The burn probability for the study area estimated by simulation.

<p>The burn probability for the study area estimated by simulation.</p

The study area and the distribution of fuel type in terms of dominant species.

<p>The study area and the distribution of fuel type in terms of dominant species.</p

Factors’ relative contribution to BP.

<p>Factors’ relative contribution to BP.</p

Dependent and exploratory variables included in this study.

<p>Dependent and exploratory variables included in this study.</p

Elevation, historical ignitions (1991–2010), settlements and roads in Longquan.

<p>Elevation, historical ignitions (1991–2010), settlements and roads in Longquan.</p

Results of the binary logistic regression model.

<p>Results of the binary logistic regression model.</p

Variables of RF model.

<p>Variables of RF model.</p

Box plots of different factors influencing burn probability.

<p>Error bars show 5th% and 95th% percentile of pixels in each bin. Cross symbols show 1st% and 99th% percentile. Fuel, upper row; Topography, center row; Human activity, lower row. Statistics were derived from a full sample of 43526 pixels in the region.</p

pH-Responsive Polyethylene Glycol Monomethyl Ether-ε-Polylysine-G-Poly (Lactic Acid)-Based Nanoparticles as Protein Delivery Systems

<div><p>The application of poly(lactic acid) for sustained protein delivery is restricted by the harsh pH inside carriers. In this study, we synthesized a pH-responsive comb-shaped block copolymer, polyethylene glycol monomethyl ether-ε-polylysine-<i>g</i>-poly (lactic acid) (PEP)to deliver protein (bovine serum albumin (BSA)). The PEP nanoparticles could automatically adjust the internal pH to a milder level, as shown by the quantitative ratio metric results. The circular dichroism spectra showed that proteins from the PEP nanoparticles were more stable than those from poly(lactic acid) nanoparticles. PEP nanoparticles could achieve sustained BSA release in both <i>in vitro</i> and <i>in vivo</i> experiments. Cytotoxicity results in HL-7702 cells suggested good cell compatibility of PEP carriers. Acute toxicity results showed that the PEP nanoparticles induced no toxic response in Kunming mice. Thus, PEP nanoparticles hold potential as efficient carriers for sustained protein release.</p></div

TEM image of PEP NPs.

<p>TEM image of PEP NPs.</p