Kaplan Meier curves of disease free survival of risk groups for TNBC patients.

<p>The patients were stratified into different risk groups. Two low basal (EGFR≤15% and CK5/6≤50%) risk groups: group 1 (n = 20) with low expressions/values of EGFR (≤15%), CK5/6 (≤50%), Ki-67 (≤50%), pT (≤ 3), and pN (≤ 1), and group 2 (n = 30) with low expressions of EGFR and CK5/6, and any high expressions/values of Ki-67, pT, and pN. Two high basal risk groups: group 3 (n = 106) with single high basal expression (EGFR>15% or CK5/6>50%), and group 4 (n = 36) with double high basal expressions (EGFR>15% and CK5/6>50%).</p

T2 mapping images (A-F) and T2* mapping (A-F) images of rabbit cartilage at different time points after surgery (W2, W4, W8, W12, W16, and W20).

<p>The cartilage was integral and had moderate to slightly high linear homogeneous signal (A-B). The cartilage had moderate to slightly high signal and poor contrast with adjacent synovial fluid, adipose tissue and myeloid tissue(C-D). The cartilage was not integral and had slightly high heterogeneous signal(E-F).</p

Changes in COMP levels in the serum at different points after surgery.

<p>The COMP level peaked at time point of W12 and decreased at W16. Significant differences were found between the control group and all OA groups except the W20 group. Asterisks indicate significant differences with paired-samples T tests.</p

Patients characteristics.

<p>Patients characteristics.</p

The scatter diagram of T2 values and Mankin scores.

<p>A positive correlation was found between the two variables (R² = 0.794, <i>P</i><0.001) using linear regression analysis. A correlation was also found between T2 and T2* values (<i>P</i><0.001). N = 18.</p

TNBC patient risk groups stratified by EGFR, CK5/6, Ki-67, pT and pN.

<p>TNBC patient risk groups stratified by EGFR, CK5/6, Ki-67, pT and pN.</p

The Mankin score increased at the different time points after surgery with improved Hulth method.

<p>Asterisks indicate significant differences.</p

T2* values were elevated after W2 compared with the control group, but significant differences appeared from W8 to W20.

<p>Asterisks indicate significant differences with paired-samples T tests.</p

Immunoreactivity of 69-yr-old patient with T1bN0M0 TNBC.

<p>(A) Hematoxylin and Eosin (H&E), (B) EGFR (>70%), (C) CK5/6 (>70%), (D) ER, (E) PR, (F) HER2, (G) Ki-67 (>60%), and (H) P53 (>90%). The patient was undergone BCT, had 3.8 event free survival and 22.8 months overall survival.</p

Scattergrams plotting individual serum biomarker concentration against T2* relaxation time values.

<p>T2* relaxation times correlated significantly with BMP-2, CTX-II and COMP (D, R² = 0.23, <i>P</i> = 0.043; E, R² = 0.4, <i>P</i> = 0.005; F, R² = 0.28, <i>P</i> = 0.025). N = 18.</p