1,046 research outputs found

    Late consequences of early selection: when memory monitoring backfires

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    At retrieval, people can adopt a retrieval orientation by which they recreate the mental operations used at encoding. Monitoring by retrieval orientation leads to assessing all test items for qualities related to the encoding task, which enriches foils with some of the qualities already possessed by targets. We investigated the consequences of adopting a retrieval orientation under conditions of repeated monitoring of the same foils. Participants first processed foils in the context of one of two tests encouraging different retrieval orientations. The foils were then re-used on a subsequent test in which retrieval orientation either matched or mismatched that adopted on the first test. In the aggregate data, false alarms for repeated foils were higher when there was a match between the retrieval orientations on both tests. This demonstrates that when retrieval orientation enriches foils with target-like characteristics, it can backfire when repeated monitoring of the same foils is required

    Late consequences of dental injuries

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    U radu su opisane kasne posljedice traumatiziranih zuba koji nisu bili endodontološki liječeni nakon ozljede pulpe.Cases of late consequences of traumatized teeth without endodontic treatment performed after the injury are presented and discussed

    Late consequences of knee injury.

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    Tato bakalářská práce se zabývá problematikou úrazů kolenního kloubu a gonartrózy. Práce má teoreticko-empirický charakter. Teoretická část je rozdělená do tří hlavních kapitol. V první kapitole je popsána anatomie kolenního kloubu. Druhá kapitola se věnuje úrazům, je zaměřena na poranění vazivového aparátu, menisků, chrupavky a úrazy pately. V poslední kapitole je zpracována gonartróza, její etiologie, projevy, léčba a prevence. Empirická část obsahuje výsledky výzkumu. Výzkumné šetření proběhlo formou anonymního dotazníku. Respondenty byly osoby starší 18 let po úrazu kolenního kloubu. Zkoumaný vzorek tvořilo 102 respondentů. Cílem empirické části bylo zjistit, s jakým úrazem mají respondenti zkušenost, jak se staví k doléčování úrazů, jaké mají znalosti o gonartróze a jestli se věnují prevenci. Výsledky byly zpracovány do tabulek a grafů. Z výzkumného šetření vyplývá, že nejčastějším zraněním je poranění předního zkříženého vazu. Třetina respondentů po úrazu nedodržuje léčebný režim, nejčastěji nedodrží chůzi o berlích či nošení ortézy. Více jak 80% zná příznaky gonartrózy, stádia artrózy zná 11,76% respondentů. Prevenci se věnuje 53,92% respondentů. Klíčová slova: kolenní kloub, úraz kolenního kloubu, poranění měkkého kolena, gonartróza, prevenceThis thesis deals with the issue of knee injuries and gonarthrosis. The thesis has theoretical and empirical character. The theoretical section is divided into three main chapters. The anatomy of the knee joint is described in the first chapter. Second chapter deals with knee injuries; this part is focused on the injuries to ligaments, menisci, cartilage and patella. Gonarthrosis, its etiology, symptoms, treatment and prevention, is compiled in the last chapter. The empirical section contains the results of research. The research was performed as an anonymous questionnaire study. Respondents were older than 18 years and after the knee injury. The sample consisted of 102 respondents. The aim of the empirical section was to find out what kind of injuries the clients have experienced, their attitude towards the after-treatment of the injuries, their knowledge of gonarthrosis and whether they occupy themselves with its prevention. The results were processed into charts and graphs. The research show, that the most common injury is one to the anterior cruciate ligament. A third of the respondents does not follow the treatment regimen, most frequently they fail to walk on crutches or to wear a knee brace. More than 80% of respondents know the symptoms, but only 11,76% of respondents know stages of...Institute of Theory and Practice of Nursing First Faculty of Medicine Charles University in PragueÚstav teorie a praxe ošetřovatelství 1. LF UK v PrazeFirst Faculty of Medicine1. lékařská fakult

    PMH2 EVIDENCE FOR SSRI IN THE TREATMENT OF DEPRESSION: EARLY KNOWLEDGE GAIN—LATE CONSEQUENCES IN ROUTINE CARE?

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    Recurrent second-trimester intrauterine fetal death due to undiagnosed atrioventricular block: A case report

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    Fetal cardiac abnormalities are one of the common causes of non-immune fetal hydrops. Early diagnosis and treatment may prevent the late consequences that can occur as heart failure and intrauterine fetal death. Herein we report the case of a 32-year-old patient with a history of recurrent second trimester intrauterine fetal death. She presented with fetal hydrops at 23 weeks. A detailed echocardiography revealed that the fetus had a third degree atrioventricular block and advanced hydropic changes due to heart failure. Corticosteroid therapy was started but the fetus died in utero after 2 weeks

    Imaging in Minor Head Injury: Early complications and late consequences

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    Head injury is traditionally divided into minor, moderate or severe head injury, depending on the patient’s presenting level of consciousness as expressed in the Glasgow Coma Scale (GCS) score. Th e vast majority of patients (>90%) present with a normal or nearnormal level of consciousness (GSC score of 13–15) and are thus classifi ed as minor head injury patients (1, 2). With an estimated 60 000 patients annually in the Netherlands, minor head injury forms a major health care and societal burden. Despite being classifi ed as ‘minor’, the injury is not inconsequential. Consequences of minor head injury can be divided into early, potentially lifethreatening complications, and long-term functional disability as well as a wide range of postconcussive complaints

    Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease

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    Disturbances in the sleep–wake cycle and circadian rhythms are common symptoms of Alzheimer Disease (AD), and they have generally been considered as late consequences of the neurodegenerative processes. Recent evidence demonstrates that sleep–wake and circadian disruption often occur early in the course of the disease and may even precede the development of cognitive symptoms. Furthermore, the sleep–wake cycle appears to regulate levels of the pathogenic amyloid-beta peptide in the brain, and manipulating sleep can influence AD-related pathology in mouse models via multiple mechanisms. Finally, the circadian clock system, which controls the sleep–wake cycle and other diurnal oscillations in mice and humans, may also have a role in the neurodegenerative process. In this review, we examine the current literature related to the mechanisms by which sleep and circadian rhythms might impact AD pathogenesis, and we discuss potential therapeutic strategies targeting these systems for the prevention of AD

    Malignant disease in childhood : the price of cure : late physical and socioeconomic effects of treatment

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    The aim of cancer therapy in childhood is to achieve a lasting cure without physical and psychosocial harm and, preferably, at a low financial cost. Although cure is possible in many types of childhood cancer, this is often accompanied by complications as a consequence of intensive therapy. These late effects primarily affect fertility, the cardio-respiratory and endocrinological systems. Psychosocial adverse effects may have serious implications on the marriage and employment prospects of those patients surviving into adulthood. Furthermore, the risk of treatment-induced, secondary malignancies may increase as survival improves. With current intensive chemotherapy and radiotherapy, the attainment of cure rates in (EXC)ess of 60-70% is, inevitably, associated with significant morbidity. Indeed, recent developments in cancer therapy have focused on ways of reducing this morbidity, whilst still maintaining the overall improvement in survival.peer-reviewe

    Long-term health outcomes after exposure to repeated concussion in elite level: rugby union players

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    Background: There is continuing concern about effects of concussion in athletes, including risk of the neurodegenerative disease chronic traumatic encephalopathy. However, information on long-term health and wellbeing in former athletes is limited. Method: Outcome after exposure to repeated brain injury was investigated in 52 retired male Scottish international rugby players (RIRP) and 29 male controls who were similar in age and social deprivation. Assessment included history of playing rugby and traumatic brain injury, general and mental health, life stress, concussion symptoms, cognitive function, disability and markers of chronic stress (allostatic load). Results: The estimated number of concussions in RIRP averaged 14 (median=7; IQR 5-40). Performance was poorer in RIRP than controls on a test of verbal learning (p=0.022) and of fine co-ordination of the dominant hand (p=0.038) and not significantly different on other cognitive tests (p>0.05). There were no significant associations between number of concussions and performance on cognitive tests. Other than a higher incidence of cardiovascular disease in controls, no group differences were detected in general or mental health or estimates of allostatic load. In RIRP, persisting symptoms attributed to concussion were more common if reporting more than nine concussions (p=0.028), although these symptoms were not perceived to affect social or work functioning. Conclusions: Despite a high number of concussions in RIRP, differences in mental health, social or work functioning were not found late after injury. Subtle group differences were detected on two cognitive tests, the cause of which is uncertain. Prospective group comparison studies on representative cohorts are required
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