6 research outputs found

    Hyperreflective foci on SD-OCT before and after treatment with anti-VEGF.

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    Foveal centered spectral domain optical coherence tomography (SD-OCT) B-scan image of a patient with DME before (A) and after (B) 3 injections with anti-VEGF. Black arrows indicate hyperreflective foci, within 3000 μm of the fovea (dashed bars).</p

    Differences between before and after treatment with anti-VEGF.

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    Mean changes in central retinal thickness (A), visual acuity (B) and number of hyperreflective foci (C) at baseline and after 3 injections with anti-VEGF. The bars represent mean ± 95% confidence interval. *P<0.05.</p

    Difference in number of HF at baseline, and change in HF between eyes with adequate response versus insufficient response.

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    Mean number of HF at baseline in groups based on insufficient and adequate CRT response (A); insufficient and adequate VA response (B); and insufficient and adequate combined CRT + VA response (C). Mean change in number of HF in groups based on insufficient and adequate CRT response (D); insufficient and adequate VA response (E); and insufficient and adequate combined CRT + VA response (F). The distribution of HF in the inner and outer retinal layers is displayed as a percentage. The values represent the odds ratio with corresponding 95% confidence interval and p-value. The odds ratio of adequate response is 1.106, which can be interpreted as an increase, or chance, for adequate response by 10.6% for every HF at baseline; when the number of HF at baseline increases by 10, the chance for adequate response increases exponentially by 1.10610 = 2.74 or 274%. The bars represent mean ± 95% confidence interval and are based on descriptive statistics. *P<0.05.</p
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