Additional file 1 of Novel PAK3 gene missense variant associated with two Chinese siblings with intellectual disability: a case report

Additional file 1 Table S1. Stability results of PAK3 and variant, produced by Molecular Operating Environment (MOE). Table S2. The summary of variants consistent with the inheritance model other than the PAK3 gene in this family from the trio-WES data

Additional file 1 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

Additional file 1. Manually curated CFTR variants’ pathogenicity

MOESM1 of Clarithromycin synergizes with cisplatin to inhibit ovarian cancer growth in vitro and in vivo

Additional file 1 Table S1. Primers used in this study for real-time PCR experiments. (DOC 38 kb

Additional file 2 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

Additional file 2. Containing supplementary figures 1–6, supplementary table 3, supplementary table 4, and supplementary notes

Opening Magnesium Storage Capability of Two-Dimensional MXene by Intercalation of Cationic Surfactant

Two-dimensional (2D) Ti₃C₂ MXene has attracted great attention in electrochemical energy storage devices (supercapacitors and lithium-ion and sodium-ion batteries) due to its excellent electrical conductivity as well as high volumetric capacity. Nevertheless, a previous study showed that multivalent Mg²⁺ ions cannot reversibly insert into MXene, resulting in a negligible capacity. Here, we demonstrate a simple strategy to achieve high magnesium storage capability for Ti₃C₂ MXene by preintercalating a cationic surfactant, cetyltrimethylammonium bromide (CTAB). Density functional theory simulations verify that intercalated CTA⁺ cations reduce the diffusion barrier of Mg²⁺ on the MXene surface, resulting in the significant improvement of the reversible insertion/deinsertion of Mg²⁺ ions between MXene layers. Consequently, the MXene electrode exhibits a desirable volumetric specific capacity of 300 mAh cm^–3 at 50 mA g^–1 as well as outstanding rate performance. This work endows MXene material with an application in electrochemical energy storage and, simultaneously, introduces magnesium battery materials as a member

Additional file 1: of Identification of genetic factors underlying persistent pulmonary hypertension of newborns in a cohort of Chinese neonates

Table S1 Reported PAH/PPHN related genes. (DOCX 18 kb

Additional file 4 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

Additional file 4. Designed capture regions of CES and WES on CFTR gene

Additional file 3 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

Additional file 3. Collected variants list of Caucasian-specific CF screening panels

MOESM2 of Clarithromycin synergizes with cisplatin to inhibit ovarian cancer growth in vitro and in vivo

Additional file 2. The IHC score of each gene is calculated as described in materials and methods (Fig. A,B,C and D). (TIF 461 kb

Additional file 1 of Comprehensive assessment of the genetic characteristics of small for gestational age newborns in NICU: from diagnosis of genetic disorders to prediction of prognosis

Additional file 1: Additional method. The inclusion criteria of the China Neonatal Genomes Project (CNGP). Table S1. Uniparental disomy (UPD) types and disease associated with growth failure. Table S2. The matching results of cases and controls for gestational age, sex, and whether the pregnant mother had gestational hypertension by matching (PSM). Table S3. Characteristics of SGA newborns with different genetic diagnosis. Table S4. The OMIM diseases and detailed developmental phenotypes for SGA-related genes. Table S5. The OMIM diseases and the relevance of disease to underdevelopmental abnormalities for non SGA-related genes. Table S6. The OMIM diseases and multiple organs or systems involved for syndromic genes. Table S7. Monogenetic variants result. Table S8. Characteristics of SGA newborns with different monogenic variants results. Table S9. Chromosomal abnormalities result. Table S10. The risk genes identified based on the gene burden test. Table S11. The baseline information of the SGA-model generation dataset and the SGA-validation dataset