Lifetime risk of CKD, by baseline BMI category and highest CKD stage attained.

The difference in lifetime risk or any CKD between persons with obesity and normal weight was statistically significant at the 1% level. No other differences were statistically significant. Abbreviations: CKD = Chronic Kidney Disease, BMI = Body Mass Index.</p

Lifetime risk of any CKD, by baseline BMI category and age.

The difference in lifetime risk of any CKD between persons age 50–64 with obesity and normal weight was statistically significant at the 1% level. No other differences were statistically significant. Abbreviations: CKD = Chronic Kidney Disease, BMI = Body Mass Index.</p

Model parameters for relative risks related to obesity and annual change in BMI.

Model parameters for relative risks related to obesity and annual change in BMI.</p

One-way sensitivity analysis of +/- 25% changes in key parameters on the difference in lifetime risk of any stage CKD between persons with obesity and persons with normal weight.

In the main analysis, the difference in lifetime risk between persons with normal weight and obesity was 8.5%. Bars to the left of this value in the figure show the change in results if parameters are decreased by 25% and bars to the right of this value show the change in results if the parameters are increased by 25%. Abbreviations: eGFR = estimated glomerular filtration rate.</p

Baseline characteristics of the Chronic Renal Insufficiency Cohort study Analytic sample.

Baseline characteristics of the Chronic Renal Insufficiency Cohort study Analytic sample.</p

Model parameters for annual change in eGFR based on person characteristics and conditions and baseline eGFR.

Model parameters for annual change in eGFR based on person characteristics and conditions and baseline eGFR.</p