Importance of Sleep

My topic is importance of sleep. As college students, our sleeping routine is not being emphasized a lot and most college students spend their nights either doing homework, having an all-nighter, going out and so on. we tend to face the effect of not having a good night sleep the following day. People tend to get drained, irritable and sleepy all day and wonder why this is happening. it the effects of having less than eight hours of sleep. I choose this topic to bring more light and emphasis on having a good, health sleep routine.https://digitalcommons.cortland.edu/corslides/1005/thumbnail.jp

Memory processing: the critical role of neuronal replay during sleep

Patterns of neuronal activity present during learning in the hippocampus are replayed during sleep. A new study highlights the functional importance of this neurophysiological phenomenon by showing that neuronal replay is critical for memory processing over a night of sleep

Emotional Effects of the Duration, Efficiency, and Subjective Quality of Sleep in Healthcare Personnel

Considering that both sleep quality and duration are linked to psychological variables, this study analyzed the relationships between sleep components and emotional intelligence and the effects that sleep duration has on stress management and mood in a sample of nurses. The sample was made up of 1073 professionals. Data were collected by the Pittsburgh Sleep Quality Index and the Brief Emotional Intelligence Inventory for Senior Citizens. The results showed that the components of sleep quality were negatively related to stress management and mood. Furthermore, nurses who had short sleep patterns also had low moods and high stress levels. This study emphasizes the importance of subjective sleep quality as a necessary resource for professionals to manage stressful situations and mood and improve their relations with their patients and with each other

Clinician perceptions of sleep problems, and their treatment, in patients with non-affective psychosis

Aims and method: To assess clinicians’ views about their understanding and treatment of sleep problems in people with non-affective psychosis. An online survey was emailed to adult mental health teams in two NHS trusts. Results: One hundred and eleven clinicians completed the survey. All clinicians reported disrupted sleep in their patients, and endorsed the view that sleep and psychotic experiences each exacerbate the other. However, most clinicians (n = 92, 82%) assessed sleep problems informally, rather than using standard assessment measures. There was infrequent use of the recommended cognitive-behavioural treatments for sleep problems such as persistent insomnia, with the approaches typically used being sleep hygiene and medications instead. Clinical implications: Clinicians recognise the importance of sleep in psychosis, but the use of formal assessments and recommended treatments is limited. Barriers to treatment implementation identified by the clinicians related to services (e.g. lack of time), patients (e.g. their lifestyle) and environmental features of inpatient settings

Do sleep difficulties exacerbate deficits in sustained attention following traumatic brain injury?

Sustained attention has been shown to be vulnerable following traumatic brain injury (TBI). Sleep restriction and disturbances have been shown to negatively affect sustained attention. Sleep disorders are common but under-diagnosed after TBI. Thus, it seems possible that sleep disturbances may exacerbate neuropsychological deficits for a proportion of individuals who have sustained a TBI. The aim of this prospective study was to examine whether poor sleepers post-TBI had poorer sustained and general attentional functioning than good sleepers post-TBI. Retrospective subjective, prospective subjective, and objective measures were used to assess participants’ sleep. The results showed that the poor sleep group had significantly poorer sustained attention ability than the good sleep group. The differences on other measures of attention were not significant. This study supports the use of measures that capture specific components of attention rather than global measures of attention, and highlights the importance of assessing and treating sleep problems in brain injury rehabilitation

Sleep: A Human Rights Issue

Recognition of sleep as a human rights issue by governmental and legal entities (as illustrated by recent legal cases in the United States and India) raises the profile of sleep health as a societal concern. Although this recognition may not lead to immediate public policy changes, it infuses the public discourse about the importance of sleep health with loftier ideals about what it means to be human. Such recognition also elevates the work of sleep researchers and practitioners from serving the altruistic purpose of improving human health at the individual and population levels to serving the higher altruistic purpose of promoting human rights for all people. These conditions create an environment in which policy change that values individual and population sleep health can occur gradually over time, particularly in societies with strong democratic traditions

Altered sleep and EEG power in the P301S Tau transgenic mouse model

OBJECTIVE: Sleep disturbances are prevalent in human tauopathies yet despite the importance of sleep, little is known about its relationship with tau pathology. Here, we investigate this interaction by analyzing sleep and tau pathology throughout tauopathy disease progression in P301S human tau transgenic mice. METHODS: P301S and wild‐type mice were analyzed by electroencephalography (EEG)/electromyography at 3, 6, 9, and 11 months of age for sleep/wake time, EEG power, and homeostatic response. Cortical volume and tau pathology was also assessed by anti‐phospho‐tau AT8 staining. RESULTS: P301S tau mice had significantly decreased rapid eye movement (REM) sleep at 9 months of age and decreased REM and non‐REM (NREM) sleep as well as increased wakefulness at 11 months. Sleep loss was characterized by fewer wake, REM, and NREM bouts, increased wake bout duration, and decreased sleep bout duration. Decreased REM and NREM sleep was associated with increased brainstem tau pathology in the sublaterodorsal area and parafacial zone, respectively. P301S mice also showed increased EEG power at 6 and 9 months of age and decreased power at 11 months. Decreased EEG power was associated with decreased cortical volume. Despite sleep disturbances, P301S mice maintained homeostatic response to sleep deprivation. INTERPRETATION: Our results indicate that tau pathology is associated with sleep disturbances that worsen with age and these changes may be related to tau pathology in brainstem sleep regulating regions as well as neurodegeneration. Tau‐induced sleep changes could affect disease progression and be a marker for therapeutic efficacy in this and other tauopathy models

The Importance of Sleep

Many people nowadays struggle with sleep. Research has shown that 22% of people struggle with sleepand out of those, 66% have a sleep disorder. This shows how complicated the sleep process is for the vast majority of people. My research was organized in many stages, first I wrote down what I already knew about sleep (which was nothing compared to the amount of things I found after my research). Secondly, I started looking at a lot of research projects led by the best scientists and organizations about sleep. I found that sleep is divided into many sections and what happens in each one of those, the important role that HRV and the Circadian rhythm play in the sleep process, irregular sleep leads to poor performance and that the key of good sleep is consistency. With all this information I could see why many people including me struggle so much with sleep. After doing the research I put into practice all the things I learned from doing this research and my life has changed for the better. This impacted my life in a very positive way

Genome-wide screen for genes involved in Caenorhabditis elegans developmentally timed sleep

In Caenorhabditis elegans, Notch signaling regulates developmentally timed sleep during the transition from L4 larval stage to adulthood (L4/A) . To identify core sleep pathways and to find genes acting downstream of Notch signaling, we undertook the first genome-wide, classical genetic screen focused on C. elegans developmentally timed sleep. To increase screen efficiency, we first looked for mutations that suppressed inappropriate anachronistic sleep in adult hsp::osm-11 animals overexpressing the Notch coligand OSM-11 after heat shock. We retained suppressor lines that also had defects in L4/A developmentally timed sleep, without heat shock overexpression of the Notch coligand. Sixteen suppressor lines with defects in developmentally timed sleep were identified. One line carried a new allele of goa-1; loss of GOA-1 Gαo decreased C. elegans sleep. Another line carried a new allele of gpb-2, encoding a Gβ5 protein; Gβ5 proteins have not been previously implicated in sleep. In other scenarios, Gβ5 GPB-2 acts with regulators of G protein signaling (RGS proteins) EAT-16 and EGL-10 to terminate either EGL-30 Gαq signaling or GOA-1 Gαo signaling, respectively. We found that loss of Gβ5 GPB-2 or RGS EAT-16 decreased L4/A sleep. By contrast, EGL-10 loss had no impact. Instead, loss of RGS-1 and RGS-2 increased sleep. Combined, our results suggest that, in the context of L4/A sleep, GPB-2 predominantly acts with EAT-16 RGS to inhibit EGL-30 Gαq signaling. These results confirm the importance of G protein signaling in sleep and demonstrate that these core sleep pathways function genetically downstream of the Notch signaling events promoting sleep

Sleep Disturbances and Fatigue in Adolescents with Cancer Receiving Chemotherapy

Sleep disturbances and fatigue are frequently complained by adolescents with cancer. These problems will lead to a variety of changes that may affect adolescents’ development. However, there is very limited data concerning adolescents with cancer in Indonesia. The research aims to explore sleep disturbances and fatigue in adolescents with cancer who are receiving chemotherapy. The research applies a qualitative design with phenomenology approach. Data were collected using in-depth interviews with seven adolescents with cancer in Jakarta, Bogor, and Bekasi. The interviews involved open questions on seven aspects, consisting of level of fatigue, responses to psychological drives, sleep disturbances, sleep disruption due to illness and chemotherapy, disruptions in some aspects of daily life, responses to problematic situations, and general perspective on life. Participants stated that chemotherapy induced sleep disturbances and fatigue, and this situation greatly influenced their overall quality of life. These problems are interrelated to each other and may affect the success of chemotherapy program. In terms of nursing, this research also shows the importance of developing a more effective system for managing sleep disturbances and fatigue during chemotherapy program