Phosphoproteins associated with cyclic nucleotide stimulation of ciliary motility in Paramecium

Permeabilized, MgATP-reactivated cells of Paramecium (models) respond to cyclic AMP and cyclic GMP by increasing forward swimming speed. In association with the motile response, cyclic AMP and 8-bromo-cyclic GMP (8-Br-cyclic GMP) stimulated protein phosphorylation. Cyclic AMP addition to permeabilized cells reproducibly stimulated the phosphorylation of 10 proteins, ranging in molecular weight from 15 to 110K (K = 10^3 M_r). 8-Br-cyclic GMP, which selectively activates the cyclic GMP-dependent protein kinase of Paramecium, stimulated the phosphorylation of a subset of the proteins phosphorylated by cyclic AMP. Ca^(2+) addition caused backward swimming and stimulated the phosphorylation of four substrates, including a 25K target that may also be phosphorylated in response to cyclic nucleotide addition. Ba^(2+) and Sr^(2+) also induced backward swimming, but did not cause detectable phosphorylation. To identify ciliary targets of cyclic nucleotide-dependent protein kinase activity, permeabilized cells were deciliated following reactivation of motility with Mg-[y-^(32)P]ATP in the presence or absence of cyclic nucleotide. Soluble proteins of the deciliation supernatant were enriched in 15 cyclic AMP-stimulated phosphoproteins, ranging in molecular weight from 15 to 95K. Most of the ciliary substrates were axonemal and could be released by high salt solution. A 29K protein that copurified in sucrose gradients with the 22S dynein, and a high molecular weight protein (greater than 300K) in the 19 S region were phosphorylated when cyclic AMP was added to permeabilized, motile cells. These data suggest that regulation of ciliary motility by cyclic AMP may include phosphorylation of dynein-associated proteins

Quasi-cyclic subcodes of cyclic codes

We completely characterize possible indices of quasi-cyclic subcodes in a cyclic code for a very broad class of cyclic codes. We present enumeration results for quasi-cyclic subcodes of a fixed index and show that the problem of enumeration is equivalent to enumeration of certain vector subspaces in finite fields. In particular, we present enumeration results for quasi-cyclic subcodes of the simplex code and duals of certain BCH codes. Our results are based on the trace representation of cyclic codes

Cyclic networks of quantum gates

In this article initial steps in an analysis of cyclic networks of quantum logic gates is given. Cyclic networks are those in which the qubit lines are loops. Here we have studied one and two qubit systems plus two qubit cyclic systems connected to another qubit on an acyclic line. The analysis includes the group classification of networks and studies of the dynamics of the qubits in the cyclic network and of the perturbation effects of an acyclic qubit acting on a cyclic network. This is followed by a discussion of quantum algorithms and quantum information processing with cyclic networks of quantum gates, and a novel implementation of a cyclic network quantum memory. Quantum sensors via cyclic networks are also discussed.Comment: 14 pages including 11 figures, References adde