Copper coin-embedded printed circuit board for heat dissipation: manufacture, thermal simulation and reliability

Purpose - The purpose of this paper is to form copper coin-embedded printed circuit board (PCB) for high heat dissipation. Design/methodology/approach - Manufacturing optimization of copper coin-embedded PCB involved in the design and treatment of copper coin, resin flush removal and flatness control. Thermal simulation was used to investigate the effect of copper coin on heat dissipation of PCB products. Lead-free reflow soldering and thrust tests were used to characterize the reliable performance of copper coin-embedded PCB. Findings - The copper coin-embedded PCB had good agreement with resin flush removal and flatness control. Thermal simulation results indicated that copper coin could significantly enhance the heat-dissipation rate by means of a direct contact with the high-power integrated circuit chip. The copper coin-embedded PCB exhibited a reliable structure capable of withstanding high-temperature reflow soldering and high thrust testing. Originality/value - The use of a copper coin-embedded PCB could lead to higher heat dissipation for the stable performance of high-power electronic components. The copper coin-embedded method could have important potential for improving the design for heat dissipation in the PCB industry

Effects of surface-functionalized aluminum nitride on thermal, electrical, and mechanical behaviors of polyarylene ether nitrile-based composites

Aluminum nitride (AlN) with high thermal conductivity was blended in polyarylene ether nitrile (PEN) to obtain a composite system. A ball milling process could provide AlN particles of smaller size with higher surface silylation for homogeneous particle distribution in polymeric matrix. Thermal, electrical, and mechanical behaviors of the produced composites were characterized to investigate the effects of particles on the performance of PEN-based composites with functionalized AlN. The composite exhibited thermal conductivity of 0.779 W m−1 K−1, a dielectric constant of 7.7, dielectric loss of 0.032, electrical resistivity of 1.39 GΩ.cm, and break strength of 36 N when the fraction of functionalized AlN increased to 42.3 vol%. A fitted equation based on the improved Russell's model could effectively predict a trend for thermal conductivity of the composite systems with consideration of interfacial resistance between AlN and surrounding PEN

Characterization and application of aggregated porous copper oxide flakes for cupric source of copper electrodeposition

Copper oxide was prepared with thermal decomposition of basic copper carbonate to complement the concentration of cupric ions for copper electrodeposition in a plating system with insoluble anode. Copper oxide particles with a structure of aggregated porous flakes had a wide size distribution ranging from 100 nm to 100 μm. Copper oxide exhibited a dissolution rate of about 15 s in 12.5 vol% H2SO4 solution. During copper electrodeposition, copper deposits with fine growth formed in the electrolyte with stable cupric concentration provided by rapid dissolution of copper oxide

Properties and application of polyimide-based composites by blending surface functionalized boron nitride nanoplates

Properties and application of polyimide-based composites by blending surface functionalized boron nitride nanoplate

Regulated proteolysis of MutSγ controls meiotic crossing over, He et al

This dataset includes unprocessed gels and cytology images of the paper "Regulated proteolysis of MutSγ controls meiotic crossing over " for Molecular Cel

raw data paper titled "Regulated proteolysis of MutSγ controls meiotic crossing over "

This dataset includes unprocessed gels and cytology images of the paper "Regulated proteolysis of MutSγ controls meiotic crossing over " for Molecular Cel

Small business financing : survey evidence in west Texas

We investigate the financial sources of small firms through a survey of sample firms from West Texas. Evidence shows that the two most common start-up financing alternatives are personal savings and commercial bank loans. Commercial banks remain the most popular source of financing for present and future needs, followed by leasing companies and credit unions. Informal types of financing such as business credit cards, and trade credit are used in addition to lines of credit for transaction and working capital purposes. Firms typically review their financial performance monthly and use common cash balances as the primary financial tool.</p

Raw data in text format from Effect of components on the curing of glycidyl azide polymer spherical propellant through rheological method

Raw data of four curing system (A: IPDI/GAP Spherical Propellant (pure curing system); B: 0.1Cl-20 curing system; C: 0.1AP curing system; D: 0.1RDX curing system) at 50℃, 55℃, 60℃ and 65℃

Efficacy and safety of Venetoclax-based regimens in relapsed or refractory multiple myeloma: a systematic review and meta-analysis of prospective clinical trials

Multiple myeloma (MM) is an incurable malignancy. Venetoclax (VEN) shows a meaningful effect in MM patients who are relapsed or refractory (RR) to previous standard therapies. This study aimed to assess the efficacy and safety of VEN-based treatments in RR MM patients. Comprehensive studies were searched in PubMed, Embase, Web of Science and Cochrane library. Efficacy was assessed by overall response rate (ORR), strict complete response rate (sCR), complete response rate (CR), very good partial response rate (VGPR) and partial response rate (PR). Seven studies containing 482 subjests were included. The pooled ORR, ≥ CR (sCR + CR), VGPR and PR were 68% (51%–85%), 24% (13%–35%), 25% (17%–34%) and 17% (11%–24%) respectively. Multi-drug treatments were superior to VEN ± dexamethasone (Dex) treatments in ORR (82% vs 42%, p = .003) and ≥ CR (36% vs 7%, p  VEN-containing regimens could be suggested as effective and safe treatments to RR MM patients with t(11;14) or high BCL-2 levels.</p

Image_4_Comprehensive analysis of aerobic glycolysis-related genes for prognosis, immune features and drug treatment strategy in prostate cancer.tif

BackgroundThe dysregulated expression of aerobic glycolysis-related genes is closely related to prostate cancer progression and metastasis. However, reliable prognostic signatures based on aerobic glycolysis have not been well established.MethodsWe screened aerobic glycolysis-related gene modules by weighted gene co-expression network analysis (WGCNA) and established the aerobic glycolysis-related prognostic risk score (AGRS) by univariate Cox and lasso-Cox. In addition, enriched pathways, genomic mutation, and tumor-infiltrating immune cells were analyzed in AGRS subgroups and compared to each other. We also assessed chemotherapeutic drug sensitivity and immunotherapy response among two subgroups.ResultsAn aerobic glycolysis-related 14-gene prognostic model has been established. This model has good predictive prognostic performance both in the training dataset and in two independent validation datasets. Higher AGRS group patients had better immunotherapy response. Different AGRS patients were also associated with sensitivity of multiple prostate cancer chemotherapeutic drugs. We also predicted eight aerobic glycolysis-related small-molecule drugs by differentially expressed genes.ConclusionIn summary, the aerobic glycolysis-derived signatures are promising biomarkers to predict clinical outcomes and therapeutic responses in prostate cancer.</p