GC/MS and LC-MS/MS phytochemical evaluation of the essential oil and selected secondary metabolites of Ajuga orientalis from Jordan and its antioxidant activity

The current investigation aimed to shed light in the volatile and non-volatile secondary metabolites of Ajuga orientalis L. from Jordan. GC/MS and GC/FID analysis of the hydrodistilled essential oil obtained from aerial parts of the plant revealed tiglic acid (18.90 %) as main constituent. Each of the methanol and butanol fractions of A. orientalis were screened for their total phenol content (TPC), total flavonoid content (TFC), and antioxidant activity determined by DDPH and ABTS methods. The extracts were then analyzed by LC-ESI-MS/MS to unveil their chemical constituents, especially phenols and flavonoids. Results showed that the AO-B extract had the highest TPC (217.63 ± 2.65 mg gallic acid/g dry extract), TFC (944.41 ± 4.77 mg quercetin /g dry extract), highest DPPH and ABTS antioxidant activity ((4.00 ± 0.20) × 10-2; (3.00 ± 0.20) × 10-2 mg/mL, respectively) as compared to the AO-M extract. LC-ESI-MS/MS analysis of both extracts revealed the presence of several phenolics, flavonoids and nonphenolic acids

Ballota saxatilis from Jordan: Evaluation of Essential Oil Composition and Phytochemical Profiling of Crude Extracts and Their In-Vitro Antioxidant Activity

The chemical composition of essential oil extracted from the aerial parts of Ballota saxatilis Sieber ex C.Presl from Jordan has been elucidated by gas chromatography–mass spectrometry (GC-MS). Additionally, aqueous methanol (BsA), Butanol (BsB) and water (BsW) extracts were screened for their total phenol content (TPC), total flavonoid content (TFC), and antioxidant activities using the 2,2 Diphenyl-1-picrylhydrazyl (DPPH) and 2,2-Azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) diammonium salt (ABTS) methods. The most potent extracts were screened for their phenolic acids and flavonoid content using liquid the chromatography–mass spectrometry (LC-MS) technique. The results indicated that the essential oil predominantly contained cis-pinane (14.76%), β-caryophyllene (8.91%) and allo-aromadendrene epoxide (6.39%). Among the different extracts investigated, the BsB fraction had the most TPC and TFC (455.79 ± 1.03 µg gallic acid/g dry extract; 272.62 ± 8.28 µg quercetin/g dry extract, respectively) and had the best radical and radical cation scavenging activities, as determined using the DPPH and ABTS methods. Quantitative and qualitative LC-MS analyses of BsA and BsB using LC-MS revealed each of the kaempferol-3-O-rutinoside (30.29%), chrysoeriol-7-glucoside (7.93%) and luteolin 7-o-glucoside (7.76%) as the main constituents of the BsA fraction. The BsB fraction was rich in 7,4′-dimethoxy-3-hydroxyflavone (34.68%), kaempferol-3,7,4′-trimethyl ether (29.17%) and corymbosin (9.66%) and lower concentration levels of kaempferol-3-O-rutinoside (1.63%) and chrysoeriol-7-glucoside (0.51%)

Synthesis, Characterization of Poly(1,4–cyclohexanedimethylene oxalate) and the Study of its Metal Uptake Behavior Towards Pb(II), Zn(II), and Cd(II) Ions

Poly(1,4–cyclohexanedimethylene oxalate) was synthesized from oxalyl chloride and cis/trans–1,4–cyclohexandimethanol. The polymer was characterized by viscosity, FT–IR, NMR, elemental analysis, DSC, TGA, and SEM. The metal uptake behavior of the polymer towards Pb(II), Zn(II) and Cd(II) ions was studied by batch technique as a function of pH, temperature, concentration, contact time and by column technique. Their uptake increases slightly with pH reaching maximum at 6.00. The order of adsorption capacity was: Pb(II) andgt; Cd(II) andgt; Zn(II). The uptake of the polymer shows fittings to both Langmuir’s and Freundlich equations. ΔGand#176;, ΔHand#176; and ΔSand#176; were determined for Pb(II). The metal-unbound polymer was regenerated by treating the metal-sorbed polymer with 1.0 M HNO3 andgt;1.0 M HCl andgt;0.01 M EDTA.</jats:p

The Viability of Mobile Services (SMS and Cell Broadcast) in Emergency Management Solutions: An Exploratory Study

In this paper the path forward in location-based mobile phone warning systems is given against a concise backdrop of their deployment worldwide. Of relevance here is (i) how the systems are implemented using legislation, contractual service level agreement instruments or a hybrid approach, (ii) whether or not governments who deploy these systems will carry the cost of the deployment during an emergency or disaster, and (iii) whether or not carrier participation is mandated. Of particular importance are also the underlying technologies of this kind of emergency systems. To date, the short message service and cell broadcast service have been the main technologies to be utilised by governments in the application of location-based services in modern emergency management solutions. However, these technologies will most certainly be superseded by newer, more powerful capabilities. A comprehensive list of requirements for the future location-based emergency systems is presented also in this paper. In essence, these are recommendations to be adhered to if robust solutions using new technologies are to be deployed in a nation state.</p

The Viability of Mobile Services (SMS and Cell Broadcast) in Emergency Management Solutions: An Exploratory Study

In this paper the path forward in location-based mobile phone warning systems is given against a concise backdrop of their deployment worldwide. Of relevance here is (i) how the systems are implemented using legislation, contractual service level agreement instruments or a hybrid approach, (ii) whether or not governments who deploy these systems will carry the cost of the deployment during an emergency or disaster, and (iii) whether or not carrier participation is mandated. Of particular importance are also the underlying technologies of this kind of emergency systems. To date, the short message service and cell broadcast service have been the main technologies to be utilised by governments in the application of location-based services in modern emergency management solutions. However, these technologies will most certainly be superseded by newer, more powerful capabilities. A comprehensive list of requirements for the future location-based emergency systems is presented also in this paper. In essence, these are recommendations to be adhered to if robust solutions using new technologies are to be deployed in a nation state.</p

Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity

Essential oils of the leaves and flowers of Anthemis cotula L. (family Asteraceae) grown in Jordan were extracted by hydro-distillation and then analyzed by GC–MS. Sesquiterpenes hydrocarbons (SH) were the dominant components in the oils extracted from leaves and flowers of A. cotula. γ-Muurolene and aromadendrene, were the major compounds that were obtained from the flowers oil, while γ-muurolene and trans-cadinene ether were detected as major ingredients in the leaves extract. LC-MS analysis was carried out to identify the significant compounds from each extract. Additionally, butanol (B), aqueous methanol (M) and water (W) extracts prepared from the flowers and the leaves of A. cotula were analysed by LC-MS/MS. Apigenin and chlorogenic acid were the main constituents detected in the flowers’ alcoholic extracts and leaves’ aqueous extract. Moreover, the essential oils and all prepared extracts were assayed for their total antioxidant activity using the DPPH, ABTS, and ferrous ion chelating effect (FIC) assay methods. All investigated oils and extracts showed interesting activity as compared to the positive controls employed (α-tocopherol and ascorbic acid)