sj-docx-1-acr-10.1177_02841851221127271 - Supplemental material for Alterations of static and dynamic functional network connectivity in acute ischemic brainstem stroke

Supplemental material, sj-docx-1-acr-10.1177_02841851221127271 for Alterations of static and dynamic functional network connectivity in acute ischemic brainstem stroke by Jian Zhang and Yi Chang in Acta Radiologica</p

The statistics of the cancer datasets used in this study.

The statistics of the cancer datasets used in this study.</p

An illustration of the proposed framework.

The biological process activity of each sample is obtained by core genes regression and used as the outcome of the casual model. The casual model consists of an inference network to calculate the mean and variance of P(Z|X,y,m) and a model network to recover P(Z,X,y,m).</p

The causal structure of the mutation in the cancer biological process.

M is a binary treatment variable, i.e., whether a gene mutated or not; Y is the outcome, e.g., the cell proliferation activity. X is the observed confounders, i.e., the mutation matrix of covariant genes; Z is the unobserved confounders which can be learned from X, e.g., micro-environment stress, so another role for X is a proxy variable for Z; Confounder affect both the treatment and the outcome and may lead to the erroneous association.</p

A Novel Two-Dimensional Allotrope of Silicon Grown on Al(111): A Case Study of the Interface Effect

Based on density functional calculations, a novel planar allotrope of silicon on Al(111) is rationally designed by using the lowest energy principle, which is also predicted to be stable above room temperature to suggest the possibility for its fabrication. The corresponding free-standing sheet would be buckled though the structural characteristics still remain, whose stability has also been evaluated in detail. It has been found to have strong anisotropic properties to be as hard as silicene in a specific direction and to be very soft in the perpendicular direction. Surprisingly, a peculiar negative Poisson’s ratio showing unusual mechanical properties is also found. The indirect bandgap of 0.14 eV of the free-standing sheet could be closed by applying tensile strain. Interestingly, the Dirac cone of the orthogonal lattice allotrope sheet can be obtained by applying biaxial strain, for which the velocity of the charge carriers could reach 5.97 × 105 m/s. In addition, the hydrogenated sheet is also quite stable and may find usage for sunlight absorption, field-effect transistor, etc., which may be decorated with Ti, Fe, or Co adsorptions to have half-metallic conducting properties for spin filtering

The Mann-Whitney U test (M.W.) analysis reflects the significant differences between mutated groups and non-mutated groups of mutated genes with high ATE values in the activity of DNA replication (DR) for 10 cancers.

The Mann-Whitney U test (M.W.) analysis reflects the significant differences between mutated groups and non-mutated groups of mutated genes with high ATE values in the activity of DNA replication (DR) for 10 cancers.</p

The causal effect of the top 10 genes with highest mutation rates on EMT.

The causal effect of the top 10 genes with highest mutation rates on EMT.</p

The Mann-Whitney U test (M.W.) analysis shows there is no significant differences between mutated groups and non-mutated groups of mutated genes with high mutation rates in the activity of EMT process for 10 cancers.

The Mann-Whitney U test (M.W.) analysis shows there is no significant differences between mutated groups and non-mutated groups of mutated genes with high mutation rates in the activity of EMT process for 10 cancers.</p

The Mann-Whitney U test (M.W.) analysis reflects the significant differences between mutated groups and non-mutated groups of mutated genes with high ATE values in the activity of EMT process for 10 cancers.

The Mann-Whitney U test (M.W.) analysis reflects the significant differences between mutated groups and non-mutated groups of mutated genes with high ATE values in the activity of EMT process for 10 cancers.</p

The causal effect of the top 10 genes with highest mutation rates on DNA replication.

The causal effect of the top 10 genes with highest mutation rates on DNA replication.</p