96 research outputs found
Volatility modelling on the use of structural breaks
This thesis focuses on examining potential impacts that structural breaks impose on volatility modelling via GARCH models. After incorporating structural breaks detected by the modified ICSS of Sanso et al. (2004) into conventional GARCH models, reduced volatility persistence is obtained for stock and foreign exchange returns in both China and the UK. A unidirectional volatility spillover is found going from stock to foreign exchange market for both countries, and ignoring structural breaks can lead to biased spillover patterns. These findings are well supported by comprehensive Monte Carlo simulations
Volatility modelling on the use of structural breaks
This thesis focuses on examining potential impacts that structural breaks impose on volatility modelling via GARCH models. After incorporating structural breaks detected by the modified ICSS of Sanso et al. (2004) into conventional GARCH models, reduced volatility persistence is obtained for stock and foreign exchange returns in both China and the UK. A unidirectional volatility spillover is found going from stock to foreign exchange market for both countries, and ignoring structural breaks can lead to biased spillover patterns. These findings are well supported by comprehensive Monte Carlo simulations
Table_1_Mobile-assisted vocabulary learning through the Shanbay App outside the classroom: Effects of self-regulation and peer scaffolding.DOCX
Recent decades have witnessed an increasing academic interest in mobile-assisted vocabulary learning. To explore the possible influencing factors on learning outcomes, this study aimed at examining the effects of self-regulation and peer scaffolding on mobile-assisted vocabulary learning among undergraduate students using Shanbay App beyond the classroom. To this end, altogether 71 intermediate-level English learners aged 17–19 years were chosen as participants, with 37 in the experimental group (with peer scaffolding) and 34 in the control group (without peer scaffolding). Data were collected through the Shanbay App regarding participants’ vocabulary learning performance, a self-regulation questionnaire and semi-structured interviews. The results of factorial ANOVA revealed that peer scaffolding significantly affected mobile vocabulary learning in terms of the days spent in vocabulary learning and the sum of words participants have learned; a main effect of self-regulation and an interaction effect of self-regulation and peer scaffolding were also observed on the sum of learned words. The research is innovative in providing a motivational peer scaffolding framework in mobile vocabulary learning settings, and may provide pedagogical implications for vocabulary teaching in EFL context in higher education.</p
Data_Sheet_1_Relationship between subjective well-being and depressive disorders: Novel findings of cohort variations and demographic heterogeneities.docx
This paper uses a large-scale nationally representative dataset, the Chinese General Social Survey, to examine the relationship between subjective well-being and depressive disorders. Statistical results indicate that higher levels of subjective well-being help decrease perceived depression. Robustness checks are carried out using different types of explanatory and dependent variables, various regression models, penalized machine learning methods, instrumental variable approaches, and placebo tests, all of which lend further credence to the above findings. Based on it, heterogeneities in the relationship between subjective well-being and self-rated mental disorders are explored. In respect of variations in age cohorts, it is found that the absolute values of happiness’s estimated coefficients are smaller in the 20–30 and 30–40 age groups, while that in the 40–50 age group increase substantially. In older cohorts, the estimates remain at higher levels while fluctuating to some degree. Furthermore, the significantly negative interaction between happiness and age proves that age amplifies subjective well-being’s effect on perceived depressive disorders. With age increasing, the impact of happiness on reducing perceived depression tends to be stronger. Therefore, for older people, subjective well-being plays a more important role in suppressing self-rated depression. Heterogeneities of the relationship between happiness and perceived depressive disorders in subgroups with different demographic characteristics are also investigated. It is found that the negative correlation between subjective well-being and self-rated depression is stronger among those with higher educational levels, living in urban areas, being members of the Communist Party of China, having pensions, and owning more housing assets. However, gender, ethnic identity, religious belief, and marital status exert no significant moderating effects.</p
Correction to “Biomimetic Total Synthesis of Paeoveitol”
Correction to “Biomimetic Total Synthesis of
Paeoveitol
Additional file 1 of Efficacy of pharmacotherapies for bulimia nervosa: a systematic review and meta-analysis
Additional file 1: Supplementary Fig. S1 Forest plot of wight change. Supplementary Fig. S2 Forest plot of depression scores. Supplementary Fig. S3 Forest plot of dropouts due to adverse events. Supplementary Fig. S4 Forest plot of binge-eating episodes (10 weeks as the boundary). Supplementary Fig. S5 Forest plot of vomiting episodes (10 weeks as the boundary)
Biomimetic Total Synthesis of Paeoveitol
A highly
stereocontrolled
synthesis of paeoveitol has been developed in 26% yield, in 7 steps
from commercially available materials. The synthetic strategy was
inspired primarily by the biogenetic hypothesis and was enabled by
hetero-Diels–Alder cycloaddition to construct the target molecular
framework
Repolarization of Inflammation-Associated Macrophages by Dual Drug-Loaded Liposomes for Acute Lung Sepsis Antibacterial and Anti-inflammatory Therapy
Sepsis is defined as a systemic inflammatory response
syndrome
caused by a dysregulated host response to bacterial infection and
is the leading cause of death in the intensive care unit at hospitals.
At present, despite the discovery of many potential therapeutic methods
for anti-infective treatment and immune-suppressing treatment, effective
drug treatments for sepsis are lacking in the clinic. Herein, a coloaded
dual therapeutic agent liposome (Cip·HCl/Cur@Lip-γ3) nanoplatform
was developed by enveloping Cip·HCl and Cur into pH-responsive
and inflammation-targeted liposomes. These liposomes simultaneously
kill bacteria and regulate the polarization types of macrophages in
infected lung tissue to relieve the infected microenvironment, providing
antibacterial–anti-inflammatory therapy for synergetic acute
lung sepsis. In vitro and in vivo results showed that Cip·HCl/Cur@Lip-γ3
exhibits excellent antibacterial properties against both Staphylococcus aureus and Pseudomonas
aeruginosa and can effectively reduce inflammation
and the immune response in acute lung infection. In addition, Cip·HCl/Cur@Lip-γ3
was administered to mice with acute lung infection, and the survival
rate was 80% within 72 h. This study provides a nanoplatform to treat
lung infection-induced sepsis, providing a strategy to design multifunctional
nanomedicine for infectious disease therapy
Biomimetic Syntheses of Callistrilones A–E via an Oxidative [3 + 2] Cycloaddition
Concise
total syntheses of callistrilones A–E have been
achieved from <b>7</b> and commercially available α-phellandrene
(<b>8</b>). The synthetic strategy, which was primarily inspired
by the biogenetic hypothesis, was enabled by an oxidative [3 + 2]
cycloaddition followed by a Michael addition and an intramolecular
nucleophilic addition to construct the target molecules. Moreover,
viminalin I was also synthesized, and its absolute configuration was
unambiguously confirmed
Wood fiber aerogel-based super hydrophilic and lipophobic porous structure as a photothermal material for efficient solar steam
We demonstrate in this paper a super-hydrophilic and oleophobic green porous photothermal material based on wood fiber as a novel oil-repellent photothermal material for efficient solar vapor generation (WF-SP). WF-SP is an excellent light-absorbing material with the advantages of a porous nanostructure, super-hydrophilic, low thermal conductivity, high-temperature resistance, and oleophobicity. Based on these advantages, WF-SP exhibits good solar photothermal conversion performance with solar vapor generation efficiencies of 85.4%, 75.3%, and 70.2% at 1 kW m−2, 2 kW m−2, and 3 kW m−2 radiation intensities, respectively. The results provide new possibilities for the design and preparation of low-cost, green, and pollution-free photothermal materials with high solar thermal conversion efficiency for solar photothermal conversion vapor generation.</p
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