865 research outputs found

    A unified origin for the 3D magnetism and superconductivity in Nax_xCoO2_2

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    We analyze the origin of the three dimensional (3D) magnetism observed in nonhydrated Na-rich Nax_xCoO2_2 within an itinerant spin picture using a 3D Hubbard model. The origin is identified as the 3D nesting between the inner and outer portions of the Fermi surface, which arise due to the local minimum structure of the a1ga_{1g} band at the Γ\Gamma-A line. The calculated spin wave dispersion strikingly resembles the neutron scattering result. We argue that this 3D magnetism and the spin fluctuations responsible for superconductivity in the hydrated systems share essentially the same origin.Comment: 5pages, 6figure

    Correlation of Ischemia-Modified Albumin with SOFA and APACHE II Scores in Preoperative Patients with Colorectal Cancer

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    Purpose. Critical illnesses are assessed according to the sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II. Circulating ischemia-modified albumin (IMA) is a biomarker generated under ischemic and oxidative conditions and may reflect disease severity in preoperative patients. This study investigated the correlations of IMA with SOFA and APACHE II scores in inpatients admitted for colorectal surgery. Methods.We examined 27 patients with advanced colorectal cancers (mean age 69 years, men/women = 15/12). Correlations between SOFA and APACHE II scores in addition to preoperative serum IMA and C-reactive protein (CRP) levels were analyzed. Results. The mean IMA level was 0.5AU, and the median CRP level was 0.6mg/dL. Median scores for SOFA and APACHE II were 2 and 12 points, respectively. Significant positive correlations between IMA and SOFA ( = 0.45, \u3c 0.05) and IMA and APACHE II ( = 0.45, \u3c 0.05) were identified which remained significant in confounder-adjusted analyses. In contrast, weak correlations were observed between CRP and the SOFA and APACHE II scores. Conclusions.The positive correlations between IMA and both SOFA and APACHE II scores suggest that serum IMA measurements reflect the severity of systemic failure in patients admitted for colorectal surgery in the preoperative phase

    Resource Variations across the Landscape Mediate the Impact of Grazing on Vegetation in Mongolian Rangeland under High Climatic Variability

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    Assessment of grazing-induced degradation of arid and semi-arid rangelands with stochastic rainfall regimes is challenging. For the last two decades, rangeland ecologists have been discussing the relative importance of biotic and abiotic factors in controlling vegetation dynamics. According to the non-equilibrium concept, which emerged as a new paradigm to describe ecosystems in highly variable and poorly predictable environments, vegetation dynamics are driven primarily by abiotic factors such as rainfall, rather than by internal biotic regulation (e.g. grazing impact). Although a number of studies have emphasized the non-equilibrium nature of most rangelands, they have produced inconsistent results and there is still no consensus on the relative importance of grazing impact. Alternatively, recent studies have suggested that a continuum of systems exists, rather than a stark dichotomy between equilibrium and non-equilibrium rangelands. Moreover, theoretical studies have predicted that, in addition to climatic variability, resource variations occurring in space and time as a result of landscape heterogeneity should be taken into account in assessments of grazing impact. However, there have been few empirical studies of the role of resource variations in either mitigating or enhancing the impacts of grazing on vegetation. This study explores the impact of grazing strategies on vegetation in Mongolian rangelands under high climatic variability. Specifically, it is focused on key resource areas, defined in terms of the key factor determining livestock population, and thus the ability to forage during drought. Based on the prediction proposed by Illius and O’Connor (1999) that animal numbers are regulated in a density-dependent manner by the limited forage availability in key resource areas, we established and examined the hypothesis that grazing impacts would be greater in key resource areas than in other areas even in Mongolian rangelands

    Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

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    We investigated the clinical efficacy and safety of tocilizumab (a humanized anti-IL-6 receptor antibody) monotherapy in active rheumatoid arthritis (RA) patients with an inadequate response to low dose methotrexate (MTX). In a multicenter, double-blind, randomized, controlled trial, 125 patients were allocated to receive either tocilizumab 8 mg/kg every 4 weeks plus MTX placebo (tocilizumab group) or tocilizumab placebo plus MTX 8 mg/week (control group) for 24 weeks. The clinical responses were measured using the American College of Rheumatology (ACR) criteria and the Disease Activity Score in 28 joints. Serum vascular endothelial growth factor (VEGF) levels were also monitored. At week 24, 25.0% in the control group and 80.3% in the tocilizumab group achieved ACR20 response. The tocilizumab group showed superior ACR response criteria over control at all time points. Additionally, serum VEGF levels were significantly decreased by tocilizumab treatment. The overall incidences of adverse events (AEs) were 72 and 92% (serious AEs: 4.7 and 6.6%; serious infections: 1.6 and 3.3%) in the control and the tocilizumab groups, respectively. All serious adverse events improved by adequate treatment. Tocilizumab monotherapy was well tolerated and provided an excellent clinical benefit in active RA patients with an inadequate response to low dose MTX

    Improvement of Electrochemical Stability Using the Eutectic Composition of a Ternary Molten Salt System for Highly Concentrated Electrolytes for Na-Ion Batteries

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    The increase in the concentration of electrolytes for secondary batteries has significant advantages in terms of physicochemical and electrochemical performance. This study aims to explore a highly concentrated electrolyte for Na-ion batteries using a ternary salt system. The eutectic composition of the Na[N(SO₂F₂]–Na[N(SO₂F)(SO₂CF₃)]–Na[SO₃CF₃] ternary molten salt system increases solubility into an organic solvent, enabling the use of highly concentrated electrolytes for Na-ion batteries. The ternary salt system achieved concentrations of 5.0 m (m = mol kg⁻¹) with propylene carbonate (PC), 2.9 m with dimethoxyethane, 2.0 m with ethylene carbonate/dimethyl carbonate, and 3.9 m with ethylene carbonate/diethyl carbonate. The highly concentrated electrolyte of 5.0 m in PC suppressed Al corrosion and exhibited better oxidative stability. Stable electrochemical performance using hard carbon/NaCrO₂ in the full-cell configuration introduces a new strategy to explore highly concentrated electrolytes for secondary batteries

    Use of a Rigid Curved Laryngoscope for Removal of a Fish Bone in the Hypopharynx

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    Foreign body ingestion is a commonly encountered clinical problem. In particular, sharp foreign bodies lodged in the esophagus or hypopharynx can cause complications and require urgent removal. Removal by flexible esophagogastroduodenoscopy or rigid esophagoscopy is the treatment of choice and has high success rates, but cases in which these methods are unsuccessful must be treated with an external incision. A 62-year-old man was referred for a fish bone lodged in the hypopharynx that could not be removed by flexible esophagogastroduodenoscopy. We removed the bone transorally using a specially designed rigid curved laryngoscope. Based on our experience, this method may have clear practical value due to advantages of a wide field of view and use of multiple rigid forceps. Indications may be limited, but this novel method may reduce the limitations of noninvasive removal of foreign bodies

    Solitary pancreatic metastasis from renal cell carcinoma.

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    A rare case of resectable solitary pancreatic metastasis from a renal cell carcinoma is reported. The patient was a 57-year-old man who presented with epigastralgia. He had undergone a radical nephrectomy of the right side 30 months previously. The diagnosis of pancreatic metastasis was based on the patient's past history and angiographic demonstration of typical hypervascular tumor staining. Histological examination was confirmatory. The patient was successfully treated by pancreaticoduodenectomy followed by alpha-interferon administration. As of 6 months after surgery, he remains well.</p
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