76 research outputs found

    Comparison of outcomes among the three groups.

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    PurposeTo inspect whether time management with radio frequency identification technology (RFID) reduces symptom onset-to-intravenous thrombolysis time (OTT) in acute ischemic stroke (AIS).MethodsIn the retrospective study, patients with AIS, transferred by Emergency Medical Services (EMS) to Hunan Provincial People’s Hospital between September 2019 to June 2022, divided into three groups, as traditional group, in-hospital RFID group and whole process RFID group. Baseline characteristics and time metrics were compared.ResultsAfter the whole emergency process applied with RFID time management, Door to intravenous thrombolysis time (DNT) was reduced from 125.00±43.16 min to 32.59±25.45 min (F = 121.857, pF = 10.377, pConclusionsTime management with RFID is effective in reducing OTT in AIS patients with thrombolysis treatment.</div

    Composition of emergency time metrics.

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    OTT: symptom onset to thrombolysis time; ODT: symptom onset to door time; DNT: door to needle for thrombolysis time; OCT: symptom onset to emergency call time; CAT: emergency call to ambulance time; ADT: ambulance on scene to door time; DCT: door to CT room time; CTT: CT to thrombolysis time.</p

    Comparison of demographic characteristics and clinical characteristics among the three groups.

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    Comparison of demographic characteristics and clinical characteristics among the three groups.</p

    Basic characteristics of participants in a case-control study of the effects of APOA5 <i>−1131T>C</i> on fasting plasma lipids and metabolic syndrome (MetS) risk in a Chinese population, 2010–2011.

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    <p>All continuous variables are expressed in means±standard deviation (SD) and categorical variables are expressed in number with percentage in parentheses.</p><p>Abbreviations: LDL, low-density lipoprotein, HDL, high-density lipoprotein, BMI, body mass index.</p>*<p><i>P</i><0.001 when comparing with controls.</p

    Effects of <em>APOA5 −1131T>C</em> (rs662799) on Fasting Plasma Lipids and Risk of Metabolic Syndrome: Evidence from a Case-Control Study in China and a Meta-Analysis

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    <div><p>The apolipoprotein A5 (<i>APOA5</i>) gene <i>−1131T>C</i> (rs662799) has been suggested to be involved in the pathway of lipid homeostasis and the development of metabolic syndrome (MetS). However, the findings are not consistent. To systematically evaluate the associations between <i>−1131T>C</i> polymorphism and fasting lipid parameters and the risk of MetS, we conducted a case-control study in a Chinese population and a meta-analysis. The findings from 1840 Chinese participants indicated that the C allele carriers had significantly higher fasting total cholesterol (TC), triglycerides (TG) and lower HDL-cholesterol (HDL-C) than the TT homozygotes carriers. The <i>−1131C</i> allele was also found to be significantly associated with increased risk of MetS (OR  =  1.40, 95% confidence interval (CI)  =  1.15, 1.69) compared to the TT homozygotes. In the meta-analysis of 51,868 participants from 46 East Asian studies, 26 European studies and 19 studies of other ethnic groups, the <i>−1131C</i> allele was associated with higher fasting TC (weighted mean difference (WMD)  =  0.08 mmol/L, 95% CI  =  0.05, 0.10, <i>P</i> = 1.74×10<sup>−9</sup>), TG (WMD  =  0.30 mmol/L, 95% CI  =  0.26, 0.33, <i>P</i> =  1.87×10<sup>−55</sup>), LDL-cholesterol (LDL-C) (WMD  =  0.04 mmol/L, 95% CI  =  0.02, 0.07, <i>P</i> = 0.002), and lower HDL-C (WMD  =  −0.05 mmol/L, 95% CI  =  −0.06,−0.04, <i>P</i> = 1.88×10<sup>−21</sup>), respectively. Based on 12 studies with 5,573 MetS cases and 8,290 controls from 5 East Asian studies, 5 European studies and 2 studies of other ethnic groups, the <i>−1131C</i> allele was associated with increased risk of MetS with an OR (95% CI)  =  1.33 (1.16, 1.53) in the overall population, 1.43 (1.29, 1.58) in East Asian and 1.30 (0.94, 1.78) in European populations. In conclusion, the <i>−1131C</i> allele may be associated with elevated levels of fasting TG, TC, LDL-C and decreased HDL-C, and increased risk of MetS, especially in East Asians.</p> </div

    RFID radio frequency identification device including a, wristband; b, reader.

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    RFID radio frequency identification device including a, wristband; b, reader.</p

    S1 Raw data -

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    PurposeTo inspect whether time management with radio frequency identification technology (RFID) reduces symptom onset-to-intravenous thrombolysis time (OTT) in acute ischemic stroke (AIS).MethodsIn the retrospective study, patients with AIS, transferred by Emergency Medical Services (EMS) to Hunan Provincial People’s Hospital between September 2019 to June 2022, divided into three groups, as traditional group, in-hospital RFID group and whole process RFID group. Baseline characteristics and time metrics were compared.ResultsAfter the whole emergency process applied with RFID time management, Door to intravenous thrombolysis time (DNT) was reduced from 125.00±43.16 min to 32.59±25.45 min (F = 121.857, pF = 10.377, pConclusionsTime management with RFID is effective in reducing OTT in AIS patients with thrombolysis treatment.</div

    Genotype and allele distributions of the <i>−1131T>C</i> between 905 cases of MetS and 935 controls and their association with MetS risk in a case-control study in a Chinese population, 2010–2011.

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    †<p><i>P</i> value was calculated by the <i>x</i><sup>2</sup> test.</p>‡<p>OR (odds ratio), 95% CI (confidence interval) and <i>P</i>-value were adjusted for age and sex.</p><p>Abbreviation: MetS, metabolic syndrome.</p

    Meta-analysis of the effects of <i>APOA5 −1131T>C</i> on fasting plasma lipids and MetS risk.

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    <p>Abbreviations: WMD, weighted mean difference; HWE, Hardy-Weinberg Equilibrium; MetS, metabolism syndrome.</p
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