti, 2009; Sahakian & Dunand, 2013). The current study explored how nonprofit leaders understand the shift toward a more enterprising and entrepreneurial nonprofit sector. Qualitative methods, along with a grounded theory framework were used to elicit leaders\u27 perspectives on the emergence of social enterprise in nonprofits and the characteristics of successful nonprofit social enterprise. Findings include five themes of social enterprise understanding that offer structure for further research and professional discourse on the subject, including: 1) Social enterprise as a necessary and inevitable evolution of the nonprofit organization; 2) Social enterprise as a means of achieving a social mission; 3) Social enterprise as a true blending of business and social impact models; 4) Social enterprise as a business principle applied to a social mission context; and 5) Social enterprise as a market-driven approach to financial and social value creation. A secondary analysis points to the emergence of a social enterprise synergy effect in which the social and financial value generated by nonprofit social enterprises yield a third effect that is greater than the sum of the individual parts. The implications of these findings are limited to nonprofit social enterprises, but contribute to our understanding of this nascent field
    corecore