The Right to Be Cold: One Woman’s Fight to Protect the Arctic and Save the Planet from Climate Change by Sheila Watt-Cloutier

Review of Sheila Watt-Cloutier\u27s The Right to Be Cold: One Woman\u27s Fight to Protect the Arctic and Save the Planet from Climate Change

“Mistakes” in the Sound Archive: An Interview with Leah Van Dyk

Mathieu Aubin reached out to Leah Van Dyk shortly after she was awarded a Killam scholarship for her research in environmental humanities. While Van Dyk's research focuses on environmental humanities, pedagogy, and accessibility, she is also often thinking about serendipitous moments activated through sound

2017 Research & Innovation Day Program

A one day showcase of applied research, social innovation, scholarship projects and activities.https://first.fanshawec.ca/cri_cripublications/1004/thumbnail.jp

The Right to Be Cold: One Woman’s Fight to Protect the Arctic and Save the Planet from Climate Change by Sheila Watt-Cloutier

Review of Sheila Watt-Cloutier\u27s The Right to Be Cold: One Woman\u27s Fight to Protect the Arctic and Save the Planet from Climate Change

Audio Time Travel: An Interview with Annie Murray

I first met Annie Murray in 2017 at a job interview (she was the interviewer, I the interviewee—thankfully I got the job), and in 2018 Annie asked me to join the SpokenWeb team as a research assistant. Four years later, we sit down—through our respective laptops—to chat about all things audio. As I soon found out, when it comes to thinking about sound, access, and vulnerability, Annie approaches listening as a joyful and potential-filled practice

Epigenetic and Conventional Regulation Is Distributed among Activators of FLO11 Allowing Tuning of Population-Level Heterogeneity in Its Expression

Epigenetic switches encode their state information either locally, often via covalent modification of DNA or histones, or globally, usually in the level of a trans-regulatory factor. Here we examine how the regulation of cis-encoded epigenetic switches controls the extent of heterogeneity in gene expression, which is ultimately tied to phenotypic diversity in a population. We show that two copies of the FLO11 locus in Saccharomyces cerevisiae switch between a silenced and competent promoter state in a random and independent fashion, implying that the molecular event leading to the transition occurs locally at the promoter, in cis. We further quantify the effect of trans regulators both on the slow epigenetic transitions between a silenced and competent promoter state and on the fast promoter transitions associated with conventional regulation of FLO11. We find different classes of regulators affect epigenetic, conventional, or both forms of regulation. Distributing kinetic control of epigenetic silencing and conventional gene activation offers cells flexibility in shaping the distribution of gene expression and phenotype within a population