Frequencies of abnormal TDI during the course of the illness.

<p>Percentages of DF (dotted lines) and DHF cases (solid lines) with low septal and lateral S wave (A, B) and septal and lateral Ea wave (C, D) and high E/Ea ratios (E) determined based on published age-specific normal values (21). * different from DF (<i>P</i> < .05).</p

Tissue Doppler imaging studies of LV function on the first study day in subjects with dengue.

<p>Values represent mean (SE), or number of cases.</p><p>^a two DHF cases did not have ultrasonography performed on the day of enrollment and were not included in this analysis. Differences between groups were analyzed by ANOVA with post hoc test or by Man Whitney’s test.</p><p>^<i>b</i>, ^<i>c</i> different from DHF without leakage at <i>P</i> < .05, and .005 respectively).</p><p>Tissue Doppler imaging studies of LV function on the first study day in subjects with dengue.</p

Left ventricular functions in dengue by fever day.

<p>Ejection fraction (A), early diastolic LV inflow flow (B), and late diastolic LV inflow (C) of dengue fever (dotted line) and dengue hemorrhagic fever cases (solid line) over the course of the illness. Fever day 0 denotes day of defervescence. * different from dengue fever (<i>P</i> < .05). The numbers of cases were: fever-day -3 (DF 4, DHF 5), fever-day-2 (DF 13, DHF 9), fever-day-1(DF 43, DHF 26), fever-day-0(DF 104, DHF 56), fever-day+1(DF 119, DHF 62), fever-day+2(DF 70, DHF 60), fever-day+3(DF 13, DHF 38).</p

Laboratory findings and cardiac function measurements on the first study day in subjects with dengue.

<p>Values represent mean (SE), or number of cases.</p><p>^a two DHF cases did not have ultrasonography performed on the day of enrollment and were not included in this analysis. Differences between groups were analyzed by ANOVA with post hoc test or by Man Whitney’s test.</p><p>^<i>b</i>, ^<i>c</i> different from DHF without leakage at <i>P</i> < .005, and .05 respectively).</p><p>Laboratory findings and cardiac function measurements on the first study day in subjects with dengue.</p

Plasma troponin-T levels in individual DF (white circles) or DHF cases (black circles) during the course of the illness.

<p>The horizontal line indicates a cut-off for an abnormal value at 30 pg/ml.</p

Clinical characteristics of study participants.

<p>Fever day and laboratory findings were from the day of study entry. Values represent mean (SE), or number of cases.</p><p>^<i>a</i> Different from non-dengue cases (<i>P</i> < .05)</p><p>^<i>b</i> different from DF (<i>P</i> < .05).</p><p>Clinical characteristics of study participants.</p

Tissue Doppler image of LV functions by fever day.

<p>Left ventricular lateral (A) and septal S wave (B), LV mean performance index (MPI) (C), lateral (D) and septal (E) annulus movement during early diastole, lateral (F) and septal (G) annulus movement during late diastole, and lateral (H) and medial (I) E/Ea ratios of dengue fever (dotted line) and dengue hemorrhagic fever (solid line) cases over the course of the illness. Fever day 0 denotes day of defervescence. * different from DF (<i>P</i> < .05). The numbers of cases were: fever-day -3 (DF 4, DHF 5), fever-day-2 (DF 13, DHF 9), fever-day-1(DF 43, DHF 26), fever-day-0(DF 104, DHF 56), fever-day+1(DF 119, DHF 62), fever-day+2(DF 70, DHF 60), fever-day+3(DF 13, DHF 38).</p

Comparison between cardiac function at fever day +1 and early convalescence.

<p>^a<i>P</i> value comparing values at fever day +1 and early convalescence (Student’s paired t-test).</p><p>Comparison between cardiac function at fever day +1 and early convalescence.</p

Hemodynamic status and plasma leakage in dengue by fever day.

<p>Heart rate (A), systolic blood pressure (B), diastolic blood pressure (C), inferior vena cava diameter (D), mean cardiac index (E), systemic vascular resistance (F), frequencies of cases with a pleural effusion or ascites (G), and daily fluid intake (H) of dengue fever (dotted line) and dengue hemorrhagic fever cases (solid line) over the course of the illness. Fever day 0 denotes day of defervescence. * different from dengue fever cases (<i>P</i> < .05). The numbers of cases were: fever-day -3 (DF 4, DHF 5), fever-day-2 (DF 13, DHF 9), fever-day-1(DF 43, DHF 26), fever-day-0(DF 104, DHF 56), fever-day+1(DF 119, DHF 62), fever-day+2(DF 70, DHF 60), fever-day+3(DF 13, DHF 38).</p