What makes neighbourhood-level commercial centres attractive for neighbourhood residents?

Neighbourhood commercial centres (NCC) are dynamic hubs that provide essential goods, promote community bonds and drive economic growth. Despite numerous studies on shopping behaviour, there remains a notable gap in understanding how transportation and shopping centre-related factors collectively shape the attractiveness of the NCCs, especially in developing countries like India. This research aims to understand why some NCCs outperform others in terms of attractiveness. This study proposes the neighbourhood commercial centre attractiveness index (NCCAI), which is developed by collecting 455 samples from 13 NCCs with the help of a primary survey to understand how different factors influence the attractiveness of NCCs in the Indian planned city context. The study used principal component analysis (PCA) and identified five major components that significantly contribute to NCC’s attractiveness. Further, the weightage of the components was determined through two distinct approaches: one based on PCA results and the other utilising the analytic hierarchy process (AHP) with expert opinion data. Finally, the more reliable weights from these two methodologies were selected using analysis of covariance (ANCOVA). The NCCAI can help urban planners, store owners and retail managers, providing data-driven insights to enhance overall NCC attractiveness. The decomposable nature of NCCAI allows for component score breakdown, enabling planners and policymakers to allocate resources strategically.</p

Microgels as Smart Polymer Colloids for Sensing and Environmental Remediation

Stimuli-responsive microgels are gaining a lot of attention as a result of their excellent chemical and structural integrity with easy deformability and possibilities for being incorporated into various functionalities. The characteristic chemical and physical properties of microgels result in their widespread application. Among their many applications in the current review, we will give an overview on the design principles and synthetic approaches of microgels for sensing applications and their uses for the removal of different environmental pollutants. It is important to understanding the mechanism of sensing and adsorption, which is important for exploring further advancement. In this review, we brief these aspects

Synthesis of Azetidinium-Functionalized Polymers Using a Piperazine Based Coupler

A bifunctional coupler bearing an azetidinium and an aminochlorohydrin group was synthesized in water as solvent starting with piperazine and epichlorohydrin. Conversion of the bifunctional coupler in aqueous solution with primary and secondary amines (hexylamine and diethylamine) were studied as a model reaction. Using the established reaction conditions, azetidinium-functionalized polytetrahydrofurans were prepared in a controlled way by reacting the coupler in water as solvent with amine-functionalized polytetrahydrofurans

[bmim][Br] as a Solvent and Activator for the Ga-Mediated Barbier Allylation: Direct Formation of an <i>N</i>‑Heterocyclic Carbene from Ga Metal

The room-temperature ionic liquid (RTIL) [bmim]­[Br] has been found to be an excellent green and inexpensive medium for the Ga-mediated allylation of aromatic and aliphatic aldehydes and ketones. The RTIL activated the metal via formation of a Ga–<i>N</i>–heterocyclic carbene complex that assisted in the completion of the reaction at ambient temperature with only 0.5 equiv of Ga and 1.2 equiv of allyl bromide with respect to the carbonyl substrates. The present protocol required a much shorter time than those reported in the literature using other metals and solvents and proceeded with good yields and excellent selectivity

Generation of Reactive Low-Valent Titanium Species Using Μetal−Αrenes as Efficient Organic Reductants for TiCl₃: Applications to Organic Synthesis

A comprehensive study on the use of metal−arene systems as organic reductants for TiCl3 has resulted in an efficient method for the generation of highly reactive low-valent titanium (LVT) reagents. The activated titanium species could be prepared by refluxing a mixture of substoichiometric amounts of arenes, TiCl3, and Li/Mg in THF or DME. Among the LVT reagents screened, TiCl3−Li−naphthalene−THF (reagent I) was the best for coupling of carbonyls to olefins. The reagent could carry out the McMurry olefination of both aromatic and aliphatic substrates at a lower temperature and in a much reduced time as compared to the conventional procedures. Subtle changes in the method of preparation of the LVT reagents influenced the stereoisomeric ratio of the olefins. The reagent was also useful for the synthesis of O- and N- heterocycles and vicinal diamines via intramolecular carbonyl coupling and reductive duplication of imines, respectively

NMR Spectrometric Studies of Complexation of [60]Fullerene with Series of Anisoles

Detailed 1H and 13C NMR spectrometric studies have been carried out to gain insight into the nature of molecular interactions of the electron donor−acceptor (EDA) complexes of [60]fullerene with a series of anisoles, namely, anisole, m-bromoanisole, and p-bromoanisole. [60]Fullerene has been shown to form 1:1 adducts with the above series of anisoles. Formation constants (K) for all the complexes have been determined from the systematic variation of the NMR chemical shifts of specific protons of the anisoles in the presence of [60]fullerene. The K values of [60]fullerene/anisole, [60]fullerene/m-bromoanisole, and [60]fullerene/ p-bromoanisole complexes yield good estimates of the Hammett ρ constant for the complexation reaction. To the best of our knowledge, this paper reports for the first time a very fruitful technique by which the concentrations of EDA complexes can be estimated from systematic variations of the 13C NMR signal

The time course of stomach ulceration and its prevention by different doses of PK

Stomach ulceration in mice was induced by oral administration of indomethacin (18 mg/kg body weight). Different doses of PK were used for the experiments. The ulcer indices were measured on different days 4 h after the last dose of PK and the values are mean ± S.E.M. (n = 15). < 0.01, < 0.001 compared to 1day ulcerated untreated mice; < 0.01, < 0.001 compared to the group III mice.<p><b>Copyright information:</b></p><p>Taken from "Healing Potential of (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration."</p><p>http://www.biomedcentral.com/1472-6882/8/3</p><p>BMC Complementary and Alternative Medicine 2008;8():3-3.</p><p>Published online 31 Jan 2008</p><p>PMCID:PMC2266895.</p><p></p

Photophysical and Theoretical Investigations on Fullerene/Phthalocyanine Supramolecular Complexes

The present paper reports the photophysical aspects of a very interesting and unique host−guest interaction between fullerene and phthalocyanines, viz., free base phthalocyanine (H2-Pc) and zinc-phthalocyanine (Zn-Pc), in toluene medium. Ground state electronic interaction between these two supramolecules has been evidenced from the observation of well-defined charge transfer (CT) absorption bands in the visible region. Vertical ionization potentials of the phthalocyanines have been determined utilizing CT transition energy. Magnitude of degrees of CT reveals that, in the ground state, 2−4% CT takes place. Binding constants (K) for the fullerene/phthalocyanine complexes were determined from the fluorescence quenching experiment. Large K values in the ranges ∼4.7 × 104 to 7.3 × 104 and 2.3 × 104 to 2.5 × 104 dm3·mol−1 were obtained for the 1:1 fullerene complexes of Zn and H2-Pc, respectively. Values of K suggest that both H2- and Zn-Pc could not serve as an efficient discriminators between C60 and C70. Theoretical calculations as well as 13C NMR studies establish that the orientation of C70 toward phthalocyanine is favored in end-on orientation, which proves that interaction between fullerenes and phthalocyanines were governed by the electrostatic mechanism rather than dispersive forces associated with π−π interaction

Steric Strain Release-Directed Regioselective Functionalization of <i>meso</i>-Methyl Bodipy Dyes

Starting from some meso-methyl Bodipy dyes, the corresponding meso-styryl derivatives were synthesized by regioselective Knoevenagel-type condensation with different aromatic aldehydes. The reactions were driven by the alleviation of the structural strain of the alkyl substituted Bodipys that could override the differential acidities of the methyl protons at the pyrrole ring of the Bodipy moiety

Comparative time dependent activity of PK and Omez in regulating the expression of tissue COX-1 isoform in acute gastric ulcerated mice

The COX-1 expression was quantified using Biovis MV500 software. Data are expressed as means ± SEM for fifteen mice. < 0.05, < 0.01 compared to normal mice, < 0.05 compared to the respective ulcerated mice, < 0.05 compared to the Omez-treated mice. N – normal mice, UU – ulcerated untreated mice, PK – ulcerated PK-treated mice, Omez – ulcerated Omez-treated mice.<p><b>Copyright information:</b></p><p>Taken from "Healing Potential of (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration."</p><p>http://www.biomedcentral.com/1472-6882/8/3</p><p>BMC Complementary and Alternative Medicine 2008;8():3-3.</p><p>Published online 31 Jan 2008</p><p>PMCID:PMC2266895.</p><p></p