Highly Enantio- and Diastereoselective Mannich Reactions of Chiral Ni(II) Glycinates with Amino Sulfones. Efficient Asymmetric Synthesis of Aromatic α,β-Diamino Acids

This paper describes a practical, enantio- and diastereoselective Mannich reaction between a chiral Ni(II) complex of glycine 1 and α-amino sulfones 2, involving the creation of a carbon−carbon bond and two stereogenic centers in a single operation; it represents an attractive route to the synthesis α,β-diamino acids

Supplemental_File – Supplemental material for Biochar of distillers’ grains anaerobic digestion residue: Influence of pyrolysis conditions on its characteristics and ammonium adsorptive optimization

Supplemental material, Supplemental_File for Biochar of distillers’ grains anaerobic digestion residue: Influence of pyrolysis conditions on its characteristics and ammonium adsorptive optimization by Xuebo Zheng, Ting Shi, Wenjing Song, Lei Xu and Jianxin Dong in Waste Management & Research</p

Synthesis of a Healthy Sweetener d‑Tagatose from Starch Catalyzed by Semiartificial Cell Factories

d-Tagatose is one of the several healthy sweeteners that can be a substitute for sucrose and fructose in our daily life. Whole cell-catalyzed phosphorylation and dephosphorylation previously reported by our group afford a thermodynamic-driven strategy to achieve tagatose production directly from starch with high product yields. Nonetheless, the poor structural stability of cells and difficulty in biocatalyst recycling restrict its practical application. Herein, an efficient and stable semiartificial cell factory (SACF) was developed by constructing an organosilica network (OSN) artificial shell on the cells bearing five thermophilic enzymes to produce tagatose. The OSN artificial shell, the thickness of which can be regulated by changing the tetraethyl silicate concentration, exhibited tunable permeability and superior mechanical strength. In contrast with cells, SACFs showed a relative activity of 99.5% and an extended half-life from 33.3 to 57.8 h. Over 50% of initial activity was retained after 20 reuses. The SACFs can catalyze seven consecutive reactions with tagatose yields of over 40.7% in field applications

Highly Enantio- and Diastereoselective Mannich Reactions of Chiral Ni(II) Glycinates with Amino Sulfones. Efficient Asymmetric Synthesis of Aromatic α,β-Diamino Acids

This paper describes a practical, enantio- and diastereoselective Mannich reaction between a chiral Ni(II) complex of glycine 1 and α-amino sulfones 2, involving the creation of a carbon−carbon bond and two stereogenic centers in a single operation; it represents an attractive route to the synthesis α,β-diamino acids

Microencapsulated Diepoxy-Functionalized Ionic Liquids to the Design of Self-Healable Epoxy Networks

An extrinsic self-healing mechanism based on microencapsulated healing agents represents an original way to produce self-healable thermosetting materials without modifying the structural architecture of the co-monomers. In this work, self-healing was achieved through poly­(melamine–formaldehyde) (PMF) microcapsules containing a polymerizable diepoxidized ionic liquid monomer denoted as ILEM. First, a synthetic route to design ILEM@PMF microcapsules via in situ polymerization was developed and optimized through the choice of surfactants, core/shell ratios, and stirring speeds. Then, the obtained microcapsules (10 wt %) were incorporated into three different epoxy–amine networks and their effects on the morphology, thermal behavior, i.e., glass transition temperature (Tg) and degradation temperature (Td), as well as on the mechanical properties were investigated. In addition, a pre-crack was generated with a fresh razor blade into the center groove of the epoxy networks and their self-healing performances were observed by scanning electron microscopy before and after the curing process

Highly Enantio- and Diastereoselective Mannich Reactions of Chiral Ni(II) Glycinates with Amino Sulfones. Efficient Asymmetric Synthesis of Aromatic α,β-Diamino Acids

This paper describes a practical, enantio- and diastereoselective Mannich reaction between a chiral Ni(II) complex of glycine 1 and α-amino sulfones 2, involving the creation of a carbon−carbon bond and two stereogenic centers in a single operation; it represents an attractive route to the synthesis α,β-diamino acids

Additional file 7: of Genome-wide discovery and characterization of flower development related long non-coding RNAs in Prunus mume

The differential expressed lncRNAs in this study. (XLS 63 kb

Additional file 8: of Genome-wide discovery and characterization of flower development related long non-coding RNAs in Prunus mume

The precursor analysis of the new lncRNAs. (XLS 23 kb

Additional file 5: of Genome-wide discovery and characterization of flower development related long non-coding RNAs in Prunus mume

Gene ontology (a) and pathway-enrichment (b) analysis for DEGs. (JPG 695 kb

Additional files 1: of Gestational weight gain in Chinese women -- results from a retrospective cohort in Changsha, China

Table S1. Subgroup analysis of comparison of adverse pregnancy outcomes between different gestational weight gain groups in the pre-pregnancy BMI 23.0–24.9 strata. (DOC 47 kb