Additional file 2 of The role of 99mTc-DPD bone SPECT/CT in the management of growth disturbance of the long bones in pediatric patients: a retrospective observational study

Supplementary Material

Additional file 1 of The role of 99mTc-DPD bone SPECT/CT in the management of growth disturbance of the long bones in pediatric patients: a retrospective observational study

Supplementary Material

Patient characteristics.

Patient characteristics.</p

Univariate and multivariate analyses for determining SUV_max.

Univariate and multivariate analyses for determining SUVmax.</p

Correlations of AR with expression of FA β-oxidation-associated genes and GLUT1.

AR expression show positive correlation with FA oxidation (A) and negative correlation with GLUT1 expression (B). AR, expression level of androgen receptor gene; FA, fatty acid; FA oxidation, gene set enrichment score of FA β-oxidation-associated genes; GLUT1, expression level of GLUT1 (SLC2A1) gene.</p

Univariate and multivariate analyses for determining SUV_max using ≥ 10% for AR positivity.

AR: androgen receptor. (DOCX)</p

Glycolysis-related genes from the REACTOME_GLYCOLYSIS.

(DOCX)</p

Androgen receptor expression according to clinicopathologic characteristics.

Androgen receptor expression according to clinicopathologic characteristics.</p

SUV_max according to androgen receptor status with varying cutoff values for androgen receptor positivity.

AR: androgen receptor. (DOCX)</p

Correlations among AR, SUV_max, and glycolysis-associated genes expressions analyzed using GSE135565 database.

SUVmax was well correlated with glycolysis score (A). A negative correlation between AR expression and SUVmax was observed (B). The AR expression is inversely correlated with glycolysis score (C). AR, expression level of androgen receptor gene; Glycolysis score indicates how close gene expression pattern of a sample is, to expected expression pattern of the glycolysis-related gene set.</p